PhD Research Project

My Shortlist0

This project is no longer listed in the FindAPhD database
and may not be available.

Click here to view other PhD studentship opportunities at Robert Gordon University.

IHW6 - Effect of genotype on the efficacy of metformin therapy in patients with Type 2 diabetes

Institution:

Robert Gordon University

Dept/School/Faculty:

Institute for Health & Welfare Research

PhD Supervisor:

Dr RM Knott

Application Deadline:

No more applications being accepted

Funding Availability:

Competition Funded PhD Project (European/UK Students Only)

PhD Research Project

Click here to visit the Robert Gordon University website

Type 2 diabetes is a metabolic disease that is associated with significant long term complications including cardiovascular disease and microvascular complications including diabetic retinopathy, nephropathy and neuropathy. Metformin is widely prescribed to regulate circulating levels of glucose but has a varied response due to compliance, adverse side effects, diet, genetics and the existence of co-morbidities. The aim of this project is to identify single nucleotide polymorphisms that may influence metformin efficacy and to evaluate them in a patient population. We will determine if poor response/compliance/outcome to metformin therapy is associated with genetic polymorphism and evaluate how this may inform future clinical practice. The candidate should have a background in biomedical sciences with particular interest in molecular biology, genetics and cell biology.

Candidates should be highly motivated with a strong commitment to academic research. A First Class, or a 2.1 Honours Degree (or equivalent) or a Masters Qualification in a relevant discipline is required. Relevant professional experience will also be considered. Each studentship provides full university fees for UK/EU applicants and a tax-free maintenance allowance of £13,590 per annum for 3 years (UK Research Council Rates). The studentship is available to start in October 2012. Interviews will be held on the 7th / 8th June 2012. Further details can be obtained at http://www.rgu.ac.uk/research/graduate-schools/applying-for-a-research-degree/funded-studentship-opportunities.

Funding Notes:

Studentship is open to UK/EU students only.
Applicants should apply on-line, uploading all required documents and quoting the IHW project reference as appropriate to the project you are applying for. Once an Apply Online account has been set up, please check the Yes box to “Are you applying for an advertised studentship?” and then select IHW project code from the drop down list.