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Prof Scott Cockroft
Applications accepted all year round
Funded PhD Project (European/UK Students Only)
About the Project
Funding is available for only one student to start in 2013
Non-covalent interactions are fundamental aspects of almost all chemical and biological processes. Solvent effects coupled with the precise positioning of interacting functional groups may be essential for the astonishing ligand binding affinities observed in biology. However, previous experimental studies concerning the influence of dispersion interactions, solvent shape and geometric positioning of interacting functional groups have been particularly limited. The aim here is to design and synthesise a new class of folding molecules for quantifying the effects of these variables on non-covalent interactions.
The student will receive training in a range of modern experimental and analytical techniques associated with physical organic chemistry including:
• organic synthesis, NMR spectroscopy, X-ray crystallography
• theoretical background in molecular recognition
• quantitative structure activity relationships, computational modelling.
For further information on the scope of research, please visit:
http://homepages.ed.ac.uk/scockrof/research.php
Non-covalent interactions are fundamental aspects of almost all chemical and biological processes. Solvent effects coupled with the precise positioning of interacting functional groups may be essential for the astonishing ligand binding affinities observed in biology. However, previous experimental studies concerning the influence of dispersion interactions, solvent shape and geometric positioning of interacting functional groups have been particularly limited. The aim here is to design and synthesise a new class of folding molecules for quantifying the effects of these variables on non-covalent interactions.
The student will receive training in a range of modern experimental and analytical techniques associated with physical organic chemistry including:
• organic synthesis, NMR spectroscopy, X-ray crystallography
• theoretical background in molecular recognition
• quantitative structure activity relationships, computational modelling.
For further information on the scope of research, please visit:
http://homepages.ed.ac.uk/scockrof/research.php
Funding Notes
Previous research experience in synthetic chemistry is required for Physical Organic Chemistry. Applicants must be in possession of (or expecting to obtain) a first class or upper-second class degree (or equivalent) in Chemistry, Biochemistry or other cognate discipline before the start of the PhD. Applicants MUST be either be EU, or UK nationals who have been resident in the UK for the past three years with a 2.i grade or higher, OR be an exceptional EU national ranked within the top 5% of their class.
Please email your CV, including a brief description of previous research experience.
Please email your CV, including a brief description of previous research experience.
How good is research at University of Edinburgh in Chemistry?
Research output data provided by the Research Excellence Framework (REF)
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Career overview
Professor Scott L. Cockroft holds a Personal Chair of Supramolecular Chemistry at the University of Edinburgh. The research conducted in the Cockroft group encompasses organic chemistry and bionanotechnology, focusing on the combination of synthetic and biological molecules to investigate the physical organic chemistry that underlies molecular interactions and the functioning of molecular machines. Professor Cockroft's work includes significant contributions to the understanding of molecular recognition, non-covalent interactions, and the development of molecular machines.
Research interests
Professor Cockroft's research focuses on physical organic chemistry, molecular recognition, non-covalent interactions, supramolecular chemistry, and molecular machines. The research in the Cockroft group spans organic chemistry and bionanotechnology, combining molecules of synthetic and biological origins to examine the physical organic chemistry underpinning molecular interactions and the operation of molecular machines.
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