Faculty of Biology, Medicine and Health

The University of Manchester

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  Using the pain feedback related negativity to investigate placebo analgesia

Prof W El-Deredy, Dr D Talmi  No more applications being accepted  Competition Funded PhD Project (European/UK Students Only)

About the Project

The neuroscience of associative learning has shown that when an incoming stimulus deviates from the stimulus that was expected, the brain generates an error signal (prediction error), which is proportional to the magnitude of the deviation. The prediction error signal eventually leads to learning or extinction and supports optimal decision making.

Chronic pain patients routinely make predictions about the pain that they may experience. Such predictions drive their behavioural choices, sometimes in maladaptive ways, and are known to have a role in the development of mental health problems and physical disability. The aim of the project is to explore the relationship between pain predictions and the experience of pain.

This project will investigate the electrophysiological signature of prediction errors (an event-related component known as the feedback related negativity) in the context of pain and experimental placebo analgesia in order to understand the mechanisms of the placebo response.

This 4-year full-time studentship provides full support for tuition fees, minimum annual tax-free stipend of 13, 590 and a conference/travel allowance. The project is due to commence October 2013 and is open to UK/EU nationals only due to the nature of the funding.

The successful candidate will benefit from extensive training in psychology, pharmacological manipulations; randomised clinical trials and public engagement in science.

This PhD will provide an ideal platform to progress onto an academic career in medicine, clinical psychology, clinical trials or research support.

Applicants should hold a minimum upper-second honours degree (or equivalent) in psychology, biology, medicine or neuroscience.
A Masters qualification in a related subject would be an advantage. As would experience in the methods of experimental psychology, having designed your own study; knowledge of neurobiology as well as programming experience.

Please direct applications in the following format to Professor Wael El-Deredy ([Email Address Removed])

• Academic CV
• Official academic transcripts
• Contact details for two suitable referees
• A personal statement (750 words maximum) outlining your suitability for the study, what you hope to achieve from the PhD and your research experience to date.

Any enquiries relating to the project and/or suitability should be directed to Professor Wael El-Deredy. Applications are invited up to and including Monday 7 January 2013.

The Faculty of Medical and Human Sciences is offering the opportunity of over 50 fully-funded PhD projects to outstanding candidates seeking research training from October 2013. Details can be found on our website:

http://www.mhs.manchester.ac.uk/postgraduate/studentships/

http://www.mhs.manchester.ac.uk/postgraduate/

http://www.manchester.ac.uk/research/Wael.el-deredy/personaldetails

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Where will I study?

 About the Project

Faculty of Biology, Medicine and Health

Tackle real world challenges, make a difference, and elevate your career with postgraduate research in the Faculty of Biology, Medicine and Health at Manchester. From biochemistry to neuroscience, cancer sciences to medicine, audiology to mental health and everything in between, we offer a wide range of postgraduate research projects, programmes and funding which will allow you to immerse yourself in an area of research you’re passionate about.

Why study at the Faculty of Biology, Medicine and Health?

Experience PhD life as part of a diverse postgraduate research community of more than 1,000 postgraduate researchers at the 29th most international university in the world (Times Higher Education, 2023).

Ranked the best place to live in the UK (The Economist Global Liveability Index, 2022), Manchester boasts world-class culture, iconic sports, a thriving music and food scene, and much more. It's not just a place to research, it's a place to call home.

With 93% of research activity at the University rated as 'world-leading' or 'internationally excellent' (Research Excellence Framework, 2021), you'll get the chance to have an impact on global health and science challenges.

1000+

postgraduate students

1

PhD

6th

in the UK - QS (2025)

Manchester  United Kingdom

main campus

About the Faculty of Biology, Medicine and Health

At Manchester, postgraduate researchers are at the heart of our mission to tackle pressing global challenges in biological, medical and healthcare sciences - and you could be too.

By choosing Manchester for your postgraduate research, you’ll be joining a university with an exceptional research reputation, where 93% of research is world-leading or internationally excellent (REF, 2021) and where your work will have real-world impact.

You’ll research in world-class facilities alongside leading experts at the forefront of innovation, collaborating across disciplines to pioneer new treatments, advance scientific knowledge, and improve healthcare globally.

Supported by our dedicated Doctoral Academy and strong industry links, you'll experience PhD life in a vibrant, welcoming and diverse postgraduate research community.

And you’ll leave with the specialist knowledge, research experience and transferable skills that will shape your future in academia, research or industry.





Main campus

The University of Manchester

Manchester

North West

United Kingdom