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Prof M Leake, Dr Peter O'Toole
No more applications being accepted
Funded PhD Project (Students Worldwide)
About the Project
A 3 year funded PhD studentship in biological physics/biophysics is available is available in the research group of Prof. Mark Leake, jointly hosted by the Departments of Physics (http://www.york.ac.uk/physics/) and Biology ((http://www.york.ac.uk/biology/) at the University of York starting in October 2013
The project will focus on the development of novel optical super-resolution microscopy methods for single-molecule biophysics experimentation. These include but are not limited to: nanoscale real-time 3D single particle tracking methods in living biological cells, super-resolution fluorescence imaging involving photoactivation/switching and dye blinking, multli-colour and multi-polarization single-molecule fluorescence imaging in living cells and the integration of other single-molecule biophysics molecules to be combined with super-resolution optical microscopy. The project will involve elements of bespoke optical microscopy construction as well as computational control and analysis development.
The PhD student will apply these new methods to real experimental investigations involving living cells in order to investigate unresolved questions from the life sciences, including but not limited to questions concerning the way the DNA is replicated, how cells divide and how cells are energized. The PhD student will benefit significantly from the joint appointment of Prof. Leake’s post between the Department of Physics and Biology, allowing the PhD student to develop new skills in methods of the biological sciences.
The successful candidate will work closely with Prof. Leake’s experimental and analytical collaborators based both in the UK and beyond. Further details on the area of this research can be found at http://single-molecule-biophysics.org/. Potential candidates must have a good degree in Physics or a related discipline and a strong interest in bridging into areas of the life sciences. Experience with Matlab or LabView computer programming, or equivalent, is also highly desirable.
The 3-year PhD studentship will be registered in Physics, hence please apply directly to the physics department. The studentship comes with an EPSRC minimum stipend of £13,726 p.a. [*N.B., this is the 2013/14 minimum EPSRC stipend rate. Subject to annual adjustment.]. EU and overseas students are also encouraged to apply.
We encourage informal enquiries about the project, which can be made to Prof. Mark Leake ([Email Address Removed])
Full applications can be made online at http://www.york.ac.uk/study/postgraduate/apply/.
Applications will continue to be considered until a suitable candidate is found.
The project will focus on the development of novel optical super-resolution microscopy methods for single-molecule biophysics experimentation. These include but are not limited to: nanoscale real-time 3D single particle tracking methods in living biological cells, super-resolution fluorescence imaging involving photoactivation/switching and dye blinking, multli-colour and multi-polarization single-molecule fluorescence imaging in living cells and the integration of other single-molecule biophysics molecules to be combined with super-resolution optical microscopy. The project will involve elements of bespoke optical microscopy construction as well as computational control and analysis development.
The PhD student will apply these new methods to real experimental investigations involving living cells in order to investigate unresolved questions from the life sciences, including but not limited to questions concerning the way the DNA is replicated, how cells divide and how cells are energized. The PhD student will benefit significantly from the joint appointment of Prof. Leake’s post between the Department of Physics and Biology, allowing the PhD student to develop new skills in methods of the biological sciences.
The successful candidate will work closely with Prof. Leake’s experimental and analytical collaborators based both in the UK and beyond. Further details on the area of this research can be found at http://single-molecule-biophysics.org/. Potential candidates must have a good degree in Physics or a related discipline and a strong interest in bridging into areas of the life sciences. Experience with Matlab or LabView computer programming, or equivalent, is also highly desirable.
The 3-year PhD studentship will be registered in Physics, hence please apply directly to the physics department. The studentship comes with an EPSRC minimum stipend of £13,726 p.a. [*N.B., this is the 2013/14 minimum EPSRC stipend rate. Subject to annual adjustment.]. EU and overseas students are also encouraged to apply.
We encourage informal enquiries about the project, which can be made to Prof. Mark Leake ([Email Address Removed])
Full applications can be made online at http://www.york.ac.uk/study/postgraduate/apply/.
Applications will continue to be considered until a suitable candidate is found.
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