Modelling the bladder and lower urinary tract

The main function of the bladder is storage and controlled release of urine, and problems with this system can result in a wide range of distressing symptoms. Despite its importance, there are several aspects of bladder and lower urinary tract function that are not well understood, and this can make it difficult for clinicians to make a correct diagnosis. The aim of this project will be to develop models of the bladder and lower urinary tract that are based on the physiological and anatomical information that is available in the literature, and to use these models to examine gaps in our understanding of how this system works. One specific focus will be the way that the bladder wall changes as it fills, and the way that the bladder senses fullness.