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  Remotely triggered scaffolds for controlled degradation and release of pharmaceuticals


   Institute for Science and Technology in Medicine

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  Dr C Hoskins  Applications accepted all year round  Self-Funded PhD Students Only

About the Project

Advancement in knowledge of cell-materials interaction has led to development of novel materials for use in implant technology, in vitro expansion of cells for regenerative medicine and medical diagnostics. Scaffold materials provide the architecture to support 3D tissue growth, although often such materials cause problems for long-term regeneration. Biodegradable scaffolds that collapse after a fixed time period, either naturally or after external stimulus, are therefore advantageous. Addition of nanoparticles into the intrinsic structure of a scaffold can enhance functionality and lead to exciting new properties including ability to remotely trigger structural collapse and drug release. Here we are interested in the incorporation of such nanoparticles into a thermo-responsie biocompatible scaffold. This sophisticated system will result in remotely triggered scaffolds for controlled degradation and release of pharmaceuticals.

Candidate Profile:
Essential: First or upper class degree (or equivalent) chemistry, pharmacy or in any relevant scientific discipline.
Good laboratory based skills.
Ability to communicate well.
English Language certificate (where applicable)

Desirable: Master's degree in relevant subject area
Additional research experience
Experience in scientific writing.

Funding Notes

International, UK and EU self funded students are welcome to apply.