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  Microstructure behaviour in the mouth: Design Principles for Engineering Intelligent Foods


   School of Chemical Engineering

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Dr S Bakalis Prof I Norton  Applications accepted all year round  Competition Funded PhD Project (Students Worldwide)

About the Project

A range of food-related diseases require production of ‘healthy’ food products that are of reduced fat and caloric content but retain their high quality characteristics. Despite advances in the area of physical sciences in creating microstructures with advanced property functions there is still a need to understand the performance of such products during oral processing. An engineering understanding of the phenomena occurring during eating will result in a new approach of Food Product Design and the possibility to engineer healthy products of enhanced sensory characteristics.
The objective of this study will be to obtain an engineering understanding of phenomena occurring during eating of liquid multiphase products. Phenomena such as flow patterns, micromixing and microstructure behaviour during mastication will be examined. This will be followed by relating in-vivo microstructure behaviour to in-vitro measurements obtained using a range of
experimental tools such as rheology and soft tribology.

Indicative objectives:
1) Develop and implement techniques that would allow quantification of flow and micro-mixing phenomena occurring in the mouth using a compilation of optical techniques, tracers, pressure probes and tomographic techniques.
2) Understand the effect of formulation during in-mouth behaviour
3) Extend and validate existing in-vitro mouth models to study microstructure parameters
4) Understand the relative importance of physical parameters that determine microstructure behaviour in the mouth.

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Project supervisors

Career overview

Professor Serafim Bakalis is an Honorary Professor in Structured Products at the University of Birmingham, where he has been a University Academic Fellow since 2005. He holds a PhD in Food Engineering from Rutgers University, obtained in 1999, and also earned an MSc in Food Engineering from the same institution in 1996. Prior to that, he completed a BSc in Chemical Engineering at the National Technical University of Athens in 1994. Professor Bakalis''s research focuses on engineering-related aspects, particularly the effects of processing on microstructure control and the extension of traditional unit operations to enhance the performance of various consumer product formulations. He is currently the Principal Investigator of an EPSRC/DTI-funded project aimed at developing low-salt products that maintain their sensory attributes. Throughout his career, he has developed a wide range of skills and techniques while interacting with leading industries, all while contributing to teaching and administration within the School of Chemical Engineering. Professor Bakalis is also actively involved in professional organisations, including the Institution of Chemical Engineers, the Institute of Food Technologists, and the Greek Chamber of Engineers, and serves on the Scientific Committee of the Food Faraday Knowledge Transfer Network.


Research interests

Professor Serafim Bakalis''s research spans a range of engineering-related aspects with a focus on understanding the effect of processing on microstructure control. He extends traditional unit operations to include the performance of formulations of various consumer products. Currently, he is the Principal Investigator of an EPSRC/DTI-funded project aimed at delivering low-salt products without compromising their sensory attributes. His doctoral supervision includes topics such as the use of positron emission particle tracking (PEPT) to investigate mixing processes, characterisation of thermal processes using time temperature integrators, development of X-Ray microCT for understanding the effect of formulation and processing in porous structures, modelling the performance of complex microstructures in the mouth, and electroencephalography-based investigation of sensory responses to food consumption.

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Career overview

Professor Ian Norton holds a BA in Chemistry from the University of York, obtained in 1977, and a DPhil in Fast Reaction Kinetics of Conformational Transitions in Polysaccharides from the same institution in 1980. He previously served as Chief Scientist at Unilever before taking on the role of Professor of Soft Solid Microstructural Engineering in the Department of Chemical Engineering at the University of Birmingham. His doctoral research focused on the physical chemistry of polysaccharide conformational transitions, specifically examining fast reaction kinetics and thermodynamics. In industry, Professor Norton transitioned to the field of colloids and interfaces, developing a microstructure approach that designs material properties through ingredient selection and their physical interactions. This approach has been instrumental in the design of various food and personal care products, leading to over 60 granted patents and numerous innovative products still available today. At the University of Birmingham, he leads the Food Formulation Engineering Research Group, where he continues to apply this methodology to a broader range of soft solids, including those used in food, personal care, cosmetics, paints, pharmaceuticals, and cleaning products.


Research interests

Professor Norton''s research focuses on food formulation engineering, particularly in the development of new methods and techniques for food processing. His interests include emulsions and emulsification, interfacial design concerning chemical composition and material properties, and the physical chemical aspects of nutrition and health. He investigates how food microstructure can influence food consumption and the dynamics of macronutrient release. Additionally, he studies encapsulation and targeted delivery, colloids at surfaces and bio-surfaces, crystallisation and control of crystal morphology, and the material properties of soft solids, including rheology and flow behaviour. Professor Norton has authored over 100 refereed papers and holds more than 60 patents related to biopolymers, fat physical chemistry, emulsions, and material science, contributing significantly to innovations in food and personal care products.

View Professor Ian Norton's profile