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Dept/School Department of Biology, University of York
Project Supervisor(s) Dr P Pryor
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Pathogen manipulation of intracellular membrane trafficking

Lysosomes are cellular organelles that degrade phagocytosed material and hence they form part of our innate immunity. However, some microbes and parasites such as Salmonella and Leishmania , can survive intracellularly by avoiding the destruction by the lysosome. This project aims to develop an in vitro lysosome-phagosome fusion assay and investigate how pathogens can alter intracellular membrane traffic to create their replicative niche.
Research Assessment Exercise (RAE) 2008 Results

Unit of Assessment: Biological SciencesWhat is the RAE?
FTE Category A Staff Submitted4*3*2*1*U/C
57.5125%35%30%10%0%
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