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Dept/School School of Biosciences, University of Birmingham
Project Supervisor(s) Prof M Pallen
Funding Availability
Competition Funded Project (European Students Only) - See Funding Key for more detailsCompetition Funded Project (European/UK Students Only)
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Bacterial Pathogenomics and Protein Secretion

I am a medically qualified scientist (MD/PhD) working at the interface between bacterial genomics, bioinformatics and pathogenesis and with a research group benefitting from research council funding. Current interests focus on genome sequencing as a tool for studying the epidemiology and evolution of bacterial pathogens and on the structure, function and evolution of bacterial protein secretion systems. Applications are welcome in both areas. Applicants keen to pursue a genomics project should provide evidence of an aptitude in bioinformatics.

Funding Notes
UK and EU applicants will be considered for funding upon receipt of a completed application form and 2 references.

Applicants from other countries will be considered, providing they have their own source of funding.


Lewis T, Loman NJ, Bingle L, Jumaa P, Weinstock GM, Mortiboy D, Pallen MJ (2010) Use of high-throughput whole-genome sequencing to dissect the epidemiology of Acinetobacter baumannii isolates from a hospital outbreak. J Hospital Infection 76 (In press).

Loman NJ, Snyder LA, Linton JD, Langdon R, Lawson AJ, Weinstock GM, Wren BW, Pallen MJ. (2009) Genome sequence of the emerging pathogen Helicobacter canadensis. J Bacteriol. 191: 5566-7.

Snyder LA, Loman NJ, Fütterer K, Pallen MJ. (2009) Bacterial flagellar diversity and evolution: seek simplicity and distrust it? Trends Microbiol. 17:1-5.

Chaudhuri RR, Loman NJ, Snyder LA, Bailey CM, Stekel DJ, Pallen MJ (2008). xBASE2: a comprehensive resource for comparative bacterial genomics. Nucleic Acids Res 36(Database issue):D543-6.

Pallen MJ, Wren BW. (2007) Bacterial pathogenomics. Nature. 449:835-42
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Tobe T, Beatson SA, Taniguchi H, Abe H, Bailey CM, Fivian A, Younis R, Matthews S, Marches O, Frankel G, Hayashi T, Pallen MJ. (2006) An extensive repertoire of type III secretion effectors in Escherichia coli O157 and the role of lambdoid phages in their dissemination. Proc Natl Acad Sci U S A. 103(40):14941-6.
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