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| Dynamics of biomolecular association processes | ||||||||||||||||||
How life emerges from complex molecular interactions is a key question for modern biology. Complex biosystems arise from the orchestrated production of many biomolecules, which then associate to form intricate networks that involve both transient interactions and/or stable assemblies. We seek to study the details of biomolecular interaction processes ranging from long-range diffusional encounters, to the details of how native complexes form after the initial encounter. In collaboration with mathematicians and experimental bioscientists we will use computer simulation techniques (such as Brownian Dynamics, Molecular Dynamics) to study the detailed structural and energetic aspects of biomolecular association. Of particular interest is the study of the spontaneous self-assembly of viral capsids from their protein building blocks in collaboration with Prof. Reidun Twarock. Funding Notes This research project is one of a number of projects in the department. It is in competition for funding with the other projects. Usually the project which receives the best applicant will be awarded the funding. The funding is available to citizens of a number of European countries (including the UK). In most cases this will include all EU nationals. However full funding may not be available to all applicants. |
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Research Assessment Exercise (RAE) 2008 Results
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