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| Defining the role of the ABI4 transcription factor in the sugar regulated control of storage oil breakdown in Arabidopsis | ||||||||||||||||||
Post-germinative fatty acid catabolism is inhibited by both sugars and ABA in a tissue specific fashion, and we have recently discovered that the APETALA2 transcription factor ABI4 mediates this regulation in Arabidopsis (Penfield et al. 2006, Plant Cell 18: 1887-1899). This is one of only a handful of cases where a specific regulatory protein has been linked to the regulation of primary carbon metabolism in plants. ABI4 and ABA control multiple sugar regulated metabolic processes in plants, suggesting that the function of ABI4 is of central importance in the feedback regulation of plant metabolism by sugar status. This project aims to establish how ABI4 regulates oil breakdown. A combination of molecular and biochemical genetic approaches will be used to identify gene targets of the ABI4 transcription factor. The role of these gene targets will be further evaluated by overexpression and mutant analysis. Funding Notes This research project is one of a number of projects in the department. It is in competition for funding with the other projects. Usually the project which receives the best applicant will be awarded the funding. The funding is available to citizens of a number of European countries (including the UK). In most cases this will include all EU nationals. However full funding may not be available to all applicants. |
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Research Assessment Exercise (RAE) 2008 Results
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