We have 478 bioinformatics PhD Projects, Programmes & Scholarships

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bioinformatics PhD Projects, Programmes & Scholarships

We have 478 bioinformatics PhD Projects, Programmes & Scholarships

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Next Generation AI-driven Tools for Genetic Variant Extraction, Visualisation and Classification

Accurate genomic variant reporting is essential for rare disease diagnosis, yet scientific papers, clinical reports, and database submissions routinely contain erroneous variant descriptions and omit crucial clinical evidence such as ACMG scores and pathogenicity classifications. Read more
 Supervisors: Dr S Pettifer, Dr PF Freeman, Dr R Batista-Navarro
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Molecular stratification of subglottic stenosis to identify therapeutic pathways

Subglottic stenosis (SGS) is a progressive fibrotic disease that causes narrowing of the subglottic trachea. Causes are autoimmune (granulomatosis with polyangiitis (GPA) or ANCA-negative vasculitis), iatrogenic (after intubation or trauma) or idiopathic, with an incidence of 1 in 400 000 patients per year[1]. Read more
 Supervisors: Prof C Buckley, Prof K Midwood, Prof SW Winter, Dr C Morrell
 1 December 2026  PhD Research Project  Funded PhD Project (Students Worldwide)
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Inducing Tertiary Lymphoid Structures in Metastatic Colorectal Cancer to Enable Effective Immunotherapy for Advanced Disease

The generation and propagation of adaptive immune responses are normally confined to secondary lymphoid organs (SLOs), specialised tissues in which complex stromal cell networks coordinate interactions required for effective lymphocyte activation and differentiation. Read more
 Supervisors: Prof M Coles, Prof D Withers, Prof C Buckley
 1 December 2026  PhD Research Project  Funded PhD Project (Students Worldwide)
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Investigating the spatial organisation of pathogenic cell niches in chronic inflammatory diseases

Are you interested in understanding how the spatial arrangement of cells shapes tissue inflammation? The immune system functions within highly organised tissue environments, where interactions between immune, stromal and structural cells are essential for maintaining health. Read more
 Supervisors: Dr S Sansom, Prof C Monaco, Dr M Friedrich, Dr A Hallou
 1 December 2026  PhD Research Project  Funded PhD Project (Students Worldwide)
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Disease Mechanisms: From Phenotypic Discovery to New Therapeutic Targets

Projects in this direction will investigate molecular mechanisms that drive major human diseases and identify new therapeutic targets. Read more
 Supervisor: Prof X Lei
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Synthetic Biology and Biocatalysis for Natural-Product Discovery and Production

Projects in this direction aim to uncover how nature produces structurally complex bioactive natural products and use these insights to develop new biosynthetic and biocatalytic systems. Read more
 Supervisor: Prof X Lei
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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A structural biology approach to understand IMPDH2 rod-ring structures in Embryonic Stem Cells

IMPDH2 is a critical enzyme responsible for the rate limiting step of purine nucleotide biosynthesis. In naïve pluripotent stem cells, it forms large rod-ring structures (RRs) which are hypothesised to control the enzyme’s output when the pool of guanine nucleotides is in high demand. Read more
 Supervisors: Dr D Turner, Prof D J Rigden
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Leveraging and developing Deep Learning-based methods for experimental structural biology

Deep Learning methods have had a huge recent impact on biology in recent years. for example, AlphaFold 2 and 3 (AF2/3) can predict the structure of most proteins with unprecedent accuracy. Read more
 Supervisors: Prof D J Rigden, Dr R Keegan, Dr IB Barsukov
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Regulation of genome stability and human disease

Poly(ADP-ribose) polymerases (PARPs) are the major family of enzymes that synthesize an abundant posttranslational protein modification called ADP-ribosylation. Read more
 Supervisor: Prof I Ahel
 1 December 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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PhD studentships with the South West Biosciences Doctoral Training Partnership (SWBio DTP)

The BBSRC-funded SWBio DTP involves a partnership of world-renown universities, research institutes and industry, based mainly across the South West and Wales. Read more
 Funded PhD Programme (UK Students Only)  4 Year PhD Programme  BBSRC Doctoral Training Partnership
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PhD studentships with the South West Biosciences Doctoral Training Partnership (SWBio DTP)

The BBSRC-funded SWBio DTP involves a partnership of world-renown universities, research institutes and industry, based mainly across the South West and Wales. Read more
 Funded PhD Programme (UK Students Only)  4 Year PhD Programme  BBSRC Doctoral Training Partnership
More details

PhD studentships with the South West Biosciences Doctoral Training Partnership (SWBio DTP)

The BBSRC-funded SWBio DTP involves a partnership of world-renown universities, research institutes and industry, based mainly across the South West and Wales. Read more
 Funded PhD Programme (UK Students Only)  4 Year PhD Programme  BBSRC Doctoral Training Partnership
More details

PhD studentships with the South West Biosciences Doctoral Training Partnership (SWBio DTP)

The BBSRC-funded SWBio DTP involves a partnership of world-renown universities, research institutes and industry, based mainly across the South West and Wales. Read more
 Funded PhD Programme (UK Students Only)  4 Year PhD Programme  BBSRC Doctoral Training Partnership
More details

PhD studentships with the South West Biosciences Doctoral Training Partnership (SWBio DTP)

The BBSRC-funded SWBio DTP involves a partnership of world-renown universities, research institutes and industry, based mainly across the South West and Wales. Read more
 Funded PhD Programme (UK Students Only)  4 Year PhD Programme  BBSRC Doctoral Training Partnership
More details

PhD studentships with the South West Biosciences Doctoral Training Partnership (SWBio DTP)

The BBSRC-funded SWBio DTP involves a partnership of world-renown universities, research institutes and industry, based mainly across the South West and Wales. Read more
 Funded PhD Programme (UK Students Only)  4 Year PhD Programme  BBSRC Doctoral Training Partnership