We have 1,183 biology PhD Projects, Programmes & Scholarships

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biology PhD Projects, Programmes & Scholarships

We have 1,183 biology PhD Projects, Programmes & Scholarships

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How proteins fold on the ribosome in real time

De novo protein folding is the fundamental process by which a polypeptide chain acquires its native conformation for the first time. Read more
 Supervisor: Dr IB Bukvin
 8 December 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Mechanism of transcription-coupled splicing

Accurate gene expression in eukaryotic cells requires tight coordination between transcription and pre-mRNA splicing. During transcription by RNA polymerase II (Pol II), the spliceosome removes introns from nascent RNAs co-transcriptionally. Read more
 Supervisor: Dr S Zhang
 8 December 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Machine learning for finding macromolecules in cells

The aim of this PhD project is to develop computer software for in situ structural biology projects. Specifically, software tools for the identification of macromolecular complexes in cryo-EM/cryo-ET data sets collected on thinned human and budding yeast cells. Read more
 Supervisor: Dr D Barford
 8 December 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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The macromolecular basis of nuclear remodelling in humans

Our lab focuses on understanding the processes which lead to a reshaping of the nuclear compartment in health and disease. The nucleus is continuously reshaped by the cytoskeletal filaments that surround it. Read more
 Supervisor: Dr M Allegretti
 8 December 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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The life cycle of ecDNA

A major focus of the lab is understanding the links between replication and mutagenesis (1‑4). Extrachromosomal DNA (ecDNA) circles are present in a substantial proportion of cancers and frequently harbour oncogenes that drive tumour proliferation (5). Read more
 Supervisor: Dr J Sale
 8 December 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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TRIM21 degradation of viruses and aggregates

TRIM21 is the cytosolic E3 ligase and antibody receptor responsible for intracellular antibody immunity. Unlike other ubiquitin ligases, TRIM21 doesn’t have a defined substrate but is directed towards its targets by antibodies. Read more
 Supervisor: Dr L James
 8 December 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Replicating RNA with RNA

A critical event in the origin of life is thought to have been the emergence of an RNA molecule capable of self-replication as well as mutation, and hence evolution towards ever more efficient replication. Read more
 Supervisor: Dr P Holliger
 8 December 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Where do cells go in the human embryo?

The first two weeks of human development transform a single-cell into a complex, bilaminar embryo. During this critical period, cells acquire distinct identies and organise into increasingly complex tissue architectures. Read more
 Supervisor: Dr M Shahbazi
 8 December 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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How the embryo gets its shape

The McDole lab seeks to understand how complex 3D structures in the embryo are sculpted from initially homogenous cell populations. Read more
 Supervisor: Dr K McDole
 8 December 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Visualizing cellular proteostasis

Each cell relies on thousands of internal biochemical reactions, carried out by around ten thousand different types of proteins. These cellular proteins, collectively known as the proteome, must be synthesized in precise quantities, undergo correct folding, and be accurately localized within the cell. Read more
 Supervisor: Dr J Fedry
 8 December 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Protein maturation, quality control, and disease

Cells are amazingly organized entities. Their resident proteins, nucleic acids, and small molecules are assembled into functional modules and segregated among numerous membrane-bound cellular compartments. Read more
 Supervisor: Dr R Hegde
 8 December 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Drugging daily clocks in a dish

Many commonly used drugs would benefit from considering daily biological timing but mechanistic understanding of circadian medicine is limited (Cederroth et al). Read more
 Supervisor: Dr J O'Neill
 8 December 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Defining neuro-immune circuits in viral infection

The nervous system provides a wide range of signals to immune cells residing in peripheral tissues such as the lung, the salivary glands, the gut or the female reproductive tract. Read more
 Supervisor: Dr N Rodriguez
 8 December 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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How does Wnt and Notch (Wntch) signalling coordinate cell fate assignment during gastrulation?

Gastrulation is a pivotal stage in development where an initially uniform mass of cells transforms into an organised structure with distinct cell types arranged along the three body axes. Read more
 Supervisors: Dr D Turner, Dr D Wilkinson
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Understanding post-translational modifications during viral infection

In this project, you will be working to understand how viruses such as coronaviruses, caliciviruses and picornaviruses interact with infected cells, with a focus on post-translational modifications. Read more
 Supervisor: Dr E Emmott
 Year round applications  PhD Research Project  Self-Funded PhD Students Only