We have 1,182 biology PhD Projects, Programmes & Scholarships

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biology PhD Projects, Programmes & Scholarships

We have 1,182 biology PhD Projects, Programmes & Scholarships

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Development of antibody-drug conjugates (ADCs) for oncology indications

A major challenge in cancer therapy is to develop therapeutic agents that selectively target tumour cells but are not harmful to normal tissue. Read more
 Supervisors: Prof K Pors, Dr Muhammad Wahajuddin, Prof R Falconer
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating genetic and circadian rhythm effects on radiotherapy side effects for breast cancer

Project. Radiotherapy is an effective form of cancer therapy that targets high energy irradiation to the tumour volume, resulting in destruction of cancer cells and improved survival. Read more
 Supervisors: Dr C J Talbot, Dr TR Rattay
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Mechanisms of epigenetic memory by Polycomb proteins

  Research Group: Francis Lab, Biochemistry of Epigenetic Inheritance
A funded position is available for a PhD student with a strong interest in biochemistry and biophysics for a project in the area of epigenetic regulation and transcription memory by Polycomb proteins. Read more
 Supervisor: Dr N Francis
 Year round applications  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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The role of DNA topology in epigenetic regulation by Polycomb proteins

  Research Group: Francis Lab, Biochemistry of Epigenetic Inheritance
Project Description. Correct use of the genome is at the heart of cell function and development. The primary sequence of DNA holds its essential information, yet the organization and structure of DNA also encode information. Read more
 Supervisor: Dr N Francis
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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MSc by Research: Molecular mechanisms underlying aphid effector virulence activity

Pests and diseases are a major threat to food security with losses ranging between 20-40%. Aphids are one of the most devastating insect pests, globally. Read more
 Supervisor: Dr J Bos
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Defying Mendel’s laws: developing tools to understand the principles of epigenetic inheritance in tomato plants

In plants, phenotypic innovation is not exclusively encoded in DNA sequences. Some heritable new traits are associated with modifications on the DNA, such as DNA methylation. Read more
 Supervisor: Dr C Martinho
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Heart failure and fatal epilepsy caused by unbranched glycogen

The accumulation and precipitation of unbranched glycogen in human tissues as toxic polyglucosan bodies (PB) is the cause of cardiomyopathy… Read more
 Supervisors: Prof Sir Philip Cohen, Dr K Swatek
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Reporting on destruction – developing plant-based assays for PROTAC degrader activity

Protein Targeting Chimera (PROTAC) degraders are small molecules able to recruit a ubiquitin ligase to a protein of interest and promote degradation. Read more
 Supervisors: Dr P Hemsley, Prof A Ciulli, Dr H Drost
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Role and mechanism of the bacterial Type VI secretion system

Many species of bacteria use a contractile nanomachine known as the Type VI secretion system (T6SS) to deliver a wide range of toxic proteins, known as ‘effectors’, directly into neighbouring cells. Read more
 Supervisor: Prof S Coulthurst
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Characterisation of human induced pluripotent stem cell derived kidney organoid system for use in drug discovery

Only 5% of all drugs tested in animal models are approved for human applications. Most of these failures are due to unexpected toxicity or lack of efficacy. The poor translation from small mammal studies to humans often causes this challenge. Read more
 Supervisor: Dr PD Davies
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Exploring Bacillus biocontrol of Phytophthora raspberry root rot disease

Domestic crop production, increasingly reliant on reduced fertiliser and agrochemical inputs whilst also achieving high yields, is necessary to maintain a high level of food security in the UK. Read more
 Supervisors: Dr A Holmes, Prof N Stanley-Wall
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Targeting ‘Undruggable’ Oncoproteins via Induced Proximity

Many well-established cancer drivers, such as K-Ras and β-catenin, have long been considered ‘undruggable’, as traditional drug development approaches have failed to effectively inhibit their activity. Read more
 Supervisors: Prof G Sapkota, Dr S Virdee
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Functional mechanisms and inhibition of biomedically important calcium channels

Ion channels are key components in every cell, bridging cell and organellar membranes for the traversal of charged species. Calcium channels are of particular physiological importance because of the central role calcium plays in cell signalling and cell death. Read more
 Supervisors: Prof U Zachariae, Prof R Sknepnek
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Optimizing plant cell wall glycan extraction to support plant health and biotechnology research

Plant cell wall glycans are a major component of plant biomass, essential for plant physiology, development, and protection against environmental stress and disease. Read more
 Supervisor: Dr D Ndeh
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Identification of the molecular pathways that guide tissue regeneration.

  Research Group: Development, Regeneration and Neurophysiology
The study of regenerative biology aims to elucidate the innate ability of organisms to replace tissues or organs after they have been removed or damaged. Read more
 Supervisor: Dr H Roehl
 Year round applications  PhD Research Project  Self-Funded PhD Students Only