We have 926 cell biology PhD Projects, Programmes & Scholarships

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cell biology PhD Projects, Programmes & Scholarships

We have 926 cell biology PhD Projects, Programmes & Scholarships

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(MCRC Clinical) The role of TIMP-1 in altering the microenvironment of liver metastases

The presence of liver metastasis is associated with poor therapy response and prognosis in multiple cancers. This project will examine how a protein called TIMP-1 affects the liver microenvironment resulting in resistance to immune therapy. Read more
 Supervisors: Dr R Lee, Dr A Hurlstone, Dr S Turajlić, Dr KS Simpson, Mr M Nobis
 23 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Intratumoral heterogeneity in cellular response to p53 and ISR activation

Doctoral study program. Biomedical Sciences. Form. doctoral (present). Department. Department of Biology. Supervisor. Zdenek Andrysik, Ph.D. Read more
 Supervisor: Dr Z Andrysík
 30 November 2026  PhD Research Project  Funded PhD Project (Students Worldwide)
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Causes of clonal expansions of blood stem cells

Causes of clonal expansions of blood stem cells. During ageing, blood stem cell clones expand, increasing the risk of blood cancer and cardiovascular disease, yet most expansions lack known driver mutations. Read more
 Supervisor: Dr L Velten
 22 November 2026  PhD Research Project  Funded PhD Project (Students Worldwide)
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Identifying and modifying the cellular basis of osteoarthritis progression (Botnar-2026-10)

Knee osteoarthritis (OA) is the most common form of arthritis, affecting 5.4 million people in the UK. At advanced stages of disease, OA is characterised by loss of cartilage and inflammation and fibrosis of the synovial tissue that surrounds the joint. Read more
 Supervisors: Assoc Prof S Snelling, Dr J Mimpen
 1 December 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Advancing Drug Delivery for Regeneration and Repair of the Aging Cartilage (Botnar-2026-01)

Drugs targeting biological drivers of aging face unique translational challenges. In this DPhil, a translational strategy targeting an age-associated disease will be leveraged to advance an immediately clinically relevant intervention. Read more
 Supervisors: Dr G Alsaleh, Dr D Carugo, Dr PA Mouthuy
 1 December 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Cancer-related Cognitive Impairment: Investigating neuroimmune mechanisms linking peripheral tumours to dysfunctional synaptic plasticity in the brain

To apply, please contact Dr Graham Sheridan at Graham.Sheridan@nottingham.ac.uk. Project overview. Cancer is increasingly recognised as a systemic disease that produces pathophysiological effects in organs distant from the primary tumour site. Read more
 Supervisor: Dr G Sheridan
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Combining genetic and biophysical approaches to understand the structure function relationship of the Notch Abruptex domain

  Research Group: Division of Evolution, Infection and Genomic Sciences
Notch is a developmental signalling receptor with widespread roles in metazoan development and adult stem cell regulation. Precise control of Notch signalling levels is crucial for proper development and health. Read more
 Supervisors: Dr M Baron, Dr M Cliff, Dr J Swift
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Studying the role of tryptophan imbalance in the oncoviral tumour microenvironment in the context of epigenetic reprogramming

The School of Medicine at the University of Limerick invites applications for a PhD candidate to investigate the role of tryptophan imbalance in shaping the oncoviral tumour microenvironment and driving epigenetic reprogramming in cancer. Read more
 Supervisors: Dr JS Stanley, Prof PM Murray
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Examining the role of IL18R1 and IL18RAP in asthma

  Research Group: Respiratory Sciences
Background. IL-18 is a proinflammatory cytokine though to be involved in the induction and regulation of Type 1 immune responses (1). Read more
 Supervisor: Prof D Cousins
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Long non-coding RNAs and its biological functions

  Research Group: Molecular & Cell Biology
In addition to ~20,000 protein coding genes, human genome contains ~30,000 genes that encode for functional RNAs. Apart from the rRNAs and tRNAs that are involved in translation, the famous example is the Xist RNA involved in silencing of one X chromosome in females. Read more
 Supervisors: Dr O V Makarova, Dr Y Markaki, Dr MT Tellier
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Aldehyde dehydrogenase expression and function in cancer stem cells

Aldehyde dehydrogenases (ALDHs) catalyse the oxidation and detoxification of reactive endogenous and exogenous aldehydes into carboxylic acids via NAD+ coupled reduction. Read more
 Supervisors: Prof K Pors, Dr S Swaroop, Dr A Ruiz Estrada
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Functional mechanisms and inhibition of biomedically important calcium channels

Ion channels are key components in every cell, bridging cell and organellar membranes for the traversal of charged species. Calcium channels are of particular physiological importance because of the central role calcium plays in cell signalling and cell death. Read more
 Supervisors: Prof U Zachariae, Prof R Sknepnek
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Diagnostic biomarkers and mechanistic understanding of biofilm formation in prosthetic joint infection

Applications are invited for a self-funded, 3 year full-time or 6 year part-time PhD project. Read more
 Supervisors: Prof S Robson, Dr R Baldock
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Using stem cells to model the molecular mechanisms of exercise for dementia prevention

Alzheimer’s disease (AD) is the most common cause of dementia, affecting millions worldwide and placing an increasing burden on patients, families and healthcare systems. Read more
 Supervisors: Dr RJ Elsworthy, Prof S Aldred
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Unravelling complex somatic genomic variations: advancing early diagnostics and precision medicine

Complex somatic structural variations (SVs) in genomic regions such as centromeres and telomeres play a crucial role in driving many genetic disorders. Read more
 Supervisors: Assoc Prof SG Garg, Prof D Wedge
 Year round applications  PhD Research Project  Self-Funded PhD Students Only