We have 926 cell biology PhD Projects, Programmes & Scholarships

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cell biology PhD Projects, Programmes & Scholarships

We have 926 cell biology PhD Projects, Programmes & Scholarships

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Studying microRNA landscape during spinal cord regeneration

  Research Group: Division of Molecular and Cellular Function
The human spinal cord (SC) has limited regenerative capacity, and no effective therapies exist to restore function after spinal cord injury (SCI), resulting in severe disability and low quality of life and life-expectancy. Read more
 Supervisors: Dr X Soto Rodriguez, Dr P.S. Slater, Dr K Dorey, Dr A.M. Martín
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Beyond H3K4 Methylation: Mechanistic Insights into How KMT2D Controls Transcription, DNA Repair and Genome Stability

Details of the Project. KMT2D is one of the most frequently mutated genes in human cancer, with recurrent loss-of-function alterations in lymphoma, bladder, colorectal and gastric tumours, and is the causative gene in Kabuki syndrome. Read more
 Supervisors: Dr TK Kantidakis, Dr BK Kysela
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Design, construction and testing of recombinant protein production systems for industrial biotechnology applications.

Details of the Project. The production of recombinant biopharmaceuticals, e.g., antibody fragments and growth hormones, is a billion-dollar industry, with many therapeutic proteins being expressed in the bacterium Escherichia coli [1]. Read more
 Supervisor: Dr DB Browning
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Towards the development of a novel class of broad-spectrum anti-infective drugs

Through exceptionally strong research collaborations at the interface of chemistry, biology, and medicine, we have applied innovative thinking to the field of (Minor Groove Binders) MGBs to develop a novel platform for drug discovery with the potential to treat an impressive range of diseases, including bacterial, fungal, parasitic, and viral infections. Read more
 Supervisor: Dr FS Scott
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Exploiting peptide design in linking hydrogel and spread film properties in the development of novel antibacterial films

  Research Group: Division of Pharmacy and Optometry
This project combines expertise in pharmacy and biotechnology to tune polypeptide/surfactant film properties through the design of novel peptides characterised using advanced physical characterisation techniques and relate the film properties to those of hydrogels. Read more
 Supervisors: Dr R Campbell, Prof A Saiani, Prof A Miller
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Unravelling the Intricacies of Stress Hormone Regulation

Project Overview. The proopiomelanocortin (POMC) pathway is a crucial signaling cascade involved in regulating various physiological processes, including our response to stress, metabolism, immune function, and pigmentation. Read more
 Supervisor: Dr A B Bicknell
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Point-of-care platelet diagnostics

Project Overview. Platelets are small blood cells that play a vital role in the chronic and acute progression of Cardiovascular Disease (CVD), but also have roles in immunity, inflammation, cancer metastasis, Alzheimer's disease and a range of infections, such as dengue, HIV-1, malaria, and COVID-19. Read more
 Supervisor: Dr CI Jones
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Platelets in health, ageing and disease: new diagnostics and treatments

Platelets are small blood cells that play a vital role in the chronic and acute progression of Cardiovascular Disease (CVD), and also have roles in immunity, inflammation, cancer metastasis, Alzheimer's disease and a range of infections, such as dengue, HIV-1, malaria, and COVID-19. Read more
 Supervisor: Dr CI Jones
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Exploring the therapeutic potential of a novel Botulinum toxin

Clostridial neurotoxins are produced by anaerobic bacteria such as Clostridium botulinum. Each toxin molecule has a highly conserved zinc-dependent protease domain that cleaves SNARE proteins, a family of molecules required for intracellular trafficking and vesicle fusion. Read more
 Supervisors: Prof A Peden, Prof J King
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Mechanisms of radiotherapy-induced vascular damage

Radiotherapy is a common treatment for cancer, and is used in over 70% of breast cancer patients. However, radiotherapy is associated with longer term vascular damage including atherosclerosis development and fibrosis. Read more
 Supervisors: Dr K Riches-Suman, Dr J Muller
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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SGLT2 inhibitors and mitochondrial function: a new avenue for an existing drug

  Research Group: Cardiovascular Sciences
Sodium–glucose cotransporter 2 (SGLT2) inhibitors are an established class of antidiabetic drugs that have demonstrated additional benefits beyond glycaemic control, including cardiovascular and renal protection. Read more
 Supervisors: Dr EA Akalestou, Dr LAB Baker
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Development of chemical tools and bioactive compounds to explore the importance of enzyme activity in cancer diseases

Diversity-oriented synthesis (DOS) is a modern chemical methodology, which aims to synthesise small molecules that cover new chemical space with the possibility of finding unexplored biological targets or pathways that may be important for disease progression. Read more
 Supervisors: Prof K Pors, Dr V Jha, Dr Muhammad Wahajuddin
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Molecular mechanisms underlying aphid effector virulence activity

Pests and diseases are a major threat to food security with losses ranging between 20-40%. Aphids are one of the most devastating insect pests, globally. Read more
 Supervisor: Dr J Bos
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Heart failure and fatal epilepsy caused by unbranched glycogen

The accumulation and precipitation of unbranched glycogen in human tissues as toxic polyglucosan bodies (PB) is the cause of cardiomyopathy… Read more
 Supervisors: Prof Sir Philip Cohen, Dr K Swatek
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Identification of the molecular pathways that guide tissue regeneration.

  Research Group: Development, Regeneration and Neurophysiology
The study of regenerative biology aims to elucidate the innate ability of organisms to replace tissues or organs after they have been removed or damaged. Read more
 Supervisor: Dr H Roehl
 Year round applications  PhD Research Project  Self-Funded PhD Students Only