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We have 570 education PhD Projects, Programmes & Scholarships

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education PhD Projects, Programmes & Scholarships

We have 570 education PhD Projects, Programmes & Scholarships

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MSc by Research: Molecular mechanisms underlying aphid effector virulence activity

Pests and diseases are a major threat to food security with losses ranging between 20-40%. Aphids are one of the most devastating insect pests, globally. Read more
 Supervisor: Dr J Bos
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Defying Mendel’s laws: developing tools to understand the principles of epigenetic inheritance in tomato plants

In plants, phenotypic innovation is not exclusively encoded in DNA sequences. Some heritable new traits are associated with modifications on the DNA, such as DNA methylation. Read more
 Supervisor: Dr C Martinho
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Cell migration in epithelial tissues

It is an important question to answer how cells move in a crowded environment.  In this project, we’ll use the vertex model (a widely used computational framework for cell-based studies of epithelial tissue mechanics) to study motion of a small patch of motile cells in otherwise inert environment. . Read more
 Supervisor: Dr R Sknepnek
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Deciphering the ubiquitin codes that regulate protein degradation

Ubiquitin signalling, which involves the posttranslational modification (PTM) of proteins with ubiquitin, regulates almost every aspect of eukaryotic biology. Read more
 Supervisor: Prof Y Kulathu
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Mechanisms of cell size regulation

The tremendous diversity of cell shapes and sizes found in living organisms is fascinating. For instance, cell size differs enormously in the human body with myocytes being about a million-fold larger than red blood cells. Read more
 Supervisors: Dr J Januschke, Dr D H Murray
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Heart failure and fatal epilepsy caused by unbranched glycogen

The accumulation and precipitation of unbranched glycogen in human tissues as toxic polyglucosan bodies (PB) is the cause of cardiomyopathy… Read more
 Supervisors: Prof Sir Philip Cohen, Dr K Swatek
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Greasing plant cell signalling – the role of S-acylation in plant receptor cytoplasmic kinase signalling during immune responses

Protein S-acylation is a reversible fatty acid-based post-translational modification of proteins. Read more
 Supervisors: Dr P Hemsley, Dr J Bos
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Reporting on destruction – developing plant-based assays for PROTAC degrader activity

Protein Targeting Chimera (PROTAC) degraders are small molecules able to recruit a ubiquitin ligase to a protein of interest and promote degradation. Read more
 Supervisors: Dr P Hemsley, Prof A Ciulli, Dr H Drost
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Trimming the fat - Identification of de-S-acylating enzymes from plants

Protein S-acylation is a reversible fatty acid-based post-translational modification of proteins. Read more
 Supervisors: Dr P Hemsley, Dr J Bos
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Role and mechanism of the bacterial Type VI secretion system

Many species of bacteria use a contractile nanomachine known as the Type VI secretion system (T6SS) to deliver a wide range of toxic proteins, known as ‘effectors’, directly into neighbouring cells. Read more
 Supervisor: Dr S Coulthurst
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Identifying microbiota responsible for longevity and health

Gut microbiome is the community of microbes living together in the gastrointestinal tract of an animal. They provide specific functions to the animal host such as digestion of cellulose and protection from invading pathogens. Read more
 Supervisor: Dr V Singh
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Characterisation of human induced pluripotent stem cell derived kidney organoid system for use in drug discovery

Only 5% of all drugs tested in animal models are approved for human applications. Most of these failures are due to unexpected toxicity or lack of efficacy. The poor translation from small mammal studies to humans often causes this challenge. Read more
 Supervisor: Dr PD Davies
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Human heart organoids for drug discovery in heart failure

Study of heart failure and heart attack is extremely difficult. Moreover, only 5% of all drugs tested in animal models are approved for human applications. Read more
 Supervisor: Dr PD Davies
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Investigating Glycogen-Dependent Regulation of Microglia Inflammatory Responses

Microglia are the resident immune cells of the central nervous system, responsible for responding to infection and damage in a protective manner. Read more
 Supervisor: Dr A Lloyd
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Exploring Bacillus biocontrol of Phytophthora raspberry root rot disease

Domestic crop production, increasingly reliant on reduced fertiliser and agrochemical inputs whilst also achieving high yields, is necessary to maintain a high level of food security in the UK. Read more
 Supervisors: Dr A Holmes, Prof N Stanley-Wall
 Year round applications  PhD Research Project  Self-Funded PhD Students Only

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