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education PhD Projects, Programmes & Scholarships

We have 712 education PhD Projects, Programmes & Scholarships

MSc by Research: Deciphering the ubiquitin codes that regulate protein degradation

University of Dundee

Faculty of Life Sciences

Ubiquitin signalling, which involves the posttranslational modification (PTM) of proteins with ubiquitin, regulates almost every aspect of eukaryotic biology. Read more

Supervisor: Prof Y Kulathu

Year round applications PhD Research Project Self-Funded PhD Students Only

MSc by Research: Mechanisms of cell size regulation

University of Dundee

Faculty of Life Sciences

The tremendous diversity of cell shapes and sizes found in living organisms is fascinating. For instance, cell size differs enormously in the human body with myocytes being about a million-fold larger than red blood cells. Read more

Supervisors: Prof J Januschke, Dr D H Murray

Year round applications PhD Research Project Self-Funded PhD Students Only

MSc by Research: Heart failure and fatal epilepsy caused by unbranched glycogen

University of Dundee

Faculty of Life Sciences

The accumulation and precipitation of unbranched glycogen in human tissues as toxic polyglucosan bodies (PB) is the cause of cardiomyopathy… Read more

Supervisors: Prof Sir Philip Cohen, Dr K Swatek

Year round applications PhD Research Project Self-Funded PhD Students Only

MSc by Research: Greasing plant cell signalling – the role of S-acylation in plant receptor cytoplasmic kinase signalling during immune responses

University of Dundee

Faculty of Life Sciences

Protein S-acylation is a reversible fatty acid-based post-translational modification of proteins. Read more

Supervisors: Dr P Hemsley, Dr J Bos

Year round applications PhD Research Project Self-Funded PhD Students Only

MSc by Research: Reporting on destruction – developing plant-based assays for PROTAC degrader activity

University of Dundee

Faculty of Life Sciences

Protein Targeting Chimera (PROTAC) degraders are small molecules able to recruit a ubiquitin ligase to a protein of interest and promote degradation. Read more

Supervisors: Dr P Hemsley, Prof A Ciulli, Dr H Drost

Year round applications PhD Research Project Self-Funded PhD Students Only

MSc by Research: Trimming the fat - Identification of de-S-acylating enzymes from plants

University of Dundee

Faculty of Life Sciences

Protein S-acylation is a reversible fatty acid-based post-translational modification of proteins. Read more

Supervisors: Dr P Hemsley, Dr J Bos

Year round applications PhD Research Project Self-Funded PhD Students Only

MSc by Research: Role and mechanism of the bacterial Type VI secretion system

University of Dundee

Faculty of Life Sciences

Many species of bacteria use a contractile nanomachine known as the Type VI secretion system (T6SS) to deliver a wide range of toxic proteins, known as ‘effectors’, directly into neighbouring cells. Read more

Supervisor: Prof S Coulthurst

Year round applications PhD Research Project Self-Funded PhD Students Only

MSc by Research: Identifying microbiota responsible for longevity and health

University of Dundee

Faculty of Life Sciences

Gut microbiome is the community of microbes living together in the gastrointestinal tract of an animal. They provide specific functions to the animal host such as digestion of cellulose and protection from invading pathogens. Read more

Supervisor: Dr V Singh

Year round applications PhD Research Project Self-Funded PhD Students Only

MSc by Research: Characterisation of human induced pluripotent stem cell derived kidney organoid system for use in drug discovery

University of Dundee

Faculty of Life Sciences

Only 5% of all drugs tested in animal models are approved for human applications. Most of these failures are due to unexpected toxicity or lack of efficacy. The poor translation from small mammal studies to humans often causes this challenge. Read more

Supervisor: Dr PD Davies

Year round applications PhD Research Project Self-Funded PhD Students Only

MSc by Research: Human heart organoids for drug discovery in heart failure

University of Dundee

Faculty of Life Sciences

Study of heart failure and heart attack is extremely difficult. Moreover, only 5% of all drugs tested in animal models are approved for human applications. Read more

Supervisor: Dr PD Davies

Year round applications PhD Research Project Self-Funded PhD Students Only

MSc by Research: Investigating Glycogen-Dependent Regulation of Microglia Inflammatory Responses

University of Dundee

Faculty of Life Sciences

Microglia are the resident immune cells of the central nervous system, responsible for responding to infection and damage in a protective manner. Read more

Supervisor: Dr A Lloyd

Year round applications PhD Research Project Self-Funded PhD Students Only

MSc by Research: Exploring Bacillus biocontrol of Phytophthora raspberry root rot disease

University of Dundee

Faculty of Life Sciences

Domestic crop production, increasingly reliant on reduced fertiliser and agrochemical inputs whilst also achieving high yields, is necessary to maintain a high level of food security in the UK. Read more

Supervisors: Dr A Holmes, Prof N Stanley-Wall

Year round applications PhD Research Project Self-Funded PhD Students Only

MSc by Research: Investigation of mitochondrial biology and neurodegeneration

University of Dundee

Faculty of Life Sciences

Phosphorylation and ubiquitylation are reversible signalling events and there is significant interest in in their interplay in the regulation… Read more

Supervisor: Prof M Muqit

Year round applications PhD Research Project Self-Funded PhD Students Only

MSc by Research: Targeting ‘Undruggable’ Oncoproteins via Induced Proximity

University of Dundee

Faculty of Life Sciences

Many well-established cancer drivers, such as K-Ras and β-catenin, have long been considered ‘undruggable’, as traditional drug development approaches have failed to effectively inhibit their activity. Read more

Supervisors: Prof G Sapkota, Dr S Virdee

Year round applications PhD Research Project Self-Funded PhD Students Only

MSc by Research: Functional mechanisms and inhibition of biomedically important calcium channels

University of Dundee

Faculty of Life Sciences

Ion channels are key components in every cell, bridging cell and organellar membranes for the traversal of charged species. Calcium channels are of particular physiological importance because of the central role calcium plays in cell signalling and cell death. Read more

Supervisors: Prof U Zachariae, Prof R Sknepnek

Year round applications PhD Research Project Self-Funded PhD Students Only

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