We have 84 mathematical biology PhD Projects, Programmes & Scholarships

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mathematical biology PhD Projects, Programmes & Scholarships

We have 84 mathematical biology PhD Projects, Programmes & Scholarships

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Age-related disease: Fidelity mechanisms that protect against epigenetic decay

Lead supervisor. Prof Dawn Coverley. Co-supervisors. Dr Andrew Mason. The student will be registered with the Department of Biology. Read more
 Supervisors: Prof D Coverley, Dr A Mason
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Understanding modes of AB toxin virulence and host defence mechanisms

Lead supervisor. Dr Chris MacDonald. Co-supervisors. Dr Martin Fascione and Dr C Spicer. The student will be registered with the Department of Biology. Read more
 Supervisors: Dr C MacDonald, Dr M A Fascione, Dr C Spicer
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Role of stem cell-derived extracellular vesicles in immune cell function; clinical development of a new biotherapeutic

Lead supervisor. Prof Paul Genever. Co-supervisors. Dr Ioannis Kourtzelis. The student will be registered with the Department of Biology. Read more
 Supervisors: Prof P Genever, Dr I Kourtzelis
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Elucidating the mechanisms of pathology in neurodevelopmental white matter diseases

Lead supervisor. Dr Noemie Hamilton. The student will be registered with the Department of Biology. Our research interests are to dissect the mechanism of auto-inflammatory neurological disorders using zebrafish as an animal model. Read more
 Supervisor: Dr N Hamilton
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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A multi-modal approach to study acute myeloid leukaemia

Lead supervisor. Dr William Grey. Co-supervisors. Dr Anjum Khan. The student will be registered with the Department of Biology. Acute myeloid leukaemia (AML) remains the most lethal blood cancer, with long-term survival under 10% in older patients. Read more
 Supervisors: Dr W Grey, Dr A Khan
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Water and the biology of structure of articular cartilage

Articular cartilage (AC) is composed of ~70% water by weight. The rules for life for this critical constituent of AC are poorly understood, and often overlooked experimentally. Read more
 Supervisors: Dr D Espino, Dr A Mahomed
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Eastbio: Mechanism and consequences of lethal zygosis in bacteria restricting AMR plasmids.

Antimicrobial resistance (AMR) is a major public health crisis, largely due to the carriage of AMR genes on conjugative plasmids, mobile genetic elements that spread by conjugation between bacteria. Read more
 Supervisors: Dr T Dimitriu, Prof M F White
 16 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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EASTBIO Unravelling the Regulation of Small RNAs in the Prostate

  Research Group: Statistical Medicine and Molecular Biology
Aside from messenger RNA (mRNA), a whole raft of small non-coding RNAs are at work in the cell, but these have been relatively neglected in studies of genetic and epigenetic regulation. Read more
 Supervisors: Prof A Lynch, Dr G Minas
 16 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Deep learning of nascent transcription dynamics to predict mature mRNA production

  Research Group: Molecular & Cell Biology
The production of mature messenger RNA (mRNA) from a human protein-coding gene is a highly regulated process involving transcription by RNA polymerase II (RNAPII) and co-transcriptional RNA processing, including splicing and cleavage/polyadenylation. Read more
 Supervisors: Dr MT Tellier, Dr MA Cavallaro
 23 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Revealing the correlation between physiology and physical chemistry of microcalcification in connective tissue using AI supported tissue characterization.

  Research Group: Healthcare Engineering
A fundamental component of human body is connective tissue which serves various structural and supportive functions including skin integrity, abdominal wall enforcement and bone formation. Read more
 Supervisors: Dr M Chauhan, Dr R Kroger
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Systems Biology of Airway Mucus Clearance: An Integrated Experimental and Computational Approach

  Research Group: Respiratory Sciences
Phlegm lines our airways, traps dust and germs and is essential to keep our lungs healthy. Coughing creates airflow that pushes phlegm out. Read more
 Supervisors: Dr E Gaillard, Dr E Abo-Serie
 23 November 2026  PhD Research Project  Funded PhD Project (Students Worldwide)
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Network archaeology in random trees (S3.5-MPS-Lodewijks)

A fully funded PhD opportunity to participate in the world-leading research undertaken by the EPSRC Doctoral Landscape Award at the University of Sheffield. Read more
 Supervisors: Dr B Lodewijks, Dr J Jordan
 13 January 2027  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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EASTBIO: What determines whether a resistance plasmid establishes and spreads in a new bacterial lineage?

Antibiotic resistance genes are frequently carried on plasmids, which spread horizontally between bacteria and vertically through expansion of successful resistant clones. Read more
 Supervisors: Prof K Atkins, Dr T Schneiders
 16 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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EASTBIO: Decoding Volume Regulation Across Timescales with Ultrafast imaging and Mechanistic Modelling

Cell volume is fundamental to biological organisation, controlling molecular concentration, intracellular transport, membrane tension and cytoplasmic mechanics. Read more
 Supervisors: Dr P Bagnaninchi, Dr C G Hansen
 16 November 2026  PhD Research Project  Funded PhD Project (Students Worldwide)
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EASTBIO: Discovering the rules of stem cell self-organisation with AI-guided experimental design

What if we could watch groups of cells organise themselves into a tissue and automatically learn the rules by which these cells coordinate with each other? And what if we can then use those rules to optimise future experiments? In this project you will build the computational methods to achieve that. Read more
 Supervisors: Dr L Schumacher, Dr G Blin
 16 November 2026  PhD Research Project  Funded PhD Project (Students Worldwide)