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medicine PhD Projects, Programmes & Scholarships

We have 535 medicine PhD Projects, Programmes & Scholarships

(MCRC Non-Clinical) Exploiting Chromosomal Instability Across the Ovarian–Endometrial Axis: Models, Mechanisms and Therapeutic Targeting

The University of Manchester

Division of Cancer Sciences

The most aggressive ovarian and endometrial cancers converge on a common phenotype. extensive chromosomal instability (CIN) – ongoing chromosomal changes that generate karyotypic heterogeneity within a tumour, linked to poor patient outcomes. Read more

Supervisors: Dr BB Barnes, Prof S Taylor, Dr SK Kitson

23 November 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

(MCRC Non-Clinical) Unlocking the power of Geographic Information Systems for Breast Cancer Risk and Prevention

The University of Manchester

Division of Informatics, Imaging and Data Sciences

At least 30% of breast cancer risk is unexplained by current risk prediction algorithms which incorporate family history, personal history of benign breast disease, polygenic risk scores, breast density, hormonal and reproductive factors, lifestyle and demographic information. Read more

Supervisors: Prof S Astley, Dr SH Howell, Dr EH Harkess, Dr SR Romanov

23 November 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

(MCRC Non-Clinical) Development of a UK proton computed tomography system

The University of Manchester

Division of Cancer Sciences

The advantage of proton beam therapy over conventional X-ray radiotherapy is the increased normal tissue sparing. This advantage, however, is impacted by beam delivery accuracy which, in turn, is impacted by the associated uncertainties. Read more

Supervisors: Dr M Taylor, Dr AA Aitkenhead

23 November 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

(MCRC Non-Clinical) Enhancing liquid biopsy with nanoparticles for the detection of oesophageal carcinoma

The University of Manchester

Division of Cancer Sciences

Liquid biopsies have the potential to transform cancer care by enabling tumour detection and monitoring through a simple blood sample. Read more

Supervisors: Dr FM Mouliere, Dr MH Hadjidemetriou, Dr SV Valpione, Dr A Clipson

23 November 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

(MCRC Non-Clinical) Personalising Prostate Cancer Radiotherapy Using Imaging and Genomic Biomarkers

The University of Manchester

Division of Cancer Sciences

Radiotherapy is an effective treatment for prostate cancer, but men vary widely in their susceptibility to radiation-induced side effects. Read more

Supervisors: Dr JS Shortall, Dr A McWilliam, Prof AC Choudhury

23 November 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

(MCRC Non-Clinical) Investigating the role of heterogeneity and plasticity in small cell lung cancer invasion

The University of Manchester

Division of Cancer Sciences

Small cell lung cancer (SCLC) is among the most aggressive cancers. Approximately 80% of patients present with metastatic disease at which stage treatment options are limited, and median survival <1 year. Read more

Supervisors: Dr M Baker, Prof A Malliri, Dr K Simpson, Dr Colin Lindsay, Prof C Dive

23 November 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

(MCRC Non-Clinical) Elucidating progesterone-driven Wnt signalling for breast cancer prevention

The University of Manchester

Division of Cancer Sciences

Progesterone signalling is essential for normal breast development, but repeated hormone-driven expansion of progenitor cells may also create cellular states that initiate breast tumours. Read more

Supervisors: Dr B Simoes, Prof R Clarke, Dr S Nagarajan, Dr SH Howell

23 November 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

(MCRC Clinical) From niche to clone: linking stromal–immune ecosystems to metastatic evolution in penile cancer

The University of Manchester

Division of Cancer Sciences

Penile squamous cell carcinoma is a rare cancer in which spread to the lymph nodes is the major determinant of survival. Yet we still cannot reliably identify which primary tumours will metastasise, meaning many patients undergo invasive nodal staging without metastatic disease being found. Read more

Supervisors: Prof VJ Sangar, Prof R Bristow, Dr A Virós, Dr A Sachdeva

23 November 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

(MCRC Clinical)Shaping early post-transplant inflammation to strengthen graft-versus- leukaemia

The University of Manchester

Division of Cancer Sciences

Allogeneic stem cell transplantation is the only cure for most patients with high-risk acute myeloid leukaemia. It works because donor immune cells recognise and destroy residual leukaemia, an effect known as graft-versus-leukaemia (GvL). Read more

Supervisors: Dr MW Williams, Prof RW Wynn, Prof T Somervaille

23 November 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

(MCRC Clinical) An integrated digital pathology and functional tissue study of risk stratification in penile squamous cell carcinoma

The University of Manchester

Division of Cancer Sciences

Penile squamous cell carcinoma (PSCC) is a rare malignancy in which surgery is the main treatment modality. However, patients suffer substantial physical, psychological and sexual morbidity. Read more

Supervisors: Prof R Bristow, Dr A Sachdeva, Prof P Hoskin, Dr PO Oliveira, Dr AP Parnham

23 November 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

(MCRC Clinical) Sustaining adoptive T cell immunity: defining the role of activated dendritic cells in solid tumours

The University of Manchester

Division of Cancer Sciences

Adoptive cellular therapies, in which tumour-reactive T cells are expanded or engineered before being transferred into patients, have transformed the treatment of some blood cancers and are showing increasing promise in solid tumours. Read more

Supervisors: Prof SZ Zelenay, Dr JL Lim

23 November 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

(MCRC Clinical) The role of TIMP-1 in altering the microenvironment of liver metastases

The University of Manchester

Division of Cancer Sciences

The presence of liver metastasis is associated with poor therapy response and prognosis in multiple cancers. This project will examine how a protein called TIMP-1 affects the liver microenvironment resulting in resistance to immune therapy. Read more

Supervisors: Dr R Lee, Dr A Hurlstone, Dr S Turajlić, Dr KS Simpson, Mr M Nobis

23 November 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

(MCRC Clinical) REACH – Radiation Effects to Auditory, Cognition and Hormone profile in childhood brain tumour survivors

The University of Manchester

Division of Cancer Sciences

Radiotherapy remains pivotal in curing paediatric brain tumours, but survivors can face significant, life-changing late effects, e.g. Read more

Supervisors: Dr M McCabe, Dr M Aznar, Dr SP Pan, Dr J/l Littlejohn

23 November 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

Investigating the interaction of La related proteins with colliding ribosomes

The University of Manchester

Division of Molecular and Cellular Function

Research Group: Division of Molecular and Cellular Function

How do cells keep making the right proteins when conditions become stressful? Protein synthesis is one of the most fundamental processes in biology, yet ribosomes do not move smoothly along every mRNA. Read more

Supervisors: Prof G D Pavitt, Dr A Roseman

Year round applications PhD Research Project Self-Funded PhD Students Only

Visualising How Cells Regulate Protein Synthesis During Stress

The University of Manchester

Division of Molecular and Cellular Function

Research Group: Division of Molecular and Cellular Function

How do cells decide when and how much of each protein to make? This PhD project will investigate this fundamental question by studying the integrated stress response, a pathway that allows cells to adapt when conditions change. Read more

Supervisors: Prof G D Pavitt, Prof M Ashe, Dr A Roseman

Year round applications PhD Research Project Self-Funded PhD Students Only

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