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We have 336 medicine PhD Projects, Programmes & Scholarships

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medicine PhD Projects, Programmes & Scholarships

We have 336 medicine PhD Projects, Programmes & Scholarships

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Investigating the role of Post-Translational Modifications in Mcl-1 in macrophage host defense against bacteria in chronic lung disease

Regulation of Mcl-1 in Macrophage Host Defense. This PhD project offers an opportunity to explore immunometabolism and cell signaling, focusing on how macrophages decide whether to live or die to protect the host. Read more
 Supervisors: Dr H Marriott, Dr J Cole
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Dental implications of GLP-1 receptor obesity medicines

The study of the oral effects of medications is of utmost importance in an aging multi-morbid yet dentate population. Obesity treatment medicines such as GLP-1 receptor agonists Wegovy and Mounjaro are now widely prescribed due to the high prevalence of metabolic syndrome in the UK and beyond. Read more
 Supervisors: Prof K Hijazi, Dr J Smith, Prof L Heisler
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Elucidating the Immunomodulatory Role of NME4 in Macrophage and Neutrophil Responses using Zebrafish (Danio rerio)

Mitochondria are not only the powerhouses of the cell but also key regulators of innate immunity, influencing processes such as inflammasome activation, reactive oxygen species (ROS) production, and metabolic reprogramming. Read more
 Supervisors: Prof S Renshaw, Dr R Muimo
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Understanding the contribution of SHANK3 LLPS in autism and cancer

  Research Group: Division of Cell Matrix Biology and Regenerative Medicine
In this exciting research project, you will investigate SHANK3, a key protein that facilitates communication and adaptation in brain cells. Read more
 Supervisors: Dr TZ Zacharchenko, Dr IB Barsukov, Prof S Kimber
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Skin Regeneration: Mechanisms and Therapeutic Opportunities

  Research Group: Division of Cell Matrix Biology and Regenerative Medicine
Healthy skin depends on strong adhesion between the cells of the upper layers of epidermis and the underlying dermis. When these attachment fails, as in trauma, chronic wounds or inherited blistering disorders, patients suffer from recurrent infections, impaired healing, and pain. Read more
 Supervisors: Dr S Kurinna, Dr P Hiebert, Dr C Ballestrem
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Understanding how low UPF1 expression leads to drug resistance in bladder cancers

Currently, standard of care for muscle invasive bladder cancer after surgery involves radiation and platinum therapy in combination with other DNA damage-inducing agents and replication inhibitors [8]. Read more
 Supervisors: Dr R Thompson, Prof S Hussain
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Development of new mRNA-based cancer vaccines for breast cancer

Applications are invited for a self-funded, 3 year full-time or 6 year part-time PhD project. The PhD will be based in the School of Medicine, Pharmacy and Biomedical Sciences and will be supervised by Dr Roja Hadianamrei and Dr Sassan Hafizi. . Read more
 Supervisors: Dr R Hadianamrei, Dr S Hafizi
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Case-specific prediction of BH3-mimetic responses in cancer patients using an integrated experimental and computational quantitative systems pharmacology approach

Applications are invited for a self-funded, 3 year full-time or 6 year part-time PhD project. The PhD will be based in the School of Medicine, Pharmacy and Biomedical Sciences and will be supervised by Dr Gavin Fullstone. Read more
 Supervisor: Dr G Fullstone
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating Catecholamine Signalling in Human Pancreatic Islets- A New Target for Diabetes Therapy

Applications are invited for a self-funded, 3 year full-time or 6 year part-time PhD project. The PhD will be based in the School of Medicine, Pharmacy and Biomedical Sciences and will be supervised by Dr Despoina Aslanoglou and Dr Tony Lewis. Read more
 Supervisors: Dr D Aslanoglou, Dr A Lewis
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Uncovering the molecular mechanisms underlying spinal cord regeneration

Motor nerves connect the spinal cord and brain with muscles in our face, arms, legs and internal organs. The motor nerves send signals which tell these muscles to contract. Read more
 Supervisors: Dr K Dorey, Dr N Roberts
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Functional Mechanisms of Genetic Risk Factors for Immune-Related Disease

Who are we?. Read more
 Supervisor: Prof T Vyse
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Development of a bioink to enable bioprinting of stromal tissue mimics

Human tissues are complex architectures made up of a combination of cells spatially organised within distinct matrices. Cells make and maintain this matrix, through which they receive biochemical, mechanical, and topological stimuli that are crucial to establish and maintain tissue function. Read more
 Supervisors: Dr J Swift, Dr A Gilmore, Dr E Skaria
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Physiology and mathematical modelling of pharmacodynamics in the human placenta

Medicines regulators are calling for new alternative methods to replace animal testing of in the safety evaluation of pharmaceuticals prescribed to women of childbearing age. Read more
 Supervisors: Dr P Brownbill, Dr E Doman
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the connection between early embryo architecture and embryo viability

In humans, approximately a quarter of all pregnancies end before 6 weeks’ gestation, often around the time of implantation, before the pregnancy has become apparent. Read more
 Supervisors: Dr B Plusa, Dr K Dorey
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Modulation of Smooth Muscle Cell Function by Neutrophil Microvesicles

The leading cause of death globally is cardiovascular disease (CVD), according to the World Health Organisation. Atherosclerosis is the underlying cause of most of these. Read more
 Supervisors: Dr V Ridger, Prof S Francis
 Year round applications  PhD Research Project  Self-Funded PhD Students Only

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