We have 178 MRC PhD Projects, Programmes & Scholarships

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MRC PhD Projects, Programmes & Scholarships

We have 178 MRC PhD Projects, Programmes & Scholarships

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Towards Precision Psychiatry: Early Detection and Intervention in Schizophrenia

Cardiff University
Cardiff School of Pharmacy and Pharmaceutical Sciences
Schizophrenia affects around 1% of the population and remains one of the most challenging mental health disorders to predict and treat. Read more
 Supervisors: Dr M Heurich-Sevcenco, Dr M Bassetto
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Sweet disposition: combatting bacterial infections and antimicrobial resistance with designer proteins that target biofilm matrix carbohydrates

Cardiff University
Cardiff School of Pharmacy and Pharmaceutical Sciences
Microorganisms grow as biofilms on surfaces, from teeth to surgical implants or even the lining of the lungs. Biofilms are dense cell aggregates embedded in a complex matrix of molecules that surrounds and protect the cells. Read more
 Supervisor: Dr F Parmeggiani
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Silent Architects: Uncovering How Astrocytes Shape Brain Health

Cardiff University
Cardiff School of Medicine
Summary. Astrocytes are central regulators of brain function, controlling neuronal activity, metabolism, extracellular matrix organisation and resilience to disease. Read more
 Supervisors: Dr G Smith, Prof BSK Khakh, Dr O Peters, Prof J Hodge
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Guarding the Brain's Blueprint: Investigating UPF3B in DNA Repair, Autism, and ADHD

Cardiff University
Cardiff School of Medicine
Summary. Neurodevelopmental disorders (NDDs) like autism and ADHD affect millions, yet the underlying causes remain unclear. This PhD project investigates how mutations in the gene UPF3B, linked to NDDs, impair DNA repair in neurons. Read more
 Supervisors: Dr GN Ngo, Prof N Allen
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Power Failure: Why Neurons Die in Huntington's Disease

Cardiff University
Cardiff School of Medicine
Summary. Huntington's disease is an inherited brain disorder that causes progressive movement, cognitive and sleep problems, yet there is still no effective treatment. Read more
 Supervisors: Dr T Massey, Dr G Smith, Dr M Lelos, Prof J Hodge
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Investigating placental function and fetal programming in Prader–Willi Syndrome

Cardiff University
Cardiff School of Medicine
Summary. By bringing together transcriptomics and cutting edge imaging, and data analysis techniques, this PhD project aims to examine how abnormalities in placental function leads to altered programming of the developing fetal brain in a neurodevelopmental disorder. Read more
 Supervisors: Prof A R Isles, Prof R John
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Finding the Earliest Signs of Psychosis: Studying Young People at High Genetic Risk

Cardiff University
Cardiff School of Medicine
Summary. Why do some young people develop psychosis while others do not? This project will investigate the developmental origins of psychosis in young people at high genetic risk. Read more
 Supervisors: Dr SC Chawner, Prof M van den Bree, Dr JH Hall
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Shared Genetic Architecture of Neuropsychiatric Disorders and Novel Brain Biomarkers: Towards Understanding Biological Processes

Cardiff University
Cardiff School of Medicine
Summary. The field of imaging genetics has had limited success identifying shared common risk variants between mental disorders and brain phenotypes, this being key to understanding neurobiological mechanism for ill mental health. Read more
 Supervisors: Dr X Caseras, Dr M Palombo, Prof K Murphy, Dr R Anney
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Optimising immune responses against emerging viruses

Cardiff University
Cardiff School of Medicine
Summary. Worldwide, viruses that transmit to humans from biting insects account for ~17% of infectious diseases and ~700,000 deaths/yr, with ~4 billion people at risk. Read more
 Supervisors: Prof R Stanton, Dr C Fielding, Dr E Wang
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Receptor to Remedy: Rewiring adenovirus-host protein dynamics to engineer next-generation nanomedicines.

Cardiff University
Cardiff School of Medicine
Summary. How do viruses hijack our cells, and how can we turn this process to our advantage? This project will explore the fascinating molecular interactions between viruses and human cells, uncovering how viruses recognise, enter and manipulate their hosts. Read more
 Supervisors: Prof AP Parker, Dr C Bliss, Dr V Gold
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Immune modulation of tonsillar Natural Killer cell immunity by Group A Streptococcus

Cardiff University
Cardiff School of Medicine
Summary. The human tonsils are crucial for producing neutralizing antibodies against infection yet are a breeding ground for Group A Streptococcus (GAS) which causes localized illnesses (tonsillitis) but also life threatening, invasive infections (>500,000 global deaths/year). Read more
 Supervisors: Dr J McLaren, Dr E Wang
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Understanding cellular ageing of protective immunity to inform vaccine design and T-cell therapies

Cardiff University
Cardiff School of Medicine
Summary. The risk of dying from infection is particularly high in the elderly and is related to ageing of the immune system. Immune cells called T-cells can confer long-term protection against infection and hence are critical for vaccine development. Read more
 Supervisors: Dr KL Ladell, Prof L Wooldridge, Prof D Baird, Prof D Price
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Investigation of human cytomegalovirus modulation of gamma delta Tcells

Cardiff University
Cardiff School of Medicine
Summary. Immune cells are important for the control of viral infections. In particular, innate cytotoxic lymphocytes such as gamma delta T-cells and natural killer (NK) are able to sense healthy tissue and kill tumour and viral-infected cells. Read more
 Supervisors: Dr C Fielding, Dr E Wang, Prof R Stanton
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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