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PhD Projects, Programmes & Scholarships

We have 5,850 PhD Projects, Programmes & Scholarships

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Sustained Release of Eutectic systems composed of Local Anaesthetics and non-steroidal anti-inflammatory agents from biodegradable electrospun mats to Enhance Post-Surgical Recovery

Major abdominal surgery is a metabolically and psychologically significant event associated with prolonged recovery and convalescence. Read more
 Supervisor: Prof D Jones
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Transforming Drug Delivery: AI and Machine Learning in Design, Optimization, and Personalization

This research explores the transformative role of digital technologies, particularly machine learning, microfluidics, and bioprinting, in advancing pharmaceutical design and therapeutic delivery. Read more
 Supervisor: Prof D Lamprou
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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VAPShield: Development of next-generation endotracheal tube materials for the prevention of ventilator-associated pneumonia

Critically ill patients often depend on life-saving devices such as breathing tubes, called endotracheal. tubes (ETTs), to help them breathe when they cannot do so on their own. Read more
 Supervisors: Dr M Wylie, Prof C McCoy
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Next-Generation High-level Disinfectants: Targeting Bacterial Persistence on Medical Surfaces

This PhD project explores the development and mechanistic evaluation of advanced disinfection technologies targeting bacterial spores and biofilm-forming pathogens on hard surfaces and medical devices. Read more
 Supervisors: Dr M Wylie, Prof C McCoy
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Next-Gen Drug Delivery: Microfluidic Encapsulation of Biologics into Smart Nanocarriers

Provide a brief description of the project. Progress in drug design has led to the development of new peptides, proteins, and drug molecules. Read more
 Supervisor: Prof D Lamprou
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Multipurpose gel formulations containing antiretroviral-loaded lactoferrin nanoparticles and antibiotics for combination HIV prevention and treatment of bacterial vaginosis

Summary descriptive text / Example of research project  . Lactoferrin . Lactoferrin is a multifunctional globular protein. Read more
 Supervisors: Dr S Carmali, Prof K Malcolm
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Microfluidic Encapsulation of biologics into Nanomedicines

Progress in drug design has led to the development of new peptides, proteins, and drug molecules. However, the limited ability to deliver selectively these molecules at well-defined dosing regimens and without invoking drug-resistance remains a significant challenge. Read more
 Supervisor: Prof D Lamprou
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Medicines optimisation in palliative and end of life care

  Research Group: Healthcare delivery and medicines optimisation
Medicines optimisation at the end of life is essential in palliative and end of life care, where the priority shifts from disease treatment to enhancing quality of life and minimising harm. Read more
 Supervisor: Dr C Parsons
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Infection-responsive coatings for the prevention of catheter-associated urinary tract infections

Medical care has transformed over the last century with significant improvements in the variety and extent to which various diseases can be treated and/or prevented. Read more
 Supervisor: Dr M Wylie
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Formulation of hybrid peptide-lipid nanoparticle formulations for targeted nucleic acid delivery

The project aims to develop next-generation delivery systems that combine the structural advantages of lipid nanoparticles with the targeting and membrane-translocating properties of peptides. Read more
 Supervisors: Dr E McErlean, Dr V Kett
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Development of silicone-based personal lubricant products containing antiretroviral drugs for prevention of sexual acquisition of HIV infection

​​Three drug products are now available to prevent HIV prevention: . ​Truvada®/ Descovy®—daily oral pills containing the antiretroviral drugs emtricitabine and tenofovir  . Read more
 Supervisor: Prof K Malcolm
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Development of dual-functional antibacterial and antifungal polymers to prevent medical device-associated infections

Medical device-related fungal infections caused by Candida spp., e.g., in urinary catheters, account for 17.8% of catheter-associated urinary tract infections, posing significant health risks, especially in individuals with compromised immunity. Read more
 Supervisor: Dr SZ Zhang
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Developing novel therapeutic strategies to better treat Triple Negative Breast Cancer

One in two people will develop cancer in their lifetime and it is a leading cause of death. While significant progress has been made in the treatment of some cancers, there still remain some forms of the disease with limited treatment options and poor outcome. Read more
 Supervisor: Dr N Buckley
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Developing cost-effective and eco-friendly antiviral nano-agents

Humans have been fighting viruses throughout history, from smallpox, Ebola, HIV to SARS, MERS and Zika, which have costed billions of lives and made severe socio-economic impacts irreversibly. Read more
 Supervisor: Dr YG Ge
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Developing and characterising novel targeted nanocomposites serving as adjuvants to existing standard-of-care cancer treatments

One in two cancer patients will receive radiotherapy as part of their standard-of-care treatment. For patients with a localised cancer diagnosis effective radiotherapy represents the best chance for a curative outcome but is not without risk. Read more
 Supervisor: Dr J Coulter
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Design and Evaluation of an eye-on-a-chip Microfluidic Device

With the increasing prevalence of debilitating eye diseases such as age-related macular degeneration, glaucoma, and dry-eye syndromes, there is a pressing need for the development of novel therapeutic strategies. Read more
 Supervisor: Prof D Lamprou
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Biomaterial coatings with lubricious, slippery coatings for improved urinary catheter performance

Intermittent urinary catheterisation is commonly used to address chronic urinary retention in patients suffering from conditions such as spinal cord injury, stroke, and multiple sclerosis. Read more
 Supervisor: Dr M Wylie
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Bioactive, biodegradable coatings for urinary medical devices

The incidence of infection associated with indwelling medical devices is considerable and increases with the dwell time and location of the device. … Read more
 Supervisor: Prof D Jones
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Bacteriophage-derived antimicrobial proteins

Antimicrobial resistance is a global health challenge and there is an urgent need for precision antimicrobials that can eradicate pathogens and biofilms without driving broad-spectrum resistance. Read more
 Supervisors: Dr T Skvortsov, Dr S Carmali
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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A novel top-down approach to produce super small drug nanocrystals to target intracellular organelles

Would you like to join a highly dynamic, international research group to develop super small drug nanocrystals (NCs)? In this project, you will develop drug NCs of ~100 nm to target intracellular organelles. Read more
 Supervisor: Dr A Paredes
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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4D printed Biomaterials in cancer therapeutics

According to WHO, cancer is the second leading cause of death worldwide, with nearly 1 in 6 deaths been due to cancer. The principal modes of cancer management are surgery, radiotherapy, chemotherapy and pharmaceutical agents. Read more
 Supervisor: Prof D Lamprou
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The role of general practice pharmacists in supporting medicines use by people living with dementia

Medicines are a cornerstone of chronic disease management, including for people living with dementia (PLWD), who frequently experience polypharmacy and complex medication regimens. Read more
 Supervisors: Dr H Barry, Prof C Hughes
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Microneedle-mediated Intradermal Delivery: Potential for Lymphatic Targeting of Therapeutic Agents

Though immunotherapy has revolutionized the treatment of cancer to improve disease outcomes, an array of challenges remain that limit wider clinical success, including low rate of response and immune-related adverse events. Read more
 Supervisors: Prof R Donnelly, Dr A Paredes
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Modulating the Gut Microbiome to Reduce Infection Risk

Infection development, including surgical site infections (SSI) and urinary tract infections (UTI), remains a major cause of morbidity, prolonged hospital stay, and antimicrobial use. Read more
 Supervisors: Dr S Kelly, Dr T Skvortsov
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Novel, rheologically-structured implants for the prevention/treatment of bovine mastitis

Bovine mastitis has already been recognized as one of the most serious problems that affects milk production and quality, resulting in large financial losses to dairy farmers. Read more
 Supervisors: Prof D Jones, Prof G Andrews
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Cutting to the Core: Mechanistic Dissection of Nuclear Protease Function in Tumour Biology

Proteases are classically viewed as degradative enzymes that function in the cytoplasm or extracellular space. Emerging evidence reveals a surprising role for specific proteases within the nucleus, where they influence key processes such as chromatin remodelling, transcriptional control, and DNA repair. Read more
 Supervisors: Dr R Burden, Dr J Burrows
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Development of Nano-Liposome Based Drug Delivery Systems for Ocular Diseases

Ocular drug delivery presents one of the greatest challenges in pharmaceutical science, largely due to the eye’s unique anatomy, which limits drug permeation to the intended site of action. Read more
 Supervisors: Prof R Thakur, Dr LV Vora
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Design and Assessment of Innovative Long-Acting Drug Delivery System

Current clinical therapies often rely on intermittent drug administration, such as frequent oral tablets or injections, as seen in diabetes management. Read more
 Supervisors: Prof R Thakur, Prof D Jones
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Development and Evaluation of Microneedle Arrays for Ocular Drug Delivery

Minimally invasive microneedles (MNs) offer unique opportunities to address current challenges in the effective management of ocular disorders, such as age-related macular degeneration and diabetic retinopathy. Read more
 Supervisors: Prof R Thakur, Prof R Donnelly
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Development of Peptide-Based Nanomicelle Eye Drops for the Treatment of Dry Eye Disease

Ocular drug delivery remains a major challenge due to the eye’s complex anatomy and dynamic protective barriers that restrict drug absorption. Read more
 Supervisors: Prof R Thakur, Prof D Jones
 Year round applications  PhD Research Project  Self-Funded PhD Students Only