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PhD Projects, Programmes & Scholarships

We have 3,188 PhD Projects, Programmes & Scholarships

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Exhaled microbes and their detection by facemask sampling

  Research Group: Microbiology and Infection
We all breathe out numerous microbes, even when we are sleeping. Our group knows this through our work on facemask sampling (FMS). . Read more
 Supervisors: Prof M Barer, Dr N Garton
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Genome dynamics of tandem repeat expansions in lung disease

  Research Group: Genetics
Project Summary. Idiopathic Pulmonary Fibrosis (IPF) is a progressive and fatal lung disease affecting approximately 50 per 100,000 individuals in the UK. Read more
 Supervisors: Prof E Hollox, Dr R Badge
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Computational Neural Networks (CNNs), foundational large language models (LLMs), and pretrained transformers (GPTs) for phylogeny, biodiversity and functional genomics

  Research Group: Genetics
Artificial intelligence will transform the identification, measurement, conservation and exploitation of biodiversity and the understanding and applications that can come from genomics, transcriptomics and genome assemblies. Read more
 Supervisor: Dr PHH Heslop-Harrison
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The long and the short of human non-crossover recombination

  Research Group: Genetics
Meiotic recombination plays a central role in generating DNA diversity, which in turn provides the capacity for a species to evolve. Read more
 Supervisors: Dr C A May, Dr J Higgins
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Utilising Patient-Derived Explants to Elucidate Mechanisms of Resistance to PD-1/PD-L1 Inhibitors

  Research Group: Cancer Sciences
Project Summary. Immune checkpoint inhibitors targeting PD-1 and PD-L1 have transformed the therapeutic landscape for several solid cancers. Read more
 Supervisors: Dr G Miles, Dr GV Viticchie
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Assessing the tumour microenvironment and treatment response in endometrial cancer patient derived explants

  Research Group: Cancer Sciences
Project. Endometrial cancer is the most common gynaecological malignancy in many countries and although it is typically associated with a good long-term outcome the prognosis of metastatic endometrial cancer (EC) is very poor. Read more
 Supervisors: Dr E Moss, Dr G Miles
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Deciphering Pan-Cancer Tumour Microenvironment Ecosystems Using Single-Cell Atlases and Patient-Derived Explant Models

  Research Group: Cancer Sciences
Background/project proposal. Cancer is characterized by multi-cellular communities with complex interactions that shape disease progression, treatment responses, and patient survival [1]. Read more
 Supervisors: Dr G Miles, Dr GV Viticchie , Dr CD Demetriou
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Liquid biopsy for early detection and disease monitoring of aggressive T-cell lymphomas

  Research Group: Cancer Sciences
Background. T-cell lymphomas are rare but highly aggressive blood cancers. Despite advances in cancer research, outcomes for patients with these diseases have seen little improvement in the past 30 years. Read more
 Supervisors: Dr MA Ahearne, Dr H Walter
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Theory and Design of Complex Nanostructures for the Control of Light Scattering and Absorption

Electromagnetic scattering is the fundamental mechanism by which light allows us to perceive the world. At the same time, scattering from particles sets a fundamental limit on our ability to transmit and receive information using optical beams. Read more
 Supervisor: Dr F Papoff
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Laser Frequency Comb Technology for the Extremely Large Telescope

We are seeking to appoint a talented PhD candidate to join the Ultrafast Optics Group at Heriot-Watt by 1 October 2026 and help us to build cutting-edge laser technology for the world’s largest telescope—the ELT—creating ultra-precise “astrocomb” lasers that will enable some of the most exciting science in modern optical astronomy. Read more
 Supervisor: Prof D Reid
 Year round applications  PhD Research Project  Funded PhD Project (UK Students Only)
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Advanced Dual-Comb LiDAR: Precision 3D Metrology for Advanced Sustainable Manufacturing

We are seeking to appoint a talented PhD candidate to join the Ultrafast Optics Group at Heriot-Watt, to start by 1 October 2026, to develop a faster and more sensitive implementation of dual-comb ranging—an optical metrology technique combining interferometry-like precision with time-of-flight accuracy. Read more
 Supervisor: Prof D Reid
 Year round applications  PhD Research Project  Funded PhD Project (UK Students Only)
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Sex Determination and the Extinction Vortex

  Research Group: Genetics
This PhD will investigate whether the risk of extinction in Hymenoptera is greater than most other insect species because of a synergistic interaction between extrinsically driven decline and an intrinsic factor, their mechanism of sex determination. Read more
 Supervisor: Dr R Hammond
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Crystal growth and neutron scattering of functional materials

PhD Opportunity. Crystal growth and neutron scattering of functional materials. (UCL Crystal Growth Laboratory @ Rutherford Appleton Laboratory, Harwell Campus). Read more
 Supervisor: Prof R Perry
 Year round applications  PhD Research Project  Awaiting Funding Decision/Possible External Funding
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Toxicity and Ecotoxicity Assessment of Batteries

Are you a big picture thinker, concerned about sustainability and impacts on both human health and the environment? Would you like to explore how to make… Read more
 Supervisor: Dr J E Edge
 Year round applications  PhD Research Project  Funded PhD Project (European/UK Students Only)
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Predicting Early Development in Moderate to Late Preterm Babies

Over 80% of preterm babies are born between 32 and 36 weeks gestation. Read more
 Supervisor: Prof J Harding
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Using extracellular vesicles to develop a management decision aid for Acute Respiratory Distress Syndrome and Pulmonary Fibrosis

We are seeking talented, motivated students with a passion for research in Acute Respiratory Distress Syndrome to join Dr Rahul Mahida’s team in the Institute of Inflammation and Ageing at the University of Birmingham (https://www.birmingham.ac.uk/staff/profiles/inflammation-ageing/mahida-rahul.aspx). Read more
 Supervisor: Dr R Mahida
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Development of novel therapeutic strategies to target Mycobacterium tuberculosis virulence

Project Description. Mycobacterium tuberculosis (Mtb) is a sophisticated pathogen which can replicate in eukaryotic cells and survive in infected humans for decades. Read more
 Supervisor: Prof G Mukamolova
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Unmasking molecular pathways of sarcopenia and muscle dysfunction and their biomarkers

Sarcopenia is a disease that affects individuals both as part of the normal ageing process and as a consequence of systemic disease. Read more
 Supervisors: Dr H McAuley, Dr LAB Baker, Prof D Jones
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Inference and Error Detection in Reading: Cognitive and Linguistic Mechanisms

Can you spot the grammatical error this in sentence? Many readers initially fail to detect small disruptions in a sentence, such as an omitted word, an unintended repetition, or a swap of adjacent words. Read more
 Supervisors: Dr K Warrington, Dr V McGowan
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Improving meta-analysis of complex healthcare interventions: Application to chronic obstructive pulmonary disease

Health and social care interventions—like those for quitting smoking or managing weight—are often made up of several parts. For example, a smoking cessation programme might include motivational sessions, behaviour-change strategies, and different delivery formats (online, in-person, group sessions) [1]. Read more
 Supervisors: Dr S Freeman, Prof A Sutton, Dr ES Smith
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Exploring Oxygenase Chemistry: Enzymatic Pathways to Novel Antibiotics

Nature uses a remarkable range of oxygenase enzymes to perform highly selective oxidation reactions—transformations that are often challenging or wasteful to achieve chemically. Read more
 Supervisors: Dr H Kwon, Prof A Hudson
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Visualizing cellular control centres: Advanced imaging of centrosomes to understand disease

Project. Cells rely on tiny but essential structures called centrosomes, which act as control centres to organize their internal skeleton and guide cell division. Read more
 Supervisors: Dr R Mahen, Dr R Hirst
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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How do transcriptional kinases regulate cell cycle progression?

Project. Cyclin-dependent kinases (CDKs) are protein kinases performing essential functions by regulating cell cycle and RNA polymerase II transcription of protein-coding and non-coding genes. Read more
 Supervisors: Dr MT Tellier, Dr R Mahen
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the role of galectins in oncogenic KRAS signalling

Background. The RAS family of small GTPases serves as signalling hubs that regulate cell proliferation and differentiation. Notably, approximately 18% of all human cancers contain mutations in KRAS, one of the RAS isoforms (Catalogue Of Somatic Mutations In Cancer (COSMIC)). Read more
 Supervisors: Dr K Tanaka , Prof BG Gooptu
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Molecular characterization of suicidal phage-resistance mechanisms in bacteria

Importance. The proliferation of antibiotic resistance (AMR) through horizontal-gene-transfer (HGT) is a formidable health challenge, accounting for 700,000 deaths annually1. Read more
 Supervisors: Dr A Koyamangalath Vadakkepat , Dr M Clokie
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Multimodal Assessment of Falls Risk/ Movement Performance in Older Adults Using Wearable Sensor Technologies and Visual Computing Techniques

Falls are a leading cause of severe injury and loss of functional independence among older adults. Performance measures derived from gait and postural assessments offer valuable insight into an individual’s movement quality (and hence their falls risk). Read more
 Supervisors: Dr J Buckley, Prof R Qahwaji, Dr R Jaber
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Why do we get sick when we are stressed?

Hypothesis. We hypothesise that host stress, via catecholamine stress hormones (norepinephrine, epinephrine, dopamine), plays a critical role in triggering the transition of Streptococcus pneumoniae from a benign coloniser in the nasopharynx to an invasive pathogen. Read more
 Supervisors: Dr H Yesilkaya, Dr L Cuthbertson
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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AI-based dementia screening using emotion change detection in speech signals

With the development of AI tools, including machine/deep learning, speech signal processing has reached a high level of accuracy, both for neutral and expressive speech. Read more
 Supervisors: Dr Z Mnasri, Prof S Konur
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Structural insights into how Mycobacterium tuberculosis interacts with human cells

Project. Mycobacterium tuberculosis is the leading global cause of death from a single infectious agent. It is a highly specialised human pathogen and is able to adapt to changing conditions in human macrophages and granulomas in order to subvert immune defences. Read more
 Supervisors: Dr H O'Hare, Dr AKV Koyamangalath Vadakkepat
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Bacteria, Phages, and Iron: Decoding the Molecular Tug-of-War in Microbial Ecosystems

Iron is an essential nutrient for virtually all life on Earth, playing a critical role in processes such as respiration, DNA synthesis, and metabolism (1). Read more
 Supervisors: Dr C Jenul, Dr A Millard
 Year round applications  PhD Research Project  Self-Funded PhD Students Only