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We have 3,651 PhD Projects, Programmes & Scholarships

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PhD Projects, Programmes & Scholarships

We have 3,651 PhD Projects, Programmes & Scholarships

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Uncovering shared genetic and molecular mechanisms in multiple long-term conditions through multi-trait and multiomics approaches

  Research Group: Public Health & Epidemiology
This project is an example of the type of approaches that can be applied to a wide range of multiple long-term conditions. Thyroid disorders are common, affecting an estimated 1 in 20 people in the UK (British Thyroid Foundation, 2025). Read more
 Supervisors: Dr JC Chen, Prof F Dudbridge
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Impacts of environmental exposures on critically ill children: a national cohort study

  Research Group: Public Health & Epidemiology
Project background. Environmental exposures including air pollution, noise, greenspace and extreme temperature has each been investigated in relation to childhood health outcomes around the world[1]. Read more
 Supervisors: Dr SC Cai, Dr S Seaton, Prof A Hansell
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Eliciting Patient, Carer and Clinician Preferences for Virtual Ward Models in acute Atrial Fibrillation Care

  Research Group: Cardiovascular Sciences
Atrial fibrillation (AF) is one of the most common cardiac arrhythmias and associated with increased risk of stroke, hospitalisation, and reduced quality of life [1], [2], [3]. Read more
 Supervisor: Prof GY Yao
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The effect of glucagon-like peptide-1 receptor agonists on exercise adaptation

  Research Group: Cardiovascular Sciences
markers of adaptation. In parallel, the student will utilise muscle biopsies collected within the ongoing OPAL trial. Participants serve as their own control, with samples obtained at. Read more
 Supervisor: Dr EW Watson
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The genetics of disease progression; Are we using the right definition?

  Research Group: Cardiovascular Sciences
Genetic studies of disease primarily look at risk by comparing cases (with the disease) to controls. There is now great interest in investigating the potential role of genomic data on progression and prognosis for those living with disease. Read more
 Supervisors: Dr CN Nelson, Prof F Dudbridge
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Identifying novel genes and pathways regulating human telomere length

  Research Group: Cardiovascular Sciences
Telomeres are protein bound stretches of repetitive DNA at the end of linear chromosomes that prevent the end of the DNA being incorrectly recognised as a DNA break. Read more
 Supervisors: Dr V Codd, Dr CN Nelson
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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From metabolism to immunity: rediscovering SGLT2

  Research Group: Cardiovascular Sciences
SGLT2 inhibitors are widely prescribed for type 2 diabetes, yet their true potential may extend far beyond blood sugar control. Clinical trials have already shown that these drugs reduce cardiovascular events, protect the kidney, and improve survival. Read more
 Supervisor: Dr EA Akalestou
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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SGLT2 inhibitors and mitochondrial function: a new avenue for an existing drug

  Research Group: Cardiovascular Sciences
Sodium–glucose cotransporter 2 (SGLT2) inhibitors are an established class of antidiabetic drugs that have demonstrated additional benefits beyond glycaemic control, including cardiovascular and renal protection. Read more
 Supervisors: Dr EA Akalestou, Dr LAB Baker
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the roles that G protein coupled receptors play in hypertension

  Research Group: Molecular & Cell Biology
G protein-coupled receptors (GPCRs) constitute a very large family of heptahelical, integral membrane proteins that mediate a wide variety of physiological processes ranging from the transmission of light and odorant signals to the mediation of neurotransmission and hormonal actions. Read more
 Supervisor: Dr J Willets
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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PhD Studentship in Sustainable Grease Lubrication

Applications are invited for a research studentship in the field of Sustainable Grease Lubricant, leading to the award of a PhD degree. The post is supported by a bursary and fees (at the UK student rate) provided by  EPSRC/Shell IDLA award. Read more
 Supervisor: Dr J Wong
 Year round applications  PhD Research Project  Funded PhD Project (UK Students Only)
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PhD Studentship in Water-Based Lubrication

Applications are invited for a research studentship in the field of Tribology and Lubrication, leading to the award of a PhD degree. The post is supported by a bursary and fees (at the UK student rate) provided by the EPSRC/Shell IDLA award. Read more
 Supervisor: Dr J Wong
 Year round applications  PhD Research Project  Funded PhD Project (UK Students Only)
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Reactive Sulfur Species: Unlocking Nature’s Hidden Chemistry for Health and Sustainability

  Research Group: Molecular & Cell Biology
Have you ever wondered what really drives life under stress? For decades, biology has focused on reactive oxygen species (ROS) as the main players in health and disease. Read more
 Supervisor: Dr CS Switzer
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Epigenetics of early human embryonic development

  Research Group: Molecular & Cell Biology
The 46th chromosome in XX female mammals, the second X, has to be switched off. That way females equalize gene dosage of X-linked genes with XY males. Read more
 Supervisors: Dr Y Markaki, Dr MT Tellier
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Long non-coding RNAs and its biological functions

  Research Group: Molecular & Cell Biology
In addition to ~20,000 protein coding genes, human genome contains ~30,000 genes that encode for functional RNAs. Apart from the rRNAs and tRNAs that are involved in translation, the famous example is the Xist RNA involved in silencing of one X chromosome in females. Read more
 Supervisors: Dr O V Makarova, Dr Y Markaki, Dr MT Tellier
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Decoding CDR Dynamics to Engineer High Affinity Antibodies for Next Generation Therapeutics

  Research Group: Molecular & Cell Biology
Project Summary. This project will investigate how complementarity‑determining region (CDR) structural dynamics guide affinity maturation in antibodies, with the goal of improving their use in global health and biotechnology. Read more
 Supervisors: Dr G Hall, Dr F Muskett
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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From Genes to Signals: Visualising Molecular Interactions in Bacterial Communities

  Research Group: Microbiology and Infection
Microbial communities are shaped by dynamic interspecies interactions that influence gene expression, metabolite production, and ecological behaviour. Read more
 Supervisors: Dr K Schilcher, Dr Y Markaki
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Bacteriophages to treat bacterial infections

  Research Group: Microbiology and Infection
Bacteriophages are viruses that infect bacteria, playing vital roles in shaping microbial communities and influencing health and disease. Read more
 Supervisor: Dr SM A Millard, E Galyov, M Clokie
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Digital Engineering

Digital engineering underpins our research in all our thematic areas and is also an area where we lead in the development of the underpinning methodologies. Read more
 Supervisor: Dr S Kenny
 31 July 2026  PhD Research Project  Self-Funded PhD Students Only
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Bioengineering and Healthcare Technologies

Sustainable production of next-generation pharmaceuticals and biologics to meet future healthcare needs is a key area of research at Loughborough. Read more
 Supervisor: Dr DJ Malik
 31 July 2026  PhD Research Project  Self-Funded PhD Students Only
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Exploring the Respiratory mycobiome in Tuberculosis

  Research Group: Microbiology and Infection
The latest WHO reports that around 10.7 million people were diagnosed and 1.23 million people died from the curable and preventable disease tuberculosis (TB) in 2024, putting it in the top 10 causes of death worldwide1. Read more
 Supervisors: Dr LC Cuthbertson, Prof G Mukamolova
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Hydrogen, Clean and Sustainable Energy

Generating clean and sustainable energy is a key global challenge and a real strength of the school, with work spanning fundamental research into novel materials and technologies all the way through to the scale up of these techniques towards industry readiness. Read more
 Supervisor: Dr J Wagner
 31 July 2026  PhD Research Project  Self-Funded PhD Students Only
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Exhaled microbes and their detection by facemask sampling

  Research Group: Microbiology and Infection
We all breathe out numerous microbes, even when we are sleeping. Our group knows this through our work on facemask sampling (FMS). . Read more
 Supervisors: Prof M Barer, Dr N Garton
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Sustainable and Smart Materials

Materials lie at the heart of many of the world’s global challenges from how we generate our future energy, through the sustainable use of resources and the reduction of use of rare materials to designing for recycling. Read more
 Supervisor: Dr S Hogg
 31 July 2026  PhD Research Project  Self-Funded PhD Students Only
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Genome dynamics of tandem repeat expansions in lung disease

  Research Group: Genetics
Project Summary. Idiopathic Pulmonary Fibrosis (IPF) is a progressive and fatal lung disease affecting approximately 50 per 100,000 individuals in the UK. Read more
 Supervisors: Prof E Hollox, Dr R Badge
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Computational Neural Networks (CNNs), foundational large language models (LLMs), and pretrained transformers (GPTs) for phylogeny, biodiversity and functional genomics

  Research Group: Genetics
Artificial intelligence will transform the identification, measurement, conservation and exploitation of biodiversity and the understanding and applications that can come from genomics, transcriptomics and genome assemblies. Read more
 Supervisor: Dr PHH Heslop-Harrison
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The long and the short of human non-crossover recombination

  Research Group: Genetics
Meiotic recombination plays a central role in generating DNA diversity, which in turn provides the capacity for a species to evolve. Read more
 Supervisors: Dr C A May, Dr J Higgins
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Utilising Patient-Derived Explants to Elucidate Mechanisms of Resistance to PD-1/PD-L1 Inhibitors

  Research Group: Cancer Sciences
Project Summary. Immune checkpoint inhibitors targeting PD-1 and PD-L1 have transformed the therapeutic landscape for several solid cancers. Read more
 Supervisors: Dr G Miles, Dr GV Viticchie
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Assessing the tumour microenvironment and treatment response in endometrial cancer patient derived explants

  Research Group: Cancer Sciences
Project. Endometrial cancer is the most common gynaecological malignancy in many countries and although it is typically associated with a good long-term outcome the prognosis of metastatic endometrial cancer (EC) is very poor. Read more
 Supervisors: Dr E Moss, Dr G Miles
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Deciphering Pan-Cancer Tumour Microenvironment Ecosystems Using Single-Cell Atlases and Patient-Derived Explant Models

  Research Group: Cancer Sciences
Background/project proposal. Cancer is characterized by multi-cellular communities with complex interactions that shape disease progression, treatment responses, and patient survival [1]. Read more
 Supervisors: Dr G Miles, Dr GV Viticchie , Dr CD Demetriou
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Liquid biopsy for early detection and disease monitoring of aggressive T-cell lymphomas

  Research Group: Cancer Sciences
Background. T-cell lymphomas are rare but highly aggressive blood cancers. Despite advances in cancer research, outcomes for patients with these diseases have seen little improvement in the past 30 years. Read more
 Supervisors: Dr MA Ahearne, Dr H Walter
 Year round applications  PhD Research Project  Self-Funded PhD Students Only

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