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PhD Projects, Programmes & Scholarships

We have 3,177 PhD Projects, Programmes & Scholarships

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Intranasal delivery of nucleic acid therapeutics for neurodegenerative diseases using a novel peptide carrier

Neurodegenerative diseases such as Alzheimer’s and Parkinson’s Disease represent a growing global health burden, with limited treatment options that effectively target the brain. Read more
 Supervisors: Dr E McErlean, Dr V Kett
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Integrating Organ-on-a-Chip Systems into Preclinical Drug Screening Pipelines

The development and testing of drugs currently rely mainly on animal models, which may require many years before results can be translated into clinical practice. Read more
 Supervisor: Prof D Lamprou
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Innovative 3D-Printed Food-Based Systems for Immune Enhancement

Recent advances in nutritional science and technological innovation have led to pioneering methods for delivering essential nutrients that the body cannot produce in sufficient amounts, such as vitamins, minerals, and amino acids. Read more
 Supervisor: Prof D Lamprou
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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In-cell quantification of drug concentrations by using advanced nano-sensor

In-cell quantification of drug concentrations is fundamentally important to drug function, efficacy and toxicity, and for understanding and accurately predicting drug interactions and inter-subject variability in drug response (either on-target or off-target effects). Read more
 Supervisor: Dr YG Ge
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Development and evaluation of a lung-on-a chip device for screening novel antimicrobials

On-going studies by our group have revealed a complex and diverse microbiota in the airways of Cystic fibrosis (CF) patients, which affects disease progression. Read more
 Supervisor: Prof M Tunney
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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3D printing of drug delivery implants

Additive manufacturing (AM) encompasses a wide range of processes that create structures through deposition or binding of materials in successive layers to produce a 3D object. Read more
 Supervisor: Dr P Boyd
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Chip-Scale Atomic Devices

Over the past decade, quantum sensors have rapidly progressed and have demonstrated their exceptional stability and precision. They have gathered significant interest from fundamental research and real-world applications, including navigation. Read more
 Supervisor: Dr YH Lien
 Year round applications  PhD Research Project  Funded PhD Project (UK Students Only)
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Untangling how Metal Dyshomeostasis Pathologically Interacts with Protein Aggregates to Drive Neurodegeneration

Lewy Body Dementia (LBD) consists of two syndromes, Dementia with Lewy Bodies (DLB) and Parkinson’s Disease with Dementia (PDD). Cognitive and motor symptom order differs, but phenotypes eventually converge. Read more
 Supervisor: Dr I Pienaar
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Creating Clinically Relevant Novel 3-Dimensional Neuronal-Glial Cell Models for Understanding the Molecular Pathology of Multiple System Atrophy’s Neurodegeneration

Multiple System Atrophy (MSA) is a rare, progressive neurological disorder that is without cure, that causes nerve cell loss in the brain, leading to issues with movement, balance, blood pressure, bladder control, and digestion, as the autonomic system is also affected. Read more
 Supervisor: Dr I Pienaar
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Connections Between the Nucleus, the Cytoskeleton and Tumorigenesis

We are seeking highly motivated PhD students to investigate how interactions between the nucleus and the cytoskeleton contribute to tumorigenesis and cancer cell migration. Read more
 Supervisor: Prof G Gerlitz
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Sonars for precise underwater autonomous vehicle (AUV) navigation.

  Research Group: Communication Technologies
There is a great interest in underwater autonomous vehicles (AUVs) and currently many companies develop AUVs for multiple applications. Read more
 Supervisor: Dr Y Zakharov
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Full-duplex underwater acoustic systems

  Research Group: Communication Technologies
Acoustic signal transmission is the only feasible technology for long-range (>10-100m) underwater communication, navigation and sonar systems. Read more
 Supervisor: Dr Y Zakharov
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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High-frequency underwater acoustic communication for image transmission.

  Research Group: Communication Technologies
Communication using acoustic waves is the main underwater communication technology, since electro-magnetic waves quickly attenuate underwater. Read more
 Supervisor: Dr Y Zakharov
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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High data rate adaptive underwater acoustic networks

  Research Group: Communication Technologies
The ocean plays a key role in supporting all living organisms on our planet, yet the vast majority of the ocean remains unmapped and unobserved. Read more
 Supervisor: Dr Y Zakharov
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Machine learning in underwater acoustic communication modems

  Research Group: Communication Technologies
Machine learning is an approach that is useful when a practical optimisation problem is difficult to describe precisely. This approach has found multiple applications. Read more
 Supervisor: Dr Y Zakharov
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Smart supramolecular assembly for pathology-responsive and long-acting drug delivery applications

This PhD will design and develop ionic liquid–enabled supramolecular formulations capable of in situ sol-to-gel transition triggered by pathological microenvironmental cues such as acidic pH, reactive oxygen species (ROS), and enzyme activity. Read more
 Supervisors: Dr LV Vora, Prof R Thakur
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Smart, responsive biomaterials for infection-resistant medical devices

A major problem associated with medical devices is infection. With infection rates of approaching 100% in some devices, ways to prevent formation of bacterial biofilm on medical device surfaces are urgently required. Read more
 Supervisors: Prof C McCoy, Dr M Wylie
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Structure-based design of allosteric modulators for G protein-coupled receptors using molecular modelling and pharmacology experiments

Almost all physiological processes are regulated through the activation of G protein-coupled receptors (GPCRs). It has become widely accepted that most GPCRs possess binding sites spatially distinct from their natural ligand binding site (orthosteric site), termed as allosteric sites. Read more
 Supervisor: Dr I Tikhonova
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Sustained Release of Eutectic systems composed of Local Anaesthetics and non-steroidal anti-inflammatory agents from biodegradable electrospun mats to Enhance Post-Surgical Recovery

Major abdominal surgery is a metabolically and psychologically significant event associated with prolonged recovery and convalescence. Read more
 Supervisor: Prof D Jones
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Transforming Drug Delivery: AI and Machine Learning in Design, Optimization, and Personalization

This research explores the transformative role of digital technologies, particularly machine learning, microfluidics, and bioprinting, in advancing pharmaceutical design and therapeutic delivery. Read more
 Supervisor: Prof D Lamprou
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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VAPShield: Development of next-generation endotracheal tube materials for the prevention of ventilator-associated pneumonia

Critically ill patients often depend on life-saving devices such as breathing tubes, called endotracheal. tubes (ETTs), to help them breathe when they cannot do so on their own. Read more
 Supervisors: Dr M Wylie, Prof C McCoy
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Next-Generation High-level Disinfectants: Targeting Bacterial Persistence on Medical Surfaces

This PhD project explores the development and mechanistic evaluation of advanced disinfection technologies targeting bacterial spores and biofilm-forming pathogens on hard surfaces and medical devices. Read more
 Supervisors: Dr M Wylie, Prof C McCoy
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Next-Gen Drug Delivery: Microfluidic Encapsulation of Biologics into Smart Nanocarriers

Provide a brief description of the project. Progress in drug design has led to the development of new peptides, proteins, and drug molecules. Read more
 Supervisor: Prof D Lamprou
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Multipurpose gel formulations containing antiretroviral-loaded lactoferrin nanoparticles and antibiotics for combination HIV prevention and treatment of bacterial vaginosis

Summary descriptive text / Example of research project  . Lactoferrin . Lactoferrin is a multifunctional globular protein. Read more
 Supervisors: Dr S Carmali, Prof K Malcolm
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Microfluidic Encapsulation of biologics into Nanomedicines

Progress in drug design has led to the development of new peptides, proteins, and drug molecules. However, the limited ability to deliver selectively these molecules at well-defined dosing regimens and without invoking drug-resistance remains a significant challenge. Read more
 Supervisor: Prof D Lamprou
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Medicines optimisation in palliative and end of life care

  Research Group: Healthcare delivery and medicines optimisation
Medicines optimisation at the end of life is essential in palliative and end of life care, where the priority shifts from disease treatment to enhancing quality of life and minimising harm. Read more
 Supervisor: Dr C Parsons
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating Non-thermal ‘Cold’ Plasmas for Enhancing the Delivery and Efficacy of Antibiotics and Complex molecules to biofilms of clinically relevant bacteria

  Research Group: Infection and antimicrobial resistance
Biofilms, complex multi-species consortia of microorganisms existing either as surface attached communities or non-surface-attached aggregates, are characterised by significantly elevated tolerance to antimicrobial challenges and often an inability to adequately treat the infection with conventional antibiotics. Read more
 Supervisors: Prof B Gilmore, Dr T Thompson
 Year round applications  PhD Research Project  Funded PhD Project (UK Students Only)
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Infection-responsive coatings for the prevention of catheter-associated urinary tract infections

Medical care has transformed over the last century with significant improvements in the variety and extent to which various diseases can be treated and/or prevented. Read more
 Supervisor: Dr M Wylie
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Formulation of hybrid peptide-lipid nanoparticle formulations for targeted nucleic acid delivery

The project aims to develop next-generation delivery systems that combine the structural advantages of lipid nanoparticles with the targeting and membrane-translocating properties of peptides. Read more
 Supervisors: Dr E McErlean, Dr V Kett
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Elucidating novel anti-cancer drug responses in advanced ovarian cancer

Ovarian cancer is one of the most lethal gynaecological malignancies, often diagnosed at advanced stages due to non-specific symptoms and a lack of early detection methods. Read more
 Supervisor: Dr F Furlong
 Year round applications  PhD Research Project  Self-Funded PhD Students Only