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PhD Projects, Programmes & Scholarships

We have 3,359 PhD Projects, Programmes & Scholarships

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Evaluating the genetic basis and evolution of virulence and antimicrobial drug resistance in Helicobacter pylori in a populational model

University of Leicester
Department of Genetics, Genomics and Cancer Sciences
Project background. Characterization of the genetic variation of bacterial species and the evolutionary mechanisms leading to that variation is crucial for understanding bacterial adaptation to their host environments, as well as the evolution of phenotypes such as virulence and antimicrobial drug resistance (AMR). Read more
 Supervisors: Dr S Beleza, Dr K Schilcher, Dr FF Freund
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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AI for Understanding and Safeguarding Online Social Networks: Mapping Dynamics and Countering Threats

University of Bradford
Faculty of Engineering & Digital Technologies
Online social networks have become central to how people share news, form opinions, and connect with communities, shaping both social behaviour and public perception on a global scale. Read more
 Supervisors: Dr A Zareie, Prof S Konur
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Non-tuberculous mycobacteria in agrifood and the environment at the human-animal-ecosystems interface: resistance, persistence and longevity

University of Leicester
Department of Respiratory Sciences
Second Supervisor. Dr Marie Kirby, Agriculture and Environment, Harper Adams University. Project Outline. Environmentally resident mycobacteria are important animal pathogens known to infect cattle, pigs, fowl, sheep and most other commercially valuable livestock. Read more
 Supervisor: Dr J Pearl
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Development of a Patient-Specific Corneal Digital Twin Based on Topographic Imaging for Contact Lens Fitting and Future Corneal Interventions

University of Bradford
Faculty of Engineering & Digital Technologies
This PhD project aims to develop a patient-specific corneal digital twin derived exclusively from routinely acquired corneal topography and tomography data. Read more
 Supervisors: Prof R Qahwaji, Dr I Ghafir
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Exploring Weather Events Affecting The Health and Emergency intensive care admissions of children using Routine data: the WEATHER study

University of Leicester
Department of Population Health Sciences
Background. Climate change and air pollution pose a significant global challenge, disproportionately affecting the health and lives of children.1 Despite lifelong exposure, little is known about how weather impacts children, even though air pollution, which is closely linked with weather, harms every organ in the body. Read more
 Supervisors: Dr S.E. Seaton, Prof J Manning, Dr TL Lucas
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Design, synthesis and evaluation of novel polysialyltransferase inhibitors as anti- metastatic agents

University of Bradford
Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases (polySTs). Read more
 Supervisors: Prof R Falconer, Dr S Shnyder
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Design, synthesis and evaluation of protease-activated anti-cancer prodrugs

University of Bradford
Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more
 Supervisors: Prof R Falconer, Prof P Loadman
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Polysialyltransferases as a target in metastatic cancer

University of Bradford
Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases. Read more
 Supervisors: Prof R Falconer, Dr S Shnyder
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Mapping cardiac microstructure in aortic stenosis and diabetes using diffusion MRI and machine learning

University of Leicester
Cardiovascular Sciences
Heart failure remains one of the leading causes of hospitalisation and death worldwide. Two of its most important causes, type 2 diabetes and aortic stenosis, both lead to thickening and stiffening of the heart muscle, but the microscopic processes underlying these changes are not fully understood. Read more
 Supervisors: Dr M Afzali, Prof G McCann, Dr A Singh, Dr TP Pearce
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Aldehyde dehydrogenase expression and function in cancer stem cells

University of Bradford
Faculty of Life Sciences
Aldehyde dehydrogenases (ALDHs) catalyse the oxidation and detoxification of reactive endogenous and exogenous aldehydes into carboxylic acids via NAD+ coupled reduction. Read more
 Supervisors: Prof K Pors, Dr S Swaroop, Dr A Ruiz Estrada
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Development of chemical tools and bioactive compounds to explore the importance of enzyme activity in cancer diseases

University of Bradford
Faculty of Life Sciences
Diversity-oriented synthesis (DOS) is a modern chemical methodology, which aims to synthesise small molecules that cover new chemical space with the possibility of finding unexplored biological targets or pathways that may be important for disease progression. Read more
 Supervisors: Prof K Pors, Dr V Jha, Dr Muhammad Wahajuddin
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Our agricultural future: Crop genomics, biodiversity and phylogenetics in the context of evolution of genome organization, epigenetics, and phylogenetics

University of Leicester
Department of Genetics, Genomics and Cancer Sciences
At the forefront of agricultural genetics, the fundamental objectives of the project aim to define biodiversity and relationships of agricultural species and their wild relatives, leading to prospects for developing new genotypes and approaches to increase farm sustainability and ensure food security. Read more
 Supervisor: Prof P HESLOP-HARRISON
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Development of antibody-drug conjugates (ADCs) for oncology indications

University of Bradford
Faculty of Life Sciences
A major challenge in cancer therapy is to develop therapeutic agents that selectively target tumour cells but are not harmful to normal tissue. Read more
 Supervisors: Prof K Pors, Dr Muhammad Wahajuddin, Prof R Falconer
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Consequences of CD20 ligation in diffuse large B cell lymphoma

University of Leicester
Molecular and Cell Biology
The addition of the monospecific chimeric CD20 antibody rituximab to chemotherapy transformed outcomes for patients with DLBCL without additional significant toxicities (1). Read more
 Supervisors: Dr H Walter, Dr Y Markaki, Prof M J S Dyer
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating genetic and circadian rhythm effects on radiotherapy side effects for breast cancer

University of Leicester
Department of Genetics, Genomics and Cancer Sciences
Project. Radiotherapy is an effective form of cancer therapy that targets high energy irradiation to the tumour volume, resulting in destruction of cancer cells and improved survival. Read more
 Supervisors: Dr C J Talbot, Dr TR Rattay
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Environmentally induced DNA methylation – a passive biomarker or driver of genetic mutation?

University of Leicester
Department of Genetics, Genomics and Cancer Sciences
Project. DNA methylation is a core epigenetic mechanism involved in regulating gene expression, mediating environmental responses, and potentially influencing genome evolution. Read more
 Supervisor: Dr H Marshall
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Unlocking the Secrets of Ageing: Exploring Epigenetic Clocks in the Jewel Wasp Nasonia vitripennis

University of Leicester
Department of Genetics, Genomics and Cancer Sciences
Why do we age, and can that process be slowed? This project explores one of biology’s most fascinating and urgent questions by studying how tiny insects can reveal universal rules of ageing. Read more
 Supervisors: Prof E Mallon, Dr K Chen
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Identifying the neurogenetic network underlying visually-driven sleep

University of Leicester
Department of Genetics, Genomics and Cancer Sciences
Drosophila Sleep Neurogenetics Laboratory at University of Leicester is open to supervise enthusiastic students for their PhD research in the area related to neurogenetic mechanisms underlying visually-driven sleep. Read more
 Supervisors: Dr K Chen, Dr E Rosato, Dr R Feuda
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Exploration of novel molecular photoswitches

University of St Andrews
School of Chemistry
  Research Group: Kilian group
Research activities in Kilian group are centred on the design and synthesis of novel organophosphorus and heavier Group 15 (As, Sb, Bi) organoelement compounds. Read more
 Supervisor: Dr P Kilian
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Data-Driven Numerical Modelling of Materials for High-Temperature Nuclear and Energy Applications

University of Sheffield
School of Mechanical, Aerospace and Civil Engineering
Next-generation nuclear and fusion energy systems place unprecedented demands on structural and functional materials, which must operate reliably under extreme thermal, mechanical, and environmental conditions. Read more
 Supervisor: Dr G Torelli
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Numerical Simulation of Concrete Fracture under Extreme Conditions using Phase-Field Methods

University of Sheffield
School of Mechanical, Aerospace and Civil Engineering
Concrete structures in energy, industrial, and civil infrastructure are frequently exposed to demanding conditions, such as multiaxial mechanical stresses, fire-induced thermal loading, and/or harsh environmental exposure. Read more
 Supervisor: Dr G Torelli
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Data-Driven Numerical Modelling of Material Behaviour for Finite Element Simulation

University of Sheffield
School of Mechanical, Aerospace and Civil Engineering
Modern infrastructure increasingly relies on materials whose composition varies due to local resources, alternative binders, and sustainability-driven formulations. Read more
 Supervisor: Dr G Torelli
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Combatting multi-drug resistant bacteria

University of Birmingham
Department of Microbes, Infections and Microbiomes
Antimicrobial resistance (AMR) is a major crisis for human medicine. Globally, untreatable bacterial infections are increasing, leaving limited treatment options. Read more
 Supervisors: Dr M Buckner, Dr DW Cleary
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Ensuring Well-Being in the Age of Generative AI

Edinburgh Napier University
School of Computing, Engineering & the Built Environment
Generative AI is rapidly transforming diverse sectors, yet its implications for well-being remain underexplored. Beyond productivity gains, concerns are emerging around heightened performance expectations, reduced autonomy, and career uncertainty in AI-augmented environments. Read more
 Supervisors: Dr SR Rafi, Dr AU Ullah
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Agile Coaching activity within an Organisational Learning context

Edinburgh Napier University
School of Computing, Engineering & the Built Environment
There are currently many agile coaches and those tasked with mentoring remits within the IT function. Little is known about the involvement and role of agile coaches regards the adoption and deployment of agile methods (Stray et al, 2020) with inconsistent approaches and varying successes (Theobald et al, 2020). Read more
 Supervisor: Dr PC Chita
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Large Language Models for Vulnerability Detection

Edinburgh Napier University
School of Computing, Engineering & the Built Environment
As software systems grow in complexity, the need for automated methods to detect vulnerabilities such as buffer overflows, SQL injections, and cross-site scripting becomes increasingly critical. Read more
 Supervisors: Dr KB Babaagba, Dr MU Ullah
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Integrating DevOps practices into ML-driven systems: A Framework and Maturity Model for Continuous Machine Learning Development

Edinburgh Napier University
School of Computing, Engineering & the Built Environment
The rapid adoption of Machine Learning (ML) across industries has transformed how systems are built, deployed, and maintained. Read more
 Supervisors: Dr SR Rafi, Dr AU Ullah
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Defeating complex families of malware using evolutionary based adversarial learning

Edinburgh Napier University
School of Computing, Engineering & the Built Environment
Malicious software continues to evolve rapidly, posing significant risks to information systems and organisational networks. Read more
 Supervisor: Dr KB Babaagba
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Trust and Generative AI in Agile Software Development: Building the Next-Generation Trust Maturity Model

Edinburgh Napier University
School of Computing, Engineering & the Built Environment
Trust is the invisible glue that holds Agile software development together. Teams rely on openness, accountability, and shared confidence to deliver high-quality software at speed. Read more
 Supervisors: Dr OB Bamgboye, Dr BD Davison
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Addressing Edinburgh and South East Scotland's Construction Skills shortfall

Edinburgh Napier University
School of Computing, Engineering & the Built Environment
The proposed research will support the development and delivery of the Housing Construction and Infrastructure Skills Gateway. Read more
 Supervisor: Dr KL Leitch
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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