We have 60 University of Bristol PhD Projects, Programmes & Scholarships

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University of Bristol PhD Projects, Programmes & Scholarships

We have 60 University of Bristol PhD Projects, Programmes & Scholarships

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Funded project GW4 BioMed3 MRC DTP - Quantifying the impact of heatwaves on cognition, neuroanatomy, and mitochondrial function

Climate change is increasing the frequency, duration, and severity of heatwaves worldwide. In the UK, extreme heat events are becoming increasingly common and are projected to intensify over coming decades. Read more
 Supervisor: Dr H Siviter
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Funded project GW4 BioMed3 MRC DTP - Optimising uptake and personalisation of digital health interventions for under-served groups: a case study with the Drink Less app

Digital health interventions can be effective at changing behaviours and can overcome lots of barriers to receiving face-to-face interventions such as stigma and accessibility. Read more
 Supervisors: Dr C Garnett, Dr O Maynard, Assoc Prof AA Attwood
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Funded project GW4 BioMed3 MRC DTP - Quietly healing trauma: enhancing emotional processing during sleep with targeted memory reactivation

Over 80% of people experience a traumatic event during their lifetime; of these, up to ~10% develop post-traumatic stress disorder (PTSD). Read more
 Supervisors: Dr R Purple, Prof M Jones
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Funded project GW4 BioMed3 MRC DTP - Linking neuronal function to mental health: How genetic risk factors impair cognitive flexibility and neural plasticity in schizophrenia.

Genetic risk factors are highly significant in determining susceptibility to a range of psychiatric disorders including anxiety, depression and schizophrenia. Read more
 Supervisor: Prof J Mellor
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Funded project GW4 BioMed3 MRC DTP - Using human genomics, AI and fly disease modelling to study the relationship between sleep and Alzheimer’s disease

Background. Our 24-hour body clock or circadian rhythms controls sleep-wake cycles timing. We helped show rhythms become weaker and sleep fragmented in old age (https://circadiageing.org.uk). Read more
 Supervisor: Prof J Hodge
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Funded project GW4 BioMed3 MRC DTP - Developing brain-activity based non-invasive stimulation techniques for movement disorders

Parkinson’s disease and dystonia are neurological disorders that cause disabling movement impairments. The effectiveness of current treatments varies substantially between individuals, and approximately 20–35% of people with dystonia are dissatisfied with their treatment. Read more
 Supervisors: Dr P Fischer, Prof M Jones
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Funded project GW4 BioMed3 MRC DTP - What drives the pain? Exploring the peripheral component in models of central sensitisation.

Chronic primary pain is pain for more than three months without an identified underlying injury or disease that explains its severity. Read more
 Supervisor: Dr J Dunham
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Funded project GW4 BioMed3 MRC DTP - Molecular basis of CASK mutations and their role in neural development

CASK is a highly conserved, multi-domain scaffolding protein that plays essential roles in synaptic development, neuronal communication, and brain formation. Read more
 Supervisors: Dr RC Corey, Prof J Hodge, Dr A Knapp-Wilson
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Funded project GW4 BioMed3 MRC DTP - Timing is Everything: Aligning Mealtime and Drug Treatment with the Body Clock to Fight Obesity

Life on Earth is subordinate to periodic alterations in the environment, with most notable changes seen from day to night. To adapt to these cyclic changes, living organisms evolved endogenous 24h timekeeping mechanisms named circadian clocks. Read more
 Supervisors: Dr LC Chrobok, Prof HP Piggins
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Funded project GW4 BioMed3 MRC DTP - Cerebellar orchestration of social behaviour

Background. The importance of the cerebellum to regulate social behaviours is increasingly becoming apparent. Read more
 Supervisors: Dr E Cahill, Dr P Anastasiades, Dr P Chadderton
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Funded project GW4 BioMed3 MRC DTP - Uncovering interneuron dysfunction in a mouse model of schizophrenia

Schizophrenia is a highly debilitating neurodevelopmental disorder impacting about 1% of the global population. While it is well established that schizophrenia is associated with altered function in key brain areas, such as the hippocampus, the precise cellular mechanisms are unknown. Read more
 Supervisor: Dr P Anastasiades
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Funded project GW4 BioMed3 MRC DTP - Investigating mechanisms of cell competition in breast cancer susceptibility and early tumour initiation

IMPORTANCE. Interactions between cancer cells and their non-cancerous counterparts play pivotal roles in modulating tumour growth. Read more
 Supervisors: Dr B Lloyd-Lewis, Dr E Piddini, Dr R Richmond
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Funded project GW4 BioMed3 MRC DTP - Alternative fates of PINK1 and its role in mitochondrial quality control, energy production and Parkinson’s Disease

BACKGROUND. Mitochondria are organelles of eukaryotic cells critical for energy production (ATP), metabolic regulation and biosynthesis. Read more
 Supervisors: Prof I Collinson, Dr RC Corey
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Funded project GW4 BioMed3 MRC DTP - Overcoming β-lactamase-mediated antibiotic resistance by combining biomolecular simulation and experiment

Rising antibiotic resistance is a major problem for human health. Resistance to β-lactams, the single most important antibiotic class, usually arises through their breakdown by β-lactamases (BLs). Read more
 Supervisors: Dr M van der Kamp, Dr J Spencer
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Funded project GW4 BioMed3 MRC DTP - Understanding beta-lactam antibiotic targets to improve melioidosis treatment

Melioidosis, caused by the soil-borne Gram-negative bacterium Burkholderia pseudomallei, is an under-recognised tropical disease, with mortality rates that can exceed 40 % for respiratory infections, that causes c. Read more
 Supervisors: Dr J Spencer, Prof A J Mulholland
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)