We have 7 Institute of Cancer Research PhD Projects, Programmes & Scholarships

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Institute of Cancer Research PhD Projects, Programmes & Scholarships

We have 7 Institute of Cancer Research PhD Projects, Programmes & Scholarships

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Evaluating the function of podoplanin (PDPN)+ cancer-associated fibroblasts (CAFs) in bladder cancer biology

Bladder cancers which are enriched for cancer-associated fibroblasts (CAF) have poor therapeutic outcomes. We have identified that a CAF population that stains positively for podoplanin (PDPN) is the most common CAF subtype. Read more
 Supervisor: Dr A Wilkins
 16 November 2026  PhD Research Project  Funded PhD Project (Students Worldwide)
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Identifying novel strategies to directly target IRF4 – the Achilles heel of myeloma

Interferon regulatory factor 4 (IRF4) is the key driver of the aberrant transcriptional programme in the bone marrow malignancy myeloma, and described as its Achilles heel. Read more
 Supervisor: Dr C Pawlyn
 16 November 2026  PhD Research Project  Funded PhD Project (Students Worldwide)
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Tumour-intrinsic reprogramming of tissue-resident macrophages in liver metastasis

Metastasis, rather than the primary tumour, leads to the majority of cancer-related deaths, with the liver representing one of the most frequent sites of metastasis for solid tumours. Read more
 Supervisor: Dr D Kung-Chun Chiu
 16 November 2026  PhD Research Project  Funded PhD Project (Students Worldwide)
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How Neoadjuvant Chemotherapy Reshapes Therapeutic Niches in Soft Tissue Sarcomas

Soft tissue sarcomas (STS) are a rare and heterogeneous group of malignancies arising from connective tissues such as muscle, fat and nerve sheaths. Read more
 Supervisor: Prof P Huang
 16 November 2026  PhD Research Project  Funded PhD Project (Students Worldwide)
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Enhancing systemic oncolytic virus delivery and efficacy in Paediatric-type diffuse high-grade gliomas using nanoparticle virus encapsulation and focused ultrasound

Paediatric-type diffuse high-grade gliomas (PDHGG) are aggressive childhood brain tumours with devastating prognosis (1). Immunotherapy for these patients is gathering momentum (2). Read more
 Supervisor: Dr E Harris
 16 November 2026  PhD Research Project  Funded PhD Project (Students Worldwide)
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Understanding how ARID1A shapes chromatin structure, composition, and function

ARID1A is a defining subunit of the BAF chromatin remodelling complex, one of the SWI/SNF family of remodellers in human cells. The ARID1A gene is frequently mutated in cancer (Harrod et al., 2020) ARID1A plays a key role in localising BAF to regulatory elements, especially enhancers. Read more
 Supervisor: Prof J Downs
 16 November 2026  PhD Research Project  Funded PhD Project (Students Worldwide)
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Understanding replication stress at human telomeres

Human telomeres are composed of repetitive DNA bound by a protein complex called shelterin, forming a nucleoprotein cap that prevents the natural chromosome ends from fusing together in response to DNA repair. Read more
 Supervisor: Dr M Douglas
 16 November 2026  PhD Research Project  Funded PhD Project (Students Worldwide)
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