We have 12 MRC Laboratory of Medical Sciences (LMS) PhD Projects, Programmes & Scholarships

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MRC Laboratory of Medical Sciences (LMS) PhD Projects, Programmes & Scholarships

We have 12 MRC Laboratory of Medical Sciences (LMS) PhD Projects, Programmes & Scholarships

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Long-term effects of GLP-1 medicines on immunometabolic fitness

MRC Laboratory of Medical Sciences (LMS)
Postgraduate Studies
GLP-1 medicines are transforming the treatment of obesity and related complications, with benefits that extend beyond weight loss and glucose control. Read more
 Supervisors: Dr CK Wong, Dr W Scott
 18 November 2026  PhD Research Project  Funded PhD Project (Students Worldwide)
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Spatial and three-dimensional genome regulation during zygotic genome activation

MRC Laboratory of Medical Sciences (LMS)
Postgraduate Studies
Zygotic genome activation (ZGA) marks the transition from maternal to embryonic control of development and provides a tractable system in which to examine how regulatory genome function is established (1). Read more
 Supervisors: Dr J Vaquerizas, Dr A Russell
 18 November 2026  PhD Research Project  Funded PhD Project (Students Worldwide)
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Designing peptides to uncover cancer vulnerabilities at telomeres

MRC Laboratory of Medical Sciences (LMS)
Postgraduate Studies
How do cells copy chromosome ends whose protection depends on restricting access to DNA? Telomeres are protected by shelterin, a protein complex that prevents chromosome ends from being mistaken for broken DNA. Read more
 Supervisors: Prof C Speck, Dr A Barnard, Dr A Barr
 18 November 2026  PhD Research Project  Funded PhD Project (Students Worldwide)
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How to find and design bioactive peptides at scale?

MRC Laboratory of Medical Sciences (LMS)
Postgraduate Studies
Plants evolved thousands of cyclic peptides to protect themselves against pests and pathogens. Many of these molecules evolved to be orally active. Read more
 Supervisors: Dr K Sarkisyan, Prof D Craik, Dr A Brown
 18 November 2026  PhD Research Project  Funded PhD Project (Students Worldwide)
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Reading tissue history and exposures using spatial single-cell genomics

MRC Laboratory of Medical Sciences (LMS)
Postgraduate Studies
Every cell carries a record of its past. Somatic mutations and DNA methylation changes accumulate as cells divide and as tissues encounter chemicals in the environment, leaving marks that reveal how tissues are built, maintained, and damaged [1,2,3]. Read more
 Supervisors: Dr A Russell, Dr T Coorens
 18 November 2026  PhD Research Project  Funded PhD Project (Students Worldwide)
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Pluripotency-specific regulation of transposable elements in mammalian development

MRC Laboratory of Medical Sciences (LMS)
Postgraduate Studies
In early development, a single fertilized zygote proceeds through a series of cleavage steps to develop into a multicellular blastocyst. Read more
 Supervisors: Dr M Percharde, Dr V Azuara
 18 November 2026  PhD Research Project  Funded PhD Project (Students Worldwide)
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Mutate, model, predict: uncovering how regulatory elements encode gene expression dynamics

MRC Laboratory of Medical Sciences (LMS)
Postgraduate Studies
How does our genome ensure that the right genes are expressed in the right cells and at the right time during development? Although much of this control is encoded in non-coding, cis-regulatory elements, we still lack the ability to predict how regulatory DNA contributes to precise gene expression outputs. Read more
 Supervisors: Dr V Metzis, Dr R Perez-Carrasco, Dr J Ware
 18 November 2026  PhD Research Project  Funded PhD Project (Students Worldwide)
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The Double-edged Sword of Sex-specific Immune Responsiveness

MRC Laboratory of Medical Sciences (LMS)
Postgraduate Studies
Female individuals are better able to cope with certain infections. On the other hand, females suffer from autoimmune diseases significantly more often than males1. Read more
 Supervisors: Prof M Merkenschlager, Dr L Allou
 18 November 2026  PhD Research Project  Funded PhD Project (Students Worldwide)
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Fuelling proliferation: how transporters control metabolism in development and cancer

MRC Laboratory of Medical Sciences (LMS)
Postgraduate Studies
Many cancers lose their differentiated identity and revert to a stem cell-like state. This project asks whether they do so in part by reactivating the metabolic programmes that drive growth in early development, and whether membrane transporters are important regulators of this. Read more
 Supervisors: Dr L Fets, Dr M Percharde
 18 November 2026  PhD Research Project  Funded PhD Project (Students Worldwide)
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Engineered proteins to protect plants and animals from parasites

MRC Laboratory of Medical Sciences (LMS)
Postgraduate Studies
We are discovering and designing proteins that selectively kill invertebrate pests and parasites but are safe for humans and other animals. Read more
 Supervisors: Dr A Brown, Dr K Sarkisyan
 18 November 2026  PhD Research Project  Funded PhD Project (Students Worldwide)
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Quantifying drug response in cancer using 4D using Oblique Plane Microscopy and Optical Coherence Tomography

MRC Laboratory of Medical Sciences (LMS)
Postgraduate Studies
Heterogeneity in drug response is a confounder to successful cancer treatment. Even within genetically identical populations, cells respond differently to drugs due to factors including stochasticity in gene expression, cell cycle phase/state and the environment. Read more
 Supervisors: Dr A Barr, Prof C Dunsby, Dr S Ros
 18 November 2026  PhD Research Project  Funded PhD Project (Students Worldwide)
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MRC Laboratory of Medical Sciences fully funded studentships

MRC Laboratory of Medical Sciences (LMS)
Postgraduate Studies
The MRC LMS is a core-funded transdisciplinary research institute where scientists and clinicians collaborate to advance the understanding of fundamental biology and its relevance to human health. Read more
 Funded PhD Programme (Students Worldwide)  PhD Opportunities
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