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  Marie Curie Early Stage Researcher (PhD) in Quantitative T Cell Immunology: investigating the dynamics and lineage of T stem cell memory T cells in humans


   Department of Infectious Disease

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Dr B Asquith  No more applications being accepted  Funded PhD Project (European/UK Students Only)

About the Project

An exciting opportunity has arisen for an Early Stage Researcher in Quantitative T Cell Immunology in the Department of Medicine, Imperial College London.

You will join a new interdisciplinary project headed by Dr Becca Asquith, carrying out experimental research on the dynamics, lineage and generation of stem cell memory T cells in humans. You will be part of the European Union funded H2020 Programme Initial Training Network, which involves Universities, Research Institutes and industrial companies across Europe. You will be one of a cohort of 15 Early Stage Researchers and will undergo training together and attend joint network-wide events. The position includes funding for home/EU PhD tuition fees.

You will be a dedicated member of the group who will perform experimental work (including stable isotope labelling, flow cytometry and RNAseq) to investigate the dynamics and lineage of T stem cell memory T cells in humans. You will work closely with mathematicians to model and interpret the data.


You must hold a good first degree in Biology, Biomedicine or other appropriate discipline. You must have knowledge of basic research methods and statistical procedures in immunology and experience in a research laboratory environment. Experience of flow cytometry is desirable.

The post is full-time fixed-term for 3 years.


Eligibility

The position is funded by the European Union under the Horizon 2020 Programme. Candidates must be eligible to be appointed as an Early Stage Researcher in the UK. You will have, at the time of recruitment, less than four years full-time equivalent research experience and have not yet been awarded a doctoral degree.
Full-time equivalent research experience is measured from the date when a researcher obtained the degree which would formally entitle him or her to embark on a doctorate, either in the country in which the degree was obtained or in the country in which the researcher is recruited or seconded, irrespective of whether or not a doctorate is or was ever envisaged.

Additionally, you should, at the time of recruitment, not have resided or carried out your main activity (work, studies, etc.) in the UK for more than twelve months in the three years immediately prior to the date of recruitment). There are no nationality restrictions but the post only covers home/EU PhD tuition fees, if you are not eligible for home/EU fees and wish to undertake a PhD you must fund the difference between overseas and home/EU fees.

To apply please visit http://www.imperial.ac.uk/jobs/description/MED00598/early-stage-researcher-quantitative-t-cell-immunology
Please note: In a cover letter, please include a section marked eligibility in which you state (1) the number of months you have worked/resided in the UK in the last 3 years (2) how many years full time research experience you have had since completing your degree.

Project supervisors

Career overview

Professor Becca Asquith has a background in theoretical physics, holding a BSc in Physics with first-class honours from University College London, an MSc in Mathematics with distinction from Imperial College London, and a PhD in Theoretical Particle Physics from the University of Durham, with a thesis titled ''Non Commutative Geometry.'' Following her academic training, she worked as a mathematical modeller for the UK government for two years before transitioning to the field of Mathematical Immunology. Professor Asquith held a Wellcome Trust Fellowship at Imperial College London and subsequently a Leverhulme Trust Fellowship at the University of Oxford. She returned to Imperial College London as a lecturer and is now a Professor of Mathematical Immunology in the Department of Infectious Disease within the Faculty of Medicine. Her research employs a novel combination of experimental, mathematical, and bioinformatic techniques to investigate cell-mediated immunity, with the aim of developing a predictive mathematical model of the human in vivo CD8+ T cell response to prevent and alleviate viral infections.


Research interests

Professor Asquith''s research employs a novel combination of experimental, mathematical, and bioinformatic techniques to investigate cell-mediated immunity. Their primary aim is to develop a predictive mathematical model of the human in vivo CD8+ T cell response to prevent and alleviate viral infections. Professor Asquith has a background in theoretical physics, holding a BSc in Physics, an MSc in Mathematics, and a PhD in Theoretical Particle Physics. They have transitioned from mathematical modelling for the UK government to the field of Mathematical Immunology, having held fellowships with the Wellcome Trust and the Leverhulme Trust.

View Prof. Becca Asquith's profile