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We have 38 antibiotic resistance PhD Projects, Programmes & Scholarships

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antibiotic resistance PhD Projects, Programmes & Scholarships

We have 38 antibiotic resistance PhD Projects, Programmes & Scholarships

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Dissecting the molecular mechanisms of antibiotic resistance in bacterial pathogens

  Research Group: School of Molecular and Cellular Biology
Antibiotics make possible the treatment and cure of life-threatening bacterial infections. Since their introduction in the middle years of the 20th Century, they have added ~10 years to the human lifespan, and have become a cornerstone of modern medicine. Read more
 Supervisor: Prof A O'Neill
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The role of Efflux in Antibiotic Resistance of Clinically Relevant Pathogens

Antibiotics underpin all of modern medicine; they are used to treat bacterial infections, and to prevent infections after surgery and in patients with a suppressed immune system such as those undergoing cancer chemotherapy or organ transplantation. Read more
 Supervisor: Prof J Blair
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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How can DNA condensate despite its negative charge? Implications in genome regulation, antibiotic resistance and gene therapy

  Research Group: Physics of Life
DNA molecules, being highly negatively charged, naturally repel each other. However, in the presence of multivalent ions or specific proteins, they can overcome this repulsion and condense into compact structures. Read more
 Supervisor: Dr AN Noy
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Molecular characterization of suicidal phage-resistance mechanisms in bacteria

Importance. The proliferation of antibiotic resistance (AMR) through horizontal-gene-transfer (HGT) is a formidable health challenge, accounting for 700,000 deaths annually1. Read more
 Supervisors: Dr A Koyamangalath Vadakkepat , Dr M Clokie
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Utilizing machine learning to decipher the mechanism of protein-DNA binding

  Research Group: Division of Evolution, Infection and Genomic Sciences
Transcriptional gene regulation, or the ability to control the timing and levels of gene expression through binding of transcription factors (TFs) to DNA, is a defining feature of life. Read more
 Supervisors: Dr M Lagator, Prof S Lovell, Prof M Rattray
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Bioinformatics analyses of microbial communities and their genetic contents to understand the transmission dynamics and selection of antimicrobial resistance

Project Overview. Antimicrobial Resistance (AMR) is one of the topics that we cannot ignore. Bacterial infections unsuccessfully treated due to AMR claim at least 700 000 lives per year worldwide and are projected to be associated with the deaths of 10 million people per year by 2050. Read more
 Supervisor: Dr S Gweon
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Revolutionising antimicrobial susceptibility testing to optimise treatment of bacterial infection and overcome AMR

  Research Group: School of Molecular and Cellular Biology
Antimicrobial susceptibility testing (AST) is an essential component of the diagnostic workflow in the clinical microbiology laboratory, since it is able to define which antibiotics have the potential to treat bacterial infection in a given patient. Read more
 Supervisor: Prof A O'Neill
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Antimicrobial resistance and gene regulation in Enteroaggregative Escherichia coli.

Details of the Project. Enteroaggregative Escherichia coli (EAEC) is a major cause of diarrhoeal disease in industrialized and non-industrialized countries and has been shown to be the cause of travellers’ diarrhoea and persistent diarrhoea in children and HIV patients. Read more
 Supervisor: Dr DB Browning
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Investigating Non-thermal ‘Cold’ Plasmas for Enhancing the Delivery and Efficacy of Antibiotics and Complex molecules to biofilms of clinically relevant bacteria

  Research Group: Infection and antimicrobial resistance
Biofilms, complex multi-species consortia of microorganisms existing either as surface attached communities or non-surface-attached aggregates, are characterised by significantly elevated tolerance to antimicrobial challenges and often an inability to adequately treat the infection with conventional antibiotics. Read more
 Supervisors: Prof B Gilmore, Dr T Thompson
 Year round applications  PhD Research Project  Funded PhD Project (UK Students Only)
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Developing adjuvants to improve the antibacterial efficacy of fusidic acid: a novel approach to Antimicrobial Resistance?

Background. The antibiotic fusidic acid (FA) blocks bacterial protein synthesis by interacting with Elongation-factor G (EF-G). Resistance to FA is caused by FusB, which interacts with EF-G, altering its motion. Read more
 Supervisors: Dr K Simmons, Dr M McPhillie, Dr J.H. Tomlinson
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Engineered Self-Assembled Medical Scaffolds: Properties, Modification, and Application Testing

Project Advert. Are you interested in developing novel degradable structures to address antimicrobial resistance?. Antimicrobial resistance is a current threat to the recovery of patients. Read more
 Supervisor: Dr MW Wadge
 25 June 2026  PhD Research Project  Funded PhD Project (UK Students Only)
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Turning bacterial metabolism against antimicrobial resistance

  Research Group: Pletzer lab
Background. Antibiotic-resistant infections are becoming increasingly difficult to treat, particularly those caused by Gram-negative bacteria such as Pseudomonas aeruginosa. Read more
 Supervisor: Dr D Pletzer
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Engineering recombinant non-pathogenic bacteria to express antigens from pathogenic species for vaccine development

Bacterial infections pose major health challenges for humans and animals worldwide. The treatment of many such infections is becoming increasingly difficult due to the rise of antibiotic resistance. Read more
 Supervisor: Prof Y Daiwen
 15 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Revolutionising Infection Diagnosis Through Targeted Radiometal Imaging

Please read the Funding note before contacting/applying. Background of the Project. People with conditions like heart disease, diabetes, cancer, organ transplants, or immunodeficiencies face higher risks of infection, complications, and death. Read more
 Supervisor: Dr V Abbate
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating pathogenicity in zoonotic Streptococcus suis

This project offers an exciting opportunity to join a large European consortia and make a tangible impact on a global animal and human health issue. Read more
 Supervisor: Dr L Weinert
 Year round applications  PhD Research Project  Self-Funded PhD Students Only

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