Cell-cell communication is vital to all multicellular life and key in diseases such as cancer. In this PhD project, you will devise new strategies to design advanced biomaterials that guide cell-cell communication for tissue repair or to interfere with diseases such as cancer metastasis or chronic inflammation.
Our DNA is constantly under threat from damaging agents. If unrepaired this DNA damage can lead to errors during genome duplication, including the mutations that can lead to cancer and other human diseases.
In humans, the cysteine-containing tripeptide glutathione (GSH) is an essential thiol cofactor that maintains an intracellular reducing environment to protect against oxidative stress reactive oxygen species, which cause lipid, protein & DNA damage.