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We have 192 biochemistry PhD Projects, Programmes & Scholarships

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biochemistry PhD Projects, Programmes & Scholarships

We have 192 biochemistry PhD Projects, Programmes & Scholarships

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Advancing Untargeted Metabolomics through a Probabilistic and Context-Aware Annotation Pipeline

This project aims to develop a revolutionary AI-powered, "context-aware" pipeline to automate metabolite annotation in untargeted metabolomics data. Read more
 Supervisors: Dr F Del Carratore, Prof WB Dunn, Prof A Jones
 Year round applications  PhD Research Project  Funded PhD Project (UK Students Only)
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MSc by Research: Molecular mechanisms underlying aphid effector virulence activity

Pests and diseases are a major threat to food security with losses ranging between 20-40%. Aphids are one of the most devastating insect pests, globally. Read more
 Supervisor: Dr J Bos
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Molecular Glues for ALS: Restoring TDP-43 Localization for drug discovery

Proteins rarely function in isolation; instead, they form biomolecular complexes by interacting with other biomolecules, including DNA, RNA, and proteins. Read more
 Supervisors: Dr P Cossar, Dr L McGurk
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Deciphering the ubiquitin codes that regulate protein degradation

Ubiquitin signalling, which involves the posttranslational modification (PTM) of proteins with ubiquitin, regulates almost every aspect of eukaryotic biology. Read more
 Supervisor: Prof Y Kulathu
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Trimming the fat - Identification of de-S-acylating enzymes from plants

Protein S-acylation is a reversible fatty acid-based post-translational modification of proteins. Read more
 Supervisors: Dr P Hemsley, Dr J Bos
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Characterisation of human induced pluripotent stem cell derived kidney organoid system for use in drug discovery

Only 5% of all drugs tested in animal models are approved for human applications. Most of these failures are due to unexpected toxicity or lack of efficacy. The poor translation from small mammal studies to humans often causes this challenge. Read more
 Supervisor: Dr PD Davies
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Targeting ‘Undruggable’ Oncoproteins via Induced Proximity

Many well-established cancer drivers, such as K-Ras and β-catenin, have long been considered ‘undruggable’, as traditional drug development approaches have failed to effectively inhibit their activity. Read more
 Supervisors: Prof G Sapkota, Dr S Virdee
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Exploring temperature sensing pathways in barley

Mean global temperatures have risen by 1.5°C above pre-industrial levels and could climb by another 4°C by 2100. Read more
 Supervisor: Dr M Balcerowicz
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Unravelling the molecular mechanism underpinning Ubiquitin-like fusion protein proteolysis

The Maniaci Lab tackles one of the big puzzles in cell biology. Read more
 Supervisor: Dr C Maniaci
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Discovering the Biological Role(s) and Proteomic Impact of Non-Canonical Ubiquitylation

Ubiquitylation, the process by which the small protein ubiquitin is attached to target proteins, is a fundamental post-translational modification… Read more
 Supervisor: Dr V De Cesare
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: The forward facing path: epidermal development in cereals

Plants living on land face brutal threats from pests, dehydration and temperature. To survive and thrive, land plants evolved a waxy ‘cuticle’ and distinctive epidermal cells such as gas pores and defensive barbs. Read more
 Supervisor: Dr S McKim
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Bacillus subtilis intraspecies interactions

Interbacterial competition is ubiquitous and plays a key role in shaping diverse microbial communities, including the gut microbiota and in the rhizosphere. Read more
 Supervisors: Prof N Stanley-Wall, Dr S Coulthurst
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Identifying and studying interacting proteins that are “glue-able” to small molecules

Recent advances from the Ciulli Lab and others have contributed to the establishment of a transformative new modality of chemical intervention into biological system – one that moves beyond the state-of-the-art. Read more
 Supervisor: Prof A Ciulli
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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In-cell quantification of drug concentrations by using advanced nano-sensor

In-cell quantification of drug concentrations is fundamentally important to drug function, efficacy and toxicity, and for understanding and accurately predicting drug interactions and inter-subject variability in drug response (either on-target or off-target effects). Read more
 Supervisor: Dr YG Ge
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Untangling how Metal Dyshomeostasis Pathologically Interacts with Protein Aggregates to Drive Neurodegeneration

Lewy Body Dementia (LBD) consists of two syndromes, Dementia with Lewy Bodies (DLB) and Parkinson’s Disease with Dementia (PDD). Cognitive and motor symptom order differs, but phenotypes eventually converge. Read more
 Supervisor: Dr I Pienaar
 Year round applications  PhD Research Project  Self-Funded PhD Students Only

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