The potential of natural phage communities in biofilm degradation
Research Group:
CENTA - Central England NERC Training Alliance
Dr E Jameson, Dr F Harrison
Application Deadline:
1 May 2019
Project Highlights. Examine the structure of phage communities from a range of environments with metagenome sequencing. Construct a synthetic model biofilm in the laboratory, which is representative of waste water treatment biofouling.
Decoding microbial ‘cross talk’ in polymicrobial infections
Dr N Bandara, Dr A Nobbs
Applications accepted all year round
A significant proportion of human infections are caused by microbial pathogens. These organisms interact socially to build highly organized, well-coordinated, hierarchical structures known as biofilms.
New antimicrobial agents for biofilm-related infections
Dr K Fairfull-Smith
Applications accepted all year round
The adhesion of bacteria to surfaces and their subsequent ability to aggregate into colonies called biofilms is a significant problem in healthcare systems around the world.
Advanced dental plaque biofilm modelling
Prof SM Higham, Dr AC Darby
Application Deadline:
31 May 2019
The oral cavity is highly populated with bacterial species, and around 700 oral bacterial species have been identified. Dental plaque is related to the aetiology of two of the most prevalent disease.
Growth of a bacterial biofilm
Dr M Mazza
Application Deadline:
1 June 2019
The vast majority of living organisms are microorganisms such as bacteria and archaea. We now know that most microorganisms do not live in the planktonic state, but rather in organized communities called biofilms.
Mechanisms of Streptococcus biofilm and community development
Dr A Nobbs
Applications accepted all year round
Streptococcus bacteria are opportunistic pathogens and ubiquitous colonisers of the human oral cavity and mucosae. They are often prominent members of the resident microbiota at these sites, reflecting their evolutionary adaptation to successful colonisation of their ecological niche.
Biofilm Engineering for Healthcare Applications
Dr AF Taylor, Dr E Karunakaran
Applications accepted all year round
Biofilms are communities of microorganisms bound to surfaces by a layer of glue-like extracellular polymeric substances (EPS). They can be found virtually everywhere, from water pipes and food packaging to medical devices and human tissues.
Chronic Wounds and Infection - impact on diabetic patients
Research Group:
Centre for Skin Sciences
Dr M J Thornton, Dr J N Fletcher
Applications accepted all year round
Non-healing chronic wounds present a significant clinical challenge. In Europe, the cost of wound management accounts for 2%–4% of the health care budget and the complications associated with impaired wound healing can have a significant, long-term effect on the morbidity, mortality, and quality of life for patients.
