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biology PhD Projects, Programmes & Scholarships

We have 1,183 biology PhD Projects, Programmes & Scholarships

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The epigenomic, transcriptional and diagnostic architecture of neurodevelopmental disorders caused by exposure to maternal infection

A fundamental unknown in understanding mechanisms of disease, and therefore improving therapy, is how stressors experienced during critical developmental periods influence the genesis or ‘programming’ of adult disease (Estes & McAllister 2016). Read more
 Supervisors: Dr R Hager, Dr M Harte, Dr J Glazier
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Studying novel neurodevelopmental diseases associated with genome instability

Defective DNA repair is a major driver of genetic instability and cancer development. This PhD project, based in Professor Stewart’s laboratory, will investigate how cells detect and repair DNA damage, and how defects in these processes give rise to human disease. Read more
 Supervisor: Prof G Stewart
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Brain cell membrane-coated nanoparticles co-delivering nanozymes and inflammation modulators for the treatment of post-ischaemic stroke injury

  Research Group: Division of Pharmacy & Optometry
Ischaemic stroke remains a leading cause of mortality and long-term disability worldwide. Read more
 Supervisors: Dr CT Tapeinos, Dr H A. Prag
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating Epilepsy Molecular Mechanisms in Patient-Specific Stem Cell Models of SLC6A1 Deficiency

SLC6A1 encodes GAT-1, a voltage-dependent gamma-aminobutyric acid (GABA) transporter that is responsible for the reuptake of GABA from the synapse which are mainly found in the astrocytes. Read more
 Supervisors: Dr M Alsaqati, Dr O Al Musaimi
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating microbiome associations with clinical manifestations of systemic sclerosis

  Research Group: Division of Pharmacy and Optometry
Systemic sclerosis (SSc), or scleroderma, is a rare rheumatological disease characterised by immune dysregulation, vascular dysfunction, and progressive tissue fibrosis affecting the skin and internal organs. Read more
 Supervisors: Prof A McBain, Dr M Hughes
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Why do some people escape genetic risk? Multi-biobank study of immune-mediated inflammatory diseases

  Research Group: Division of Musculoskeletal and Dermatological Sciences
Most people at high genetic risk of immune-mediated inflammatory disease never develop disease, while some develop disease despite apparently low inherited risk. Read more
 Supervisors: Dr SZ Zhao, Dr J Bowes, Prof A Morris
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Viral regulation of host cell signalling pathways

The study of human adenoviruses has been fundamental towards our understanding of many of the molecular pathways that underlie cellular processes such as cell growth and cell death. Read more
 Supervisor: Dr A S Turnell
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Unravelling the Role of Aspergillus in Chronic Airway Disease Exacerbations and Disease Progression

  Research Group: Division of Evolution, Infection and Genomic
Background. Exacerbations are a major health burden of chronic airway disease such as COPD or bronchiectasis. Read more
 Supervisors: Dr CK Kosmidis, Dr A.M Mathioudakis, Dr M Bertuzzi
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Luminescent Anion Receptors for High-Throughput Bioassays in Drug Discovery (Ref: CM/SB-SF2/2026)

The aim of this PhD project is to synthesise luminescent molecules that bind reversibly to target biological anions, which are produced during pharmaceutically important enzyme reactions. Read more
 Supervisors: Dr S Butler, Prof B Buckley
 1 February 2027  PhD Research Project  Self-Funded PhD Students Only
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Turbocharging T cell therapeutics for solid cancer

  Research Group: Division of Immunology, Immunity to Infection and Respiratory Medicine
T cell–based immunotherapies have shown promise for certain malignancies, yet multiple factors limit their effectiveness in solid tumors. Read more
 Supervisors: Dr A Hurlstone, Dr KM Marie, Prof A Malliri
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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PhD Position: Improving Evaluation Frameworks for Microscopy Image Analysis

  Research Group: Centre for Biomedical Image Analysis (CBIA), FI MU
PhD Position. Improving Evaluation Frameworks for Microscopy Image Analysis. Faculty of Informatics, Masaryk University (FI MU), Brno, Czech Republic. Read more
 Supervisor: Assoc Prof PaM Matula
 30 November 2026  PhD Research Project  Funded PhD Project (Students Worldwide)
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Investigate the molecular mechanism controlling FEME (Fast Endophilin Mediated Endocytosis) in cancer cell migration using CRISPR, biochemistry, and advanced microscopy methods.

Cancer is a devastating disease. more than one in three people in the UK will develop cancer in their lifetime. Metastasis is the primary cause of cancer related deaths. Read more
 Supervisor: Dr M Krause
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Studying microRNA landscape during spinal cord regeneration

  Research Group: Division of Molecular and Cellular Function
The human spinal cord (SC) has limited regenerative capacity, and no effective therapies exist to restore function after spinal cord injury (SCI), resulting in severe disability and low quality of life and life-expectancy. Read more
 Supervisors: Dr X Soto Rodriguez, Dr P.S. Slater, Dr K Dorey, Dr A.M. Martín
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the role of Post-Translational Modifications in Mcl-1 in macrophage host defense against bacteria in chronic lung disease

Regulation of Mcl-1 in Macrophage Host Defense. This PhD project offers an opportunity to explore immunometabolism and cell signaling, focusing on how macrophages decide whether to live or die to protect the host. Read more
 Supervisors: Dr H Marriott, Dr J Cole
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Beyond H3K4 Methylation: Mechanistic Insights into How KMT2D Controls Transcription, DNA Repair and Genome Stability

Details of the Project. KMT2D is one of the most frequently mutated genes in human cancer, with recurrent loss-of-function alterations in lymphoma, bladder, colorectal and gastric tumours, and is the causative gene in Kabuki syndrome. Read more
 Supervisors: Dr TK Kantidakis, Dr BK Kysela
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)