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biology PhD Projects, Programmes & Scholarships

We have 1,183 biology PhD Projects, Programmes & Scholarships

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Point-of-care platelet diagnostics

Project Overview. Platelets are small blood cells that play a vital role in the chronic and acute progression of Cardiovascular Disease (CVD), but also have roles in immunity, inflammation, cancer metastasis, Alzheimer's disease and a range of infections, such as dengue, HIV-1, malaria, and COVID-19. Read more
 Supervisor: Dr CI Jones
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Platelets in health, ageing and disease: new diagnostics and treatments

Platelets are small blood cells that play a vital role in the chronic and acute progression of Cardiovascular Disease (CVD), and also have roles in immunity, inflammation, cancer metastasis, Alzheimer's disease and a range of infections, such as dengue, HIV-1, malaria, and COVID-19. Read more
 Supervisor: Dr CI Jones
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Exploring the therapeutic potential of a novel Botulinum toxin

Clostridial neurotoxins are produced by anaerobic bacteria such as Clostridium botulinum. Each toxin molecule has a highly conserved zinc-dependent protease domain that cleaves SNARE proteins, a family of molecules required for intracellular trafficking and vesicle fusion. Read more
 Supervisors: Prof A Peden, Prof J King
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Identifying novel genes and pathways regulating human telomere length

  Research Group: Cardiovascular Sciences
Telomeres are protein bound stretches of repetitive DNA at the end of linear chromosomes that prevent the end of the DNA being incorrectly recognised as a DNA break. Read more
 Supervisors: Dr V Codd, Dr CN Nelson
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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From metabolism to immunity: rediscovering SGLT2

  Research Group: Cardiovascular Sciences
SGLT2 inhibitors are widely prescribed for type 2 diabetes, yet their true potential may extend far beyond blood sugar control. Clinical trials have already shown that these drugs reduce cardiovascular events, protect the kidney, and improve survival. Read more
 Supervisor: Dr EA Akalestou
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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SGLT2 inhibitors and mitochondrial function: a new avenue for an existing drug

  Research Group: Cardiovascular Sciences
Sodium–glucose cotransporter 2 (SGLT2) inhibitors are an established class of antidiabetic drugs that have demonstrated additional benefits beyond glycaemic control, including cardiovascular and renal protection. Read more
 Supervisors: Dr EA Akalestou, Dr LAB Baker
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating the roles that G protein coupled receptors play in hypertension

  Research Group: Molecular & Cell Biology
G protein-coupled receptors (GPCRs) constitute a very large family of heptahelical, integral membrane proteins that mediate a wide variety of physiological processes ranging from the transmission of light and odorant signals to the mediation of neurotransmission and hormonal actions. Read more
 Supervisor: Dr J Willets
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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From Genes to Signals: Visualising Molecular Interactions in Bacterial Communities

  Research Group: Microbiology and Infection
Microbial communities are shaped by dynamic interspecies interactions that influence gene expression, metabolite production, and ecological behaviour. Read more
 Supervisors: Dr K Schilcher, Dr Y Markaki
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Aldehyde dehydrogenase expression and function in cancer stem cells

Aldehyde dehydrogenases (ALDHs) catalyse the oxidation and detoxification of reactive endogenous and exogenous aldehydes into carboxylic acids via NAD+ coupled reduction. Read more
 Supervisors: Prof K Pors, Dr S Swaroop, Dr A Ruiz Estrada
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Greasing plant cell signalling – the role of S-acylation in plant receptor cytoplasmic kinase signalling during immune responses

Protein S-acylation is a reversible fatty acid-based post-translational modification of proteins. Read more
 Supervisors: Dr P Hemsley, Dr J Bos
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Human heart organoids for drug discovery in heart failure

Study of heart failure and heart attack is extremely difficult. Moreover, only 5% of all drugs tested in animal models are approved for human applications. Read more
 Supervisor: Dr PD Davies
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Exploring temperature sensing pathways in barley

Mean global temperatures have risen by 1.5°C above pre-industrial levels and could climb by another 4°C by 2100. Read more
 Supervisor: Dr M Balcerowicz
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Smart Switchable Sensors for On Demand Biosensing and Cell Therapy Monitoring

Cell and gene therapies are transforming medicine by enabling personalised treatments for patients with cancer and other life-threatening diseases. Read more
 Supervisor: Prof P Mendes
 Year round applications  PhD Research Project  Funded PhD Project (UK Students Only)
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Next Generation Glycan Sensing for Early Cancer Diagnosis

Early diagnosis remains one of the greatest challenges in cancer treatment. Subtle molecular changes often occur long before clinical symptoms appear, yet existing diagnostic tools struggle to detect them with sufficient sensitivity and accuracy. Read more
 Supervisor: Prof P Mendes
 Year round applications  PhD Research Project  Funded PhD Project (UK Students Only)
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MSc by Research: Discovering the Biological Role(s) and Proteomic Impact of Non-Canonical Ubiquitylation

Ubiquitylation, the process by which the small protein ubiquitin is attached to target proteins, is a fundamental post-translational modification… Read more
 Supervisor: Dr V De Cesare
 Year round applications  PhD Research Project  Self-Funded PhD Students Only