computational biology PhD Projects, Programmes & Scholarships

We have 167 computational biology PhD Projects, Programmes & Scholarships

Targeting the mechanism of small GTPase splice variant RAC1B using ligand design

The University of Manchester Faculty of Biology, Medicine and Health

RAC1 is a small GTPase protein that functions as a key signalling node downstream of various microenvironmental signalling pathways. Read more

Supervisors: Dr RB Bryce, Dr S Butterworth, Dr T Jowitt, Dr A Ucar

Year round applications PhD Research Project Self-Funded PhD Students Only

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Understanding the evolution of gene regulatory networks through biophysical modelling and machine learning

The University of Manchester Faculty of Biology, Medicine and Health

The ability to coordinate the expression of genes within a cell is at the heart of life. When and how much of a specific gene is turned into a protein is essential for organisms to respond to their environment and to manage resources. Read more

Supervisors: Dr M Lagator, Prof M Rattray

Year round applications PhD Research Project Self-Funded PhD Students Only

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Supervised learning methods to measure information transfer in biology

University of St Andrews School of Mathematics and Statistics

Information theory is widely used as the basis of communication channels to transfer information through the Internet and other platforms. Read more

Supervisor: Dr G Minas

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Persistent biochemical computation for sense and respond applications

Imperial College London Department of Bioengineering

We invite applications for a UKRI-EPSRC Industrial CASE 4-year PhD studentship, "Persistent biochemical computation for sense and respond applications". Read more

Supervisor: Dr T Ouldridge

31 August 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Structural and mechanistic studies of fibroblast growth factor receptor signalling

University of Leeds Faculty of Biological Sciences

The School of Molecular and Cellular Biology invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more

Supervisors: Prof A.L. Breeze, Prof F. Sobott

Year round applications PhD Research Project Self-Funded PhD Students Only

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Structure and activity of VDR and RARγ, their targeting compounds and complexes

Medical University of Vienna Institute for Pathophysiologie and Allergy

The doctoral candidate (DC) will perform structural biology type research focused on obtaining, purifying and structural analysis of binding domains of VDR and RARγ full receptors, their targeting compounds and complexes formed by these receptors. Read more

Supervisor: Prof KW Woźniak

29 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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In Silico targeting of unstructured extracellular histones: En route to a new horizon of drug discovery to target disordered proteins) – second call for applications

Maastricht University Cardiovascular Research Institute Maastricht (CARIM)

Applications can only be submitted via our website. The specific position for Doctoral Candidate 6 (DC6) in the consortium, which is part of Work Package 2 (WP2), aims. Read more

Supervisor: Dr G Nicolaes

30 April 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Structure-based design of allosteric modulators for G protein-coupled receptors using molecular modelling and pharmacology experiments

Queen’s University Belfast School of Pharmacy

Almost all physiological processes are regulated through the activation of G protein-coupled receptors (GPCRs). It has become widely accepted that most GPCRs possess binding sites spatially distinct from their natural ligand binding site (orthosteric site), termed as allosteric sites. Read more

Supervisors: Dr I Tikhonova, Dr B Plouffe

Year round applications PhD Research Project Self-Funded PhD Students Only

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Systems immunology and multi-omics approaches to understand protective immunity to human malaria

University of Queensland Institute for Molecular Bioscience

This PhD project aims to develop and apply computational approaches that integrate systems biology and molecular immunology to understand host-pathogen immunity and predict immune control of malaria. Read more

Supervisor: Prof D Doolan

Year round applications PhD Research Project Funded PhD Project (Students Worldwide)

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Better together: constructing tuneable fluorescent protein sensors for cellular imaging of protein-protein interactions

Cardiff University Cardiff School of Biosciences

Project Description. Protein-protein interactions (PPIs) commonly occur in biology with ~650,000 contributing to processes critical to human life. Read more

Supervisors: Prof D Jones, Dr PD Watson, Dr G Menzies, Dr R Clarkson

Year round applications PhD Research Project Self-Funded PhD Students Only

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(MRC DTP CASE) Prediction of substrate binding geometry and strength in promiscuous enzymes: computational chemistry applicable to the design of pharmaceuticals and agrochemicals

The University of Manchester Faculty of Biology, Medicine and Health

We are often taught about the power of enzymes to select particular substrates from the biological milieu and of their ability to perform highly selective reactions on those substrates. Read more

Supervisors: Dr A Leach, Dr S De Visser, Dr C Trujillo

13 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Revealing Reactivity in Cancer-Associated Heme Proteins: Novel Time-Resolved Structural Approaches

University of Leicester Molecular and Cell Biology

Indoleamine 2,3-dioxygenase 1 (IDO1) is a heme-containing enzyme involved in the degradation of tryptophan to kynurenine. Cancer cells upregulate IDO1 to escape normal immune responses and, in many cases, a high expression of IDO1 is connected to poor prognosis. Read more

Supervisors: Dr HK Kwon, Dr P A Ash

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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Natural products in bacterial physiology and chemical interaction

University of Leicester Department of Genetics and Genome Biology

Microbial natural products have diverse chemical structures and bioactivities, which range from cell-cell signalling, nutrient acquisition, antifungal and antibacterial activity to stress resistance (1). Read more

Supervisors: Dr C Jenul, Prof D Jones

23 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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(University of Manchester - University of Tokyo Dual Award) Computational evolutionary biomechanics of bipedal/quadrupedal locomotion in early hominids

The University of Manchester Department of Earth and Environmental Sciences

The transition to habitual upright walking is one of the defining features of the human (as opposed to the chimpanzee) lineage and understanding its evolution is therefore of extreme interest to palaeoanthropologists. Read more

Supervisors: Prof W Sellers, Prof N Ogihara

29 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Hungry tissues: Understanding how energy metabolism fuels morphogenesis

The University of Manchester Faculty of Biology, Medicine and Health

A vital aspect of multi-cellular life is morphogenesis, the process where the shape and size of an animal emerges from its constituent cells. Read more

Supervisors: Dr J.R.D Davis, Dr T Millard, Dr S Woolner, Prof E Amaya

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 167 computational biology PhD Projects, Programmes & Scholarships

computational biology PhD Projects, Programmes & Scholarships

We have 167 computational biology PhD Projects, Programmes & Scholarships

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