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We have 159 computational biology PhD Projects, Programmes & Scholarships

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computational biology PhD Projects, Programmes & Scholarships

We have 159 computational biology PhD Projects, Programmes & Scholarships

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MSc by Research: Identifying and studying interacting proteins that are “glue-able” to small molecules

Recent advances from the Ciulli Lab and others have contributed to the establishment of a transformative new modality of chemical intervention into biological system – one that moves beyond the state-of-the-art. Read more
 Supervisor: Prof A Ciulli
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Host Advantage: Uncovering Protective Factors Against HPV‑Driven Cervical Cancers

Who we are looking for. We are seeking a PhD student who is motivated by the process of scientific discovery and the opportunity to identify novel targets for anti-cancer therapies. Read more
 Supervisors: Dr K Spriggs, Dr C de Moor
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Cardiovascular development: Understanding how biomechanical forces regulate heart valve morphogenesis in the embryo

  Research Group: Chow Group
The Project. In the developing embryo, the heart begins as a simple, straight tube that pumps blood inefficiently. As the embryo grows, the heart twists and grows and morphs into a four-chambered organ with intricate cardiac structures. Read more
 Supervisor: Dr R Chow
 Year round applications  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Structural and mechanistic studies of fibroblast growth factor receptor signalling

  Research Group: Astbury Centre for Structural Molecular Biology
We have identified a previously undiscovered ‘signal switching’ mechanism used by a branch of the receptor tyrosine kinase (RTK) family – fibroblast growth factor receptors (FGFRs) – that are important in early development but also oncogenic in a range of cancers. Read more
 Supervisors: Prof A.L. Breeze, Prof F. Sobott
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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How can DNA condensate despite its negative charge? Implications in genome regulation, antibiotic resistance and gene therapy

  Research Group: Physics of Life
DNA molecules, being highly negatively charged, naturally repel each other. However, in the presence of multivalent ions or specific proteins, they can overcome this repulsion and condense into compact structures. Read more
 Supervisor: Dr AN Noy
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Genome control by cohesin ligands

Second Supervisor. Professor Peijun Zhang, Nuffield Department of Medicine University of Oxford. The human genome is metres long but packed into cells only a few micrometres in diameter. Read more
 Supervisor: Prof D Panne
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Anticipating the impacts of extreme weather on biodiversity

Project Overview. To date, efforts to address the impacts of climate change on biodiversity have focused on gradual shifts in species’ abundance and distribution. Read more
 Supervisor: Dr V Boult
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Molecular Mechanisms of Insect Olfaction Toward Sesquiterpenoid Stereoisomers

How do insects distinguish between mirror-image molecules, and why can a subtle change in stereochemistry transform a strong attractant into a compound that elicits no response? This PhD project explores the molecular mechanisms that drive insect recognition of sesquiterpenoid stereoisomers, a class of compounds commonly involved in true bug pheromone communication. Read more
 Supervisor: Dr SJP Park
 25 July 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Defining the impact of chromatin and transcriptional regulator-driven phase separation in cancer cell behaviour.

Oesophageal adenocarcinoma (OAC) is a deadly disease with poor survival statistics, is one of the highest incidence cancer types and is growing in prevalence, particularly in the developing world. Read more
 Supervisors: Prof A Sharrocks, Dr I Iqbal
 15 June 2026  PhD Research Project  Funded PhD Project (UK Students Only)
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Accessing New Chemistries: Tuning Reactivity Of Chemical Processes Using Ionic Liquids And Deep Eutectic Solvents (Ref: CG-AC-2524)

Ionic solvents are known to alter the outcomes of chemical processes by influencing their mechanism. Because of the wide variety of different ions that might make up an ionic solvent, there is enormous scope for tuning these processes. Read more
 Supervisor: Prof A Croft
 3 August 2026  PhD Research Project  Self-Funded PhD Students Only
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Access-Controlled Oxidation: Understanding the role of structure in protein damage (Ref: CG-AC-2526)

Protein oxidation is a major marker of protein damage in aging and disease processes, and can occur through a number of routes. One poorly understood contributing element is how protein structure, including local structure, controls the outcomes of oxidation events in the body. Read more
 Supervisors: Prof A Croft, Prof MJ Davies
 3 August 2026  PhD Research Project  Self-Funded PhD Students Only
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Beyond normal - Proteins in Alien Environments (Ref: CG-AC-2525)

What would happen if the liquid enabling life were not water, but a class of molecules with a similar melting range known as 'ionic liquids'? Ionic liquids are, simply, liquids made of ions usually defined as having melting temperatures below 100C, for which there are millions of possible options. Read more
 Supervisor: Prof A Croft
 3 August 2026  PhD Research Project  Self-Funded PhD Students Only
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Data-driven Approaches to Viscoelastic Flow Control

Many liquids in industry and biology are viscoelastic (like paints, blood, saliva, and DNA suspensions among many others), displaying a mixture of both viscous and elastic properties. Read more
 Supervisors: Dr M Beneitez, Dr J King
 Year round applications  PhD Research Project  Funded PhD Project (UK Students Only)
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Last chance to apply

AI Based Prediction of Splice Site Selection (WUT_U26CMP)

The central dogma of molecular biology describes the flow of genetic information from DNA to RNA and ultimately to protein. Read more
 Supervisor: Dr T Wu
 18 June 2026  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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We are what we eat: Plants and their effects on the brain

Project Overview. Plants synthesize many compounds that can act like hormones in mammals. A class of plant compounds called phytosteroids act like steroid hormones and may influence anxiety, reproduction and healthy aging, though the mechanisms by which these signal are poorly understood. Read more
 Supervisors: Dr N Vasudevan, Prof J A Hawkins
 Year round applications  PhD Research Project  Self-Funded PhD Students Only

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