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We have 18 enzyme engineering PhD Projects, Programmes & Scholarships

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enzyme engineering PhD Projects, Programmes & Scholarships

We have 18 enzyme engineering PhD Projects, Programmes & Scholarships

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Enzyme Cascades controlled in the Electrochemical Leaf for Discovery in Antimicrobial Strategy

Antibiotic discovery is usually aimed at single entities, for example a bacterial enzyme or efflux protein. This also means that antimicrobial resistance (AMR) mechanisms are considered in terms of the individual response, for example, mutations in a single target enzyme, affording resistance to the drug. Read more

High-throughput characterization and engineering of nucleotide synthases for production of nucleoside analogues

Nucleotides are the building blocks of life, modulating diverse processes from protein production to cell signalling. It is therefore unsurprising that synthetic nucleoside analogues have been developed as therapeutics for the treatment of a wide range of diseases including cancers and viral infections. Read more

Towards 3D-printing of self-assembled insect-mimetic acoustic structures

Overview. We are seeking excellent candidates for 4-yr PhD and 5-yr masters+PhD scholarships to pursue an exciting interdisciplinary project that will pioneer novel materials enabled by self-assembly and 3D printing with multiple length-scales of complexity to better mimic the functional structures of insect hearing. Read more

New Methods for modelling cofactor-dependent enzyme structure and function

Enzymes are Nature’s catalysts and many used cofactors and/or coenzymes to catalyse their reactions. While AI and homology methods now often allow the useful prediction of protein structure from amino acid sequence, this can be more challenging when the protein/enzyme contain cofactors. Read more

Protein engineering enzymes for Industry

Project Overview. We are interested in key features of the protein sequence - structure - function relationship, and how this information can be translated to health. Read more

Enzyme-responsive peptide hydrogels as in situ forming long-acting drug delivery implants

One of the key issues in the treatment and prevention of disease is that patients struggle to adhere to the complex dosage regimens of therapies, which often require multiple dosing at very specific times each day. Read more

Synthetic and Mechanistic Studies into Enzymatic Degradation of Waste Plastics

Plastics are a broad range of solid polymeric materials that have found widespread application globally. However, there has been a steady accumulation of discarded plastics and there is now growing awareness that they present a significant hazard to the natural environment and human health. Read more

Pharmaceutical process development, optimization and scale-up of plant-based cancer drugs

Project - We are pleased to announce an exciting PhD opportunity within our ground-breaking project dedicated to the optimization of extraction and purification processes of plant-derived molecules, with potential applications in cancer treatment as a collaborative effort with the South Australian immunoGENomics Cancer Institute. Read more

Gastrointestinal modulation using omega-3 and probiotic strategies and its effect on cardio-metabolic health in obese and non-obese populations

  Research Group: Cambridge Centre for Sport and Exercise Sciences
Research Group. Cambridge Centre for Sport and Exercise Sciences - https://www.anglia.ac.uk/science-and-engineering/research/institutes-and-groups/cambridge-centre-for-sport-and-exercise-sciences. Read more

Mechanisms underlying the effects of activated protein C (APC) in cardiac muscle

  Research Group: Chemistry and Biosciences
APC is an anticoagulant enzyme that also exerts antithrombotic, anti-inflammatory, antiapoptotic and a variety of other cytoprotective effects in different tissues, where the mechanism of action is thought to involve the endothelial protein C receptor (EPCR) and a protease activated receptor (PAR). Read more

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