We have 97 medical research council PhD Projects, Programmes & Scholarships

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medical research council PhD Projects, Programmes & Scholarships

We have 97 medical research council PhD Projects, Programmes & Scholarships

Novel dynamic shape atlasing of cardiovascular structures in congenital heart disease

University of Bristol

Bristol Medical School

Congenital heart disease (CHD) affects 1 in 110 births and causes significant long-term morbidity, yet identifying anatomical sub-phenotypes remains difficult. Read more

Supervisor: Dr G Biglino

21 October 2026 PhD Research Project Funded PhD Project (Students Worldwide)

Mechanism of transcription-coupled splicing

Medical Research Council (Cambridge)

Laboratory of Molecular Biology

Accurate gene expression in eukaryotic cells requires tight coordination between transcription and pre-mRNA splicing. During transcription by RNA polymerase II (Pol II), the spliceosome removes introns from nascent RNAs co-transcriptionally. Read more

Supervisor: Dr S Zhang

8 December 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

Machine learning for finding macromolecules in cells

Medical Research Council (Cambridge)

Laboratory of Molecular Biology

The aim of this PhD project is to develop computer software for in situ structural biology projects. Specifically, software tools for the identification of macromolecular complexes in cryo-EM/cryo-ET data sets collected on thinned human and budding yeast cells. Read more

Supervisor: Dr D Barford

8 December 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

Circuit basis of learning and action-selection

Medical Research Council (Cambridge)

Laboratory of Molecular Biology

The overall goal of our research is to discover the circuit implementation of learning and action selection. Read more

Supervisor: Dr M Zlatic

8 December 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

Transforming Thoughts into Actions

Medical Research Council (Cambridge)

Laboratory of Molecular Biology

How does the brain transform what we perceive into what we do? Even a simple action, such as stopping at a red light and moving again when it turns green, requires the brain to select relevant sensory information, form an intention, prepare an appropriate movement and execute it at the right moment. Read more

Supervisor: Dr M Tripodi

8 December 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

Neuropeptide networks in worms and octopus

Medical Research Council (Cambridge)

Laboratory of Molecular Biology

In recent years, great efforts have been made to map the synaptic wiring diagrams of simple and complex nervous systems. However, chemical synapses, the connections used in most connectomics research, represent only one type of functionally important signalling between neurons. Read more

Supervisor: Dr W Schafer

8 December 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

Lysosomal TMEM106B in brain ageing and disease

Medical Research Council (Cambridge)

Laboratory of Molecular Biology

Our group studies mechanisms of brain health, ageing and disease focusing on the lysosomal protein transmembrane protein 106B (TMEM106B) which forms amyloids in the brain in an age-dependent manner. Read more

Supervisor: Dr D Arseni

8 December 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

Visualizing cellular proteostasis

Medical Research Council (Cambridge)

Laboratory of Molecular Biology

Each cell relies on thousands of internal biochemical reactions, carried out by around ten thousand different types of proteins. These cellular proteins, collectively known as the proteome, must be synthesized in precise quantities, undergo correct folding, and be accurately localized within the cell. Read more

Supervisor: Dr J Fedry

8 December 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

Drugging daily clocks in a dish

Medical Research Council (Cambridge)

Laboratory of Molecular Biology

Many commonly used drugs would benefit from considering daily biological timing but mechanistic understanding of circadian medicine is limited (Cederroth et al). Read more

Supervisor: Dr J O'Neill

8 December 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

Hidden RAS conformations at the membrane

Medical Research Council (Cambridge)

Laboratory of Molecular Biology

RAS proteins are central molecular switches in human signalling and are among the most frequently mutated proteins in cancer. Read more

Supervisor: Dr JS Streit

8 December 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

Protein aggregates and neurodegeneration

Medical Research Council (Cambridge)

Laboratory of Molecular Biology

To understand and ultimately treat neurodegenerative diseases characterised by protein aggregates, one must understand how these aggregates accumulate, how they become toxic to brain cells and the mechanisms which allow them to spread. Read more

Supervisor: Dr H McMahon

8 December 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

Cell division in Asgard archaea

Medical Research Council (Cambridge)

Laboratory of Molecular Biology

Complex cells likely arose from the merger of an archaeal host cell with a bacterial cell some 2 billion years ago. As a consequence, many of the most conserved features of eukaryotic cell biology have their origins in archaea. Read more

Supervisor: Dr B Baum

8 December 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

Connectomics of neural network plasticity

Medical Research Council (Cambridge)

Laboratory of Molecular Biology

Connectomics is the study of biological neural networks at synaptic resolution. The resulting wiring diagrams teach us how information is processed in animal brains, including perception and behaviour [1]. Read more

Supervisor: Dr ST Truckenbrodt

8 December 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

How proteins fold on the ribosome in real time

Medical Research Council (Cambridge)

Laboratory of Molecular Biology

De novo protein folding is the fundamental process by which a polypeptide chain acquires its native conformation for the first time. Read more

Supervisor: Dr IB Bukvin

8 December 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

DNA repair at stalled replication forks

Medical Research Council (Cambridge)

Laboratory of Molecular Biology

Large multiprotein complexes perform many essential functions in eukaryotic cells. My lab purifies, assays and determines structures of these macromolecular machines to understand their mechanisms. Read more

Supervisor: Dr L Passmore

8 December 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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