We have 30 medicinal chemistry PhD Projects, Programmes & Scholarships

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medicinal chemistry PhD Projects, Programmes & Scholarships

We have 30 medicinal chemistry PhD Projects, Programmes & Scholarships

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CRISPR-Cas9 genome editing and super-resolved live cell imaging to study the extracellular microenvironment at the single molecule level

University of Nottingham
School of Pharmacy
The three-dimensional space around and between mammalian cells is filled with a complex network of extracellular matrix (ECM) molecules, which instruct fundamental processes such as cell survival, differentiation and migration, in addition to providing structural support for cells. Read more
 Supervisors: Dr A Piccinini, Prof D Heery, Dr H Collins
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Science Research Opportunities at the University of East Anglia

University of East Anglia
Faculty of Medicine and Health Science
The Faculty of Science is part of Norwich Research Park, one of Europe's leading research centres conducting cutting-edge multidisciplinary research with an annual research spend of over £130 million. Read more
 Funded PhD Programme (Students Worldwide)  PhD Opportunities
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New Platform Motifs for Reaction Discovery: Catalysis tools for sustainable synthesis

University of Birmingham
School of Chemistry
The introduction of new platform motifs enables the development of myriad new chemical transformations and enhanced understanding of reactivity. Read more
 Supervisor: Dr P Davies
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Benzofused Azabicycles and Spiropiperidines via Biocatalytic Oxidation-Cycloaddition Cascades

The University of Manchester
Department of Chemistry
o-Quinoid species (e.g. quinones, quinone imines, quinone methides) are versatile reactive intermediates for the synthesis of a variety of complex molecules.[1-4] They readily undergo a range of reactions including 1,4-conjugate additions, 1,3-oxazole formation, and Diels−Alder cycloadditions. Read more
 Supervisor: Dr L Wong
 31 August 2026  PhD Research Project  Funded PhD Project (UK Students Only)
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Synthesis, Characterisation and Evaluation of Novel Antimicrobial Agents against Polymicrobial Biofilms.

University of Birmingham
School of Dentistry
Antimicrobial resistance (AMR) poses a major global health threat, driven in part by the persistence of polymicrobial biofilms that exhibit high tolerance to antimicrobial treatments and immune defences. Read more
 Supervisors: Dr A R Rahman, Dr L Cox
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Tackling oxaliplatin drug resistance in colorectal cancer by developing a novel bifunctional prodrug

University of Bradford
Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Acquired drug resistance is a considerable problem for the treatment of colorectal cancer (CRC), of which oxaliplatin is a key component, with little improvement in the ~65% 5-year survival rate over the past 25 years. Read more
 Supervisors: Dr S Shnyder, Dr G Ribeiro Morais, Prof R Falconer
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Design, synthesis and evaluation of novel polysialyltransferase inhibitors as anti- metastatic agents

University of Bradford
Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases (polySTs). Read more
 Supervisors: Prof R Falconer, Dr S Shnyder
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Developing novel treatments for invasive fungal infections

University of Strathclyde
Department of Pure and Applied Chemistry
Invasive Fungal Infections. Invasive fungal infections, such as those caused by the fungi Candida, are an increasing global public health concern. Read more
 Supervisor: Dr FS Scott
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The development of new antiviral agents targeting HIV-1

Newcastle University
Faculty of Medical Sciences Graduate School
Even before the current global COVID-19 pandemic, the threat posed to human health by viruses was extensive and although significant progress in targeting some viruses (e.g., HIV-1 and hepatitis C) has been made, challenges remain. Read more
 Supervisor: Dr M Ashton
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Polysialyltransferases as a target in metastatic cancer

University of Bradford
Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Polysialic acid plays an essential role in neuronal development, but by adulthood is absent from the human body. Its biosynthesis is regulated by two polysialyltransferases. Read more
 Supervisors: Prof R Falconer, Dr S Shnyder
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Development of chemical tools and bioactive compounds to explore the importance of enzyme activity in cancer diseases

University of Bradford
Faculty of Life Sciences
Diversity-oriented synthesis (DOS) is a modern chemical methodology, which aims to synthesise small molecules that cover new chemical space with the possibility of finding unexplored biological targets or pathways that may be important for disease progression. Read more
 Supervisors: Prof K Pors, Dr V Jha, Dr Muhammad Wahajuddin
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Accelerating the clinical introduction of novel antibiotic combinations effective against Gram-negative pathogens

University of Strathclyde
Department of Pure and Applied Chemistry
Strathclyde Minor Groove Binders (S-MGB) lead compounds have in vivo activity (MIC 0.2 µg/mL) against Gram-positive bacteria.[1-5] In 2015 our commercial partner, MGB Biopharma, completed the successful Phase I Clinical Trial (NCT02518607) of our lead candidate MGB-BP-3 for the treatment of Clostridium difficile infections. Read more
 Supervisor: Dr FS Scott
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Novel Formulation Strategies for Multi-Drug Delivery Systems to Address Polypharmacy

University of Liverpool
Faculty of Health and Life Sciences
This PhD project aims to develop next-generation multi-therapy drug delivery systems that address polypharmacy by engineering programmable formulations in a single dose that simplify complex drug regimens and transform care for patients with multiple chronic conditions. Read more
 Supervisor: Dr w Lau
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Design, synthesis and evaluation of protease-activated anti-cancer prodrugs

University of Bradford
Faculty of Life Sciences
  Research Group: Institute of Cancer Therapeutics
Matrix metalloproteinases (MMPs) are a family of endoproteases that are overexpressed in tumours and play crucial roles in many tumourigenic processes, not least tumour invasion and angiogenesis. Read more
 Supervisors: Prof R Falconer, Prof P Loadman
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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MSc by Research: Identifying and studying interacting proteins that are “glue-able” to small molecules

University of Dundee
Faculty of Life Sciences
Recent advances from the Ciulli Lab and others have contributed to the establishment of a transformative new modality of chemical intervention into biological system – one that moves beyond the state-of-the-art. Read more
 Supervisor: Prof A Ciulli
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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