We have 30 medicinal chemistry PhD Projects, Programmes & Scholarships

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medicinal chemistry PhD Projects, Programmes & Scholarships

We have 30 medicinal chemistry PhD Projects, Programmes & Scholarships

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Developing first-in-class PROTAC degraders against the HPV E7 oncoprotein

Cardiff University
Cardiff School of Biosciences
Can targeted protein degradation help eliminate cancer-causing viruses?. Human papillomavirus (HPV) is responsible for almost all cervical cancers and approximately 70–80% of HPV-positive throat cancers. Read more
 Supervisors: Dr M Paradowski, Prof A Gallimore, Dr D Jones, Dr N Buurma
 20 August 2026  PhD Research Project  Funded PhD Project (UK Students Only)
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PhD in Chemistry: Medicinal Chemistry of Nucleotide Analogues

Cardiff University
Cardiff School of Chemistry
Nucleoside analogues (NAs) are an important class of antiviral and anticancer agents commonly used in the therapy of many different viral infections and cancer conditions. Read more
 Supervisor: Dr M Serpi
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Synthesis of Fluorinated Heterocycles (Ref: CM/MK-SF2/2026)

Loughborough University
Department of Chemistry
This project will involve synthetic organic chemistry to prepare novel nitrogen heterocyclic compounds based (including pyridones, cinnolines or quinoxalines) using nucleophilic aromatic substitution (SNAr) of fluoroarenes to allow rapid construction of small molecules of interest as drug candidates as antibiotics, anti-cancer agents or against Neglected Tropical Diseases. Read more
 Supervisors: Dr G Weaver, Dr M Kimber
 31 December 2026  PhD Research Project  Self-Funded PhD Students Only
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Computational Design and Study of Peptide-Like Foldamers for Supramolecular and Medicinal Chemistry

University of Aberdeen
School of Natural and Computing Sciences
These projects are open to students worldwide, but have no funding attached. Therefore, the successful applicant will be expected to fund tuition fees at the relevant level (home or international) and any applicable additional research costs. Read more
 Supervisors: Dr L Trembleau, Prof H Deng
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Development of New Chemical Biology Probes for Medicinal Chemistry Applications

University of Strathclyde
Department of Pure and Applied Chemistry
This project will center around the development of novel tool compounds for diseases of societal need, and is collaborative with GSK as an industrial partner. Read more
 Supervisor: Prof C Jamieson
 Year round applications  PhD Research Project  Funded PhD Project (UK Students Only)
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PhD Opportunity in Electrosynthesis for Medicinal and Organic Synthesis

University of Greenwich
Department of Pharmaceutical, Chemical and Environmental Sciences
Location. University of Greenwich, Kent, UK. Duration. 3 years, full-time. The Project. We are seeking an ambitious and talented PhD candidate to join the Lam Research Group at the University of Greenwich, working at the forefront of electrosynthesis, sustainable organic synthesis, and reaction innovation. Read more
 Supervisor: Prof K Lam
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Broadening the spectrum of antibacterial drugs to tackle multi-drug resistant Gram-negative pathogens

University of Leeds
Faculty of Biological Sciences
  Research Group: Astbury Centre for Structural Molecular Biology
Antibiotics make possible the treatment and cure of life-threatening bacterial infections and have added over a decade to average human lifespan. Read more
 Supervisors: Prof A O'Neill, Dr M McPhillie, Prof C Fishwick
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Identifying Novel Therapeutics for the Treatment of Alpha-Synucleinopathies: A Chemistry-Biology Approach to Parkinson's Disease

Newcastle University
Faculty of Medical Sciences Graduate School
The Clinical Challenge. Parkinson's Disease and Protein Aggregation. Parkinson's disease affects approximately 150,000 people in the UK and accounts for around 8,000 deaths annually. Read more
 Supervisor: Dr J Sellars
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Dual Ended HDAC-Bcl-2 Inhibitor Therapeutics (DEHBIT): A Continuous Flow Chemistry Approach to Next-Generation Polypharmacological Cancer Therapeutics

Newcastle University
Faculty of Medical Sciences Graduate School
Background and Scientific Rationale . Cancer remains one of the most significant global health challenges, characterised by complex, multifactorial disease mechanisms requiring equally sophisticated therapeutic strategies. Read more
 Supervisor: Dr J Sellars
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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PhD position available in Synthetic Chemistry for Development of Mitochondria Targeting and Genome Engineering.

Imperial College London
Department of Chemistry
PIONEER (Programmable In-Organelle Nucleic-acid Entry, Expression and Retention) is an ambitious UK research consortium from Imperial College London, the University of Bristol, and the University of Glasgow, funded through the UK’s Advanced Research and Innovation Agency’s (ARIA) Precision Mitochondria programme, with a single bold goal. Read more
 Supervisor: Dr N Kamaly
 31 August 2026  PhD Research Project  Funded PhD Project (European/UK Students Only)
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PRIMED for Medincinal Chemistry (PRecision, AI Informed, Molecular EDiting)

University of St Andrews
School of Chemistry
  Research Group: Rebecca Goss
The PhD focusses on innovative precision molecule editing and diversification. PRIMED combines late stage enzymatic halogenation with synthetic diversification of aryl and alyl halides. Read more
 Supervisor: Prof JM Goss
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Developing Next‑Generation Boron Compounds for BNCT Cancer Therapy

University of Birmingham
School of Pharmacy
We invite applications for a PhD project focused on the design, synthesis and evaluation of novel boron-rich small molecules for Boron Neutron Capture Therapy (BNCT). Read more
 Supervisors: Dr M Jones, Dr J Coverdale, Prof J Parsons
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Preparing for the next pandemic: Design and Synthesis of Novel Broad-Spectrum Antivirals against SARS-CoV-2 and emerging viral threats

University of Nottingham
School of Pharmacy
The covid pandemic was a wake-up call for the need for novel anti-virals, preferably broad-spectrum, to potentially combat future pandemics, but to also better treat those with existing viral infections in both humans and animals. Read more
 Supervisors: Dr LS Schembri, Dr CC Coleman
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Towards the development of a novel class of broad-spectrum anti-infective drugs

University of Strathclyde
Department of Pure and Applied Chemistry
Through exceptionally strong research collaborations at the interface of chemistry, biology, and medicine, we have applied innovative thinking to the field of (Minor Groove Binders) MGBs to develop a novel platform for drug discovery with the potential to treat an impressive range of diseases, including bacterial, fungal, parasitic, and viral infections. Read more
 Supervisor: Dr FS Scott
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigation of the critical roles of platelets at the interface between thrombosis and inflammation in order to develop improved therapeutic strategies for the treatment and/or prevention of cardiovascular/inflammatory diseases

University of Reading
School of Pharmacy
Platelets (small circulating blood cells) are involved in blood clotting to prevent excessive bleeding, however, their inappropriate activation under pathological conditions leads to thrombosis resulting in major cardiovascular diseases such as heart attack and stroke. Read more
 Supervisor: Prof SV Vaiyapuri
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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