We have 32 medicinal chemistry PhD Projects, Programmes & Scholarships

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medicinal chemistry PhD Projects, Programmes & Scholarships

We have 32 medicinal chemistry PhD Projects, Programmes & Scholarships

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P14) Sustainable Synthesis for Medicinal Chemistry in 3-Dimensions: Bioisosteres, PROTAC Linkers, Scaffold Hopping and Unnatural Amino Acids

The O’Brien group has an ongoing interest in exploring sp3-rich scaffolds for use in medicinal chemistry. Read more
 Supervisor: Prof P O'Brien
 13 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Design, Synthesis, and Biological Evaluation of Novel Small-Molecule Therapeutics for Oncology

Applications are invited from high-calibre international candidates for a self-funded PhD project in medicinal chemistry and cancer drug discovery with Dr Ali Raoof. Read more
 Supervisors: Dr AR Raoof, Dr S Butterworth
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Synthesis of Fluorinated Heterocycles (Ref: CM/MK-SF2/2026)

This project will involve synthetic organic chemistry to prepare novel nitrogen heterocyclic compounds based (including pyridones, cinnolines or quinoxalines) using nucleophilic aromatic substitution (SNAr) of fluoroarenes to allow rapid construction of small molecules of interest as drug candidates as antibiotics, anti-cancer agents or against Neglected Tropical Diseases. Read more
 Supervisors: Dr G Weaver, Dr M Kimber
 31 December 2026  PhD Research Project  Self-Funded PhD Students Only
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Computational Design and Study of Peptide-Like Foldamers for Supramolecular and Medicinal Chemistry

These projects are open to students worldwide, but have no funding attached. Therefore, the successful applicant will be expected to fund tuition fees at the relevant level (home or international) and any applicable additional research costs. Read more
 Supervisors: Dr L Trembleau, Prof H Deng
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Development of New Chemical Biology Probes for Medicinal Chemistry Applications

This project will center around the development of novel tool compounds for diseases of societal need, and is collaborative with GSK as an industrial partner. Read more
 Supervisor: Prof C Jamieson
 Year round applications  PhD Research Project  Funded PhD Project (UK Students Only)
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PhD Opportunity in Electrosynthesis for Medicinal and Organic Synthesis

Location. University of Greenwich, Kent, UK. Duration. 3 years, full-time. The Project. We are seeking an ambitious and talented PhD candidate to join the Lam Research Group at the University of Greenwich, working at the forefront of electrosynthesis, sustainable organic synthesis, and reaction innovation. Read more
 Supervisor: Prof K Lam
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Broadening the spectrum of antibacterial drugs to tackle multi-drug resistant Gram-negative pathogens

  Research Group: Astbury Centre for Structural Molecular Biology
Antibiotics make possible the treatment and cure of life-threatening bacterial infections and have added over a decade to average human lifespan. Read more
 Supervisors: Prof A O'Neill, Dr M McPhillie
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Identifying Novel Therapeutics for the Treatment of Alpha-Synucleinopathies: A Chemistry-Biology Approach to Parkinson's Disease

The Clinical Challenge. Parkinson's Disease and Protein Aggregation. Parkinson's disease affects approximately 150,000 people in the UK and accounts for around 8,000 deaths annually. Read more
 Supervisor: Dr J Sellars
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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[School of Natural Sciences PhD Scholarships] Electrosynthetic and Photocatalytic Manipulation of Cyclic Amides toward Novel Stereodefined Heterocycles

The development of next-generation therapeutics demands innovative synthetic methods capable of accessing increasingly complex, three-dimensional molecular architectures with precise control over structure and stereochemistry. Read more
 Supervisors: Dr GEM Crisenza, Dr C Trujillo
 Year round applications  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Dual Ended HDAC-Bcl-2 Inhibitor Therapeutics (DEHBIT): A Continuous Flow Chemistry Approach to Next-Generation Polypharmacological Cancer Therapeutics

Background and Scientific Rationale . Cancer remains one of the most significant global health challenges, characterised by complex, multifactorial disease mechanisms requiring equally sophisticated therapeutic strategies. Read more
 Supervisor: Dr J Sellars
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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PRIMED for Medincinal Chemistry (PRecision, AI Informed, Molecular EDiting)

  Research Group: Rebecca Goss
The PhD focusses on innovative precision molecule editing and diversification. PRIMED combines late stage enzymatic halogenation with synthetic diversification of aryl and alyl halides. Read more
 Supervisor: Prof JM Goss
 Year round applications  PhD Research Project  Funded PhD Project (Students Worldwide)
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Developing Next‑Generation Boron Compounds for BNCT Cancer Therapy

We invite applications for a PhD project focused on the design, synthesis and evaluation of novel boron-rich small molecules for Boron Neutron Capture Therapy (BNCT). Read more
 Supervisors: Dr M Jones, Dr J Coverdale, Prof J Parsons
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Innovative Drug Discovery: First-in-Class Small Molecules for Unmet Medical Needs

This PhD project will develop first-in-class small-molecule therapeutic candidates for diseases with substantial unmet medical need. Read more
 Supervisor: Prof X Lei
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Towards the development of a novel class of broad-spectrum anti-infective drugs

Through exceptionally strong research collaborations at the interface of chemistry, biology, and medicine, we have applied innovative thinking to the field of (Minor Groove Binders) MGBs to develop a novel platform for drug discovery with the potential to treat an impressive range of diseases, including bacterial, fungal, parasitic, and viral infections. Read more
 Supervisor: Dr FS Scott
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigation of the critical roles of platelets at the interface between thrombosis and inflammation in order to develop improved therapeutic strategies for the treatment and/or prevention of cardiovascular/inflammatory diseases

Platelets (small circulating blood cells) are involved in blood clotting to prevent excessive bleeding, however, their inappropriate activation under pathological conditions leads to thrombosis resulting in major cardiovascular diseases such as heart attack and stroke. Read more
 Supervisor: Prof SV Vaiyapuri
 Year round applications  PhD Research Project  Self-Funded PhD Students Only