We have 233 MRC PhD Projects, Programmes & Scholarships

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MRC PhD Projects, Programmes & Scholarships

We have 233 MRC PhD Projects, Programmes & Scholarships

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Exploiting Mitochondrial Genome Editing to Study Leber Hereditary Optic Neuropathy

University of Cambridge
Cambridge Institute for Medical Research
Background. Mutations in mitochondrial DNA (mtDNA) are the most common cause of inherited mitochondrial disease and are increasingly implicated in common age-related conditions including neurodegeneration. Read more
 Supervisor: Prof M Minczuk
 8 December 2026  PhD Research Project  Funded PhD Project (UK Students Only)
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Precision Medicine DLA – Mechanistic interpretation of tissue foundation models: Patient-by-patient endotyping to uncover disease mechanisms in chronic disease and cancer

University of Glasgow
College of Medical, Veterinary & Life Sciences
  Research Group: Institute of Cancer Sciences
Artificial intelligence foundation models are now trained on extensive tissue repositories measuring multiplexed proteins and spatial transcriptomics. Read more
 Supervisors: Dr K yuan, Prof J LeQuesne, Prof RD DasGupta, Dr X Fu
 11 January 2027  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Precision Medicine DLA – Metabolomic signatures of hypertension, diabetes and cardiometabolic multimorbidity in rural and urban Malawi: stratification, inequalities and prediction of incident disease

University of Glasgow
College of Medical, Veterinary & Life Sciences
  Research Group: Institute of Infection, Immunity & Inflammation
Hypertension and diabetes are rising rapidly in sub-Saharan Africa, frequently co-occur, and are often diagnosed late. Yet almost all evidence on the molecular biology of cardiometabolic disease and nearly all metabolomic risk tools come from high-income, European-ancestry populations. Read more
 Supervisors: Dr P Maffia, Dr O Nkoka, Prof M Crampin, Dr P Pellicori
 11 January 2027  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Precision Medicine DLA – Photon-Counting CT Biomarkers for Early Precision Stratification of Coronary Plaque

University of Glasgow
College of Medical, Veterinary & Life Sciences
  Research Group: Institute of Cardiovascular and Medical Sciences
Coronary artery disease remains a leading cause of death, yet current CT angiography chiefly grades luminal stenosis rather than plaque composition, missing many patients with vulnerable but non-obstructive plaque who go on to have heart attacks. Read more
 Supervisors: Dr A Perelli, Dr R Bates, Prof MW Williams, Prof S Padmanabhan
 11 January 2027  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Precision Medicine DLA – Precision Prevention and Management of Adult Dental Caries: Distributional Effectiveness and Cost-Effectiveness Analysis Using Individual Participant Data from Randomised Clinical Trials

University of Glasgow
College of Medical, Veterinary & Life Sciences
  Research Group: Institute of Health and Wellbeing
Dental caries remains one of the most prevalent chronic conditions worldwide and is responsible for substantial healthcare and societal (lost productivity) costs, dental pain, tooth loss and inequalities in oral health. Read more
 Supervisors: Dr B Goulao, Dr J Lewsey, Dr D Boyers
 11 January 2027  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Precision Medicine DLA – Repairing the epithelial barrier in IBD to restore intestinal homeostasis

University of Glasgow
College of Medical, Veterinary & Life Sciences
  Research Group: Institute of Infection, Immunity & Inflammation
Crohn’s disease (CD) is a common form of inflammatory bowel disease. It occurs when the immune system mistakenly attacks normal gut bacteria, damaging the intestine. Read more
 Supervisors: Prof S Milling, Dr M Pineda, Prof K Tokatlidis, Dr UZ Ijaz
 11 January 2027  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Precision Medicine DLA – Anticholinergic burden, heat exposure and health outcomes: a linked-data approach to tackling inequalities

University of Glasgow
College of Medical, Veterinary & Life Sciences
  Research Group: Institute of Health and Wellbeing
Heatwaves are becoming more frequent and intense in Europe, but their health impacts are not shared equally. Many commonly prescribed medicines, including antipsychotics, antidepressants and antihistamines have anticholinergic effects that can reduce sweating and impair the body’s ability to regulate temperature. Read more
 Supervisors: Dr C Niedzwiedz, Dr P Hanlon, Dr J Lewsey, Dr M Sundström
 11 January 2027  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Precision Medicine DLA – Identifying scar-associated macrophages in early Crohn’s disease

University of Glasgow
College of Medical, Veterinary & Life Sciences
  Research Group: Institute of Infection, Immunity & Inflammation
Crohn’s disease, with ulcerative colitis, form the principal inflammatory bowel diseases, which affect 1% of people in Edinburgh and Glasgow. Read more
 Supervisors: Dr G Jones, Dr C Bain, Dr P Ramachandran
 11 January 2027  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Precision Medicine DLA – Genomic and mathematical approaches for the precise targeting of public health interventions to control viral emergence

University of Glasgow
College of Medical, Veterinary & Life Sciences
  Research Group: Institute of Infection, Immunity & Inflammation
Emerging pathogens are an ongoing threat to human health globally. At the start of outbreaks, there is a small amount of available data, as case numbers are low. Read more
 Supervisors: Dr V Hill, Prof D Robertson, Prof A Rambaut
 11 January 2027  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Precision Medicine DLA – Precision Prevention of Kidney Stone Disease: Epidemiology, Health Inequalities, and Incretin-Based Therapies

University of Glasgow
College of Medical, Veterinary & Life Sciences
  Research Group: Institute of Health and Wellbeing
Kidney stone disease (KSD) is common and recurrent, affecting ~10% of the population. It causes substantial morbidity and healthcare utilisation, including emergency hospital admissions and operations. Read more
 Supervisors: Dr KW Wing, Dr C Lovegrove, Dr J Friday
 11 January 2027  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Precision Medicine DLA – Investigating the role and function of top scoring genes identified through a meta-analysis of CML LSC datasets, focusing on RXFP1

University of Glasgow
College of Medical, Veterinary & Life Sciences
  Research Group: Institute of Cancer Sciences
Chronic myeloid leukaemia (CML) is a myeloproliferative disease driven by a translocation between chromosomes 9 and 22 in a haematopoietic stem cell (HSC), resulting in the formation of a leukaemic stem cell (LSC). Read more
 Supervisors: Dr V Helgason, Dr K Roy, Dr S Mariani
 11 January 2027  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Precision Medicine DLA – Predicting and preventing antimicrobial resistance through patient-specific infection ecology

University of Glasgow
College of Medical, Veterinary & Life Sciences
  Research Group: Institute of Biodiversity, Animal Health and Comparative Medicine
In the clinic, antimicrobial treatments are routinely chosen based on an assessment of their immediate efficacy on the most abundant pathogen lineage isolated from an infection. Read more
 Supervisors: Dr L Mancini, Dr J Rudkin, Dr K Oravkova, Dr S Granneman
 11 January 2027  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Precision Medicine DLA – How do tumours heal in response to acute injury and chemotherapy?

University of Glasgow
College of Medical, Veterinary & Life Sciences
  Research Group: Institute of Cancer Sciences
In this PhD project, the prospective student will study how tumours respond to acute injury and chemotherapy, using a novel Drosophila tumour model developed by the Davidson lab that allows live, in vivo confocal imaging of tumour cell death and inflammation. Read more
 Supervisor: Dr A Davidson
 11 January 2027  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Precision Medicine DLA – Divergent structural genomic instability trajectories in mesothelioma: linking tumour evolution to socioeconomic and occupational health inequalities

University of Glasgow
College of Medical, Veterinary & Life Sciences
  Research Group: Institute of Cancer Sciences
Mesothelioma is an asbestos-driven cancer with a median survival of around one year. The UK currently has the world's highest incidence, reflecting historical asbestos utilisation and ongoing environmental exposures. Read more
 Supervisors: Prof K Blyth, Dr T Robertson, Prof C Semple
 11 January 2027  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Precision Medicine DLA – Defining molecular endotypes of respiratory viral disease for precision medicine

University of Glasgow
College of Medical, Veterinary & Life Sciences
  Research Group: Institute of Infection, Immunity & Inflammation
Respiratory viral infections cause highly variable disease, reflecting differences in viral types, infection contexts and the host response. Read more
 Supervisors: Dr A daSilva Filipe, Prof D Robertson, Dr K McLuskey, Prof D Dockrell
 11 January 2027  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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