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PhD Projects, Programmes & Scholarships

We have 3,359 PhD Projects, Programmes & Scholarships

The macromolecular basis of nuclear remodelling in humans

Medical Research Council (Cambridge)

Laboratory of Molecular Biology

Our lab focuses on understanding the processes which lead to a reshaping of the nuclear compartment in health and disease. The nucleus is continuously reshaped by the cytoskeletal filaments that surround it. Read more

Supervisor: Dr M Allegretti

8 December 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

Investigating how water-rock interactions influence geothermal reservoir sustainability using experiments and geochemical modelling

Newcastle University

School of Natural and Environmental Sciences

Award summary. 100% home fees covered, and a minimum tax-free annual living allowance of £21,805 (2026/27 UKRI rate). An additional allowance will be provided to contribute towards consumables, equipment, and travel related to the project. Read more

Supervisor: Dr S Acikalin

2 October 2026 PhD Research Project Funded PhD Project (UK Students Only)

Structures and mechanisms of the human replisome

Medical Research Council (Cambridge)

Laboratory of Molecular Biology

Accurate genome duplication is essential for all forms of life. Read more

Supervisor: Dr J Yeeles

8 December 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

Closing the loops: Unleashing the poteintial mTORC2.

Medical Research Council (Cambridge)

Laboratory of Molecular Biology

mTORC2 can integrate multiple activating influences to positively influence anabolism, survival and cytoskeletal remodelling. We have characterised a positive feedback loop between mTORC2 and AKT and have shown that mTORC2 has a great potential for activation that has been overlooked in previous work. Read more

Supervisor: Dr R Williams

8 December 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

Non-protein ubiquitylation in infection and physiology

Medical Research Council (Cambridge)

Laboratory of Molecular Biology

Ubiquitylation is essential for eukaryotic life. Until recently, proteins were the only substrates known to be modified with ubiquitin. Read more

Supervisor: Dr F Randow

8 December 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

Funded project GW4 BioMed3 MRC DTP - Gatekeepers of GPCR Signalling: Degradation Pathways in Health and Diseas

University of Bristol

School of Biochemistry and Biomedical Sciences

G protein-coupled receptors (GPCRs) are the largest family of cellsurface signalling proteins and mediate communication between cells throughout the body and brain. Read more

Supervisors: Dr A Grieve, Prof I Collinson

21 October 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

The life cycle of ecDNA

Medical Research Council (Cambridge)

Laboratory of Molecular Biology

A major focus of the lab is understanding the links between replication and mutagenesis (1‑4). Extrachromosomal DNA (ecDNA) circles are present in a substantial proportion of cancers and frequently harbour oncogenes that drive tumour proliferation (5). Read more

Supervisor: Dr J Sale

8 December 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

TRIM21 degradation of viruses and aggregates

Medical Research Council (Cambridge)

Laboratory of Molecular Biology

TRIM21 is the cytosolic E3 ligase and antibody receptor responsible for intracellular antibody immunity. Unlike other ubiquitin ligases, TRIM21 doesn’t have a defined substrate but is directed towards its targets by antibodies. Read more

Supervisor: Dr L James

8 December 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

Investigating cellular mechanisms of tissue homeostatis and fibrosis using omics approaches

University of Southampton

School of Biological Sciences

Understanding how cells maintain tissue health or trigger irreversible decline is a frontier challenge in biomedical science. Using lung fibrosis as a primary disease model, this project investigates the core molecular networks controlling cellular fate, tissue regeneration, and scarring. Read more

Supervisors: Dr K N Natarajan, Dr M Jones

18 October 2026 PhD Research Project Funded PhD Project (UK Students Only)

Replicating RNA with RNA

Medical Research Council (Cambridge)

Laboratory of Molecular Biology

A critical event in the origin of life is thought to have been the emergence of an RNA molecule capable of self-replication as well as mutation, and hence evolution towards ever more efficient replication. Read more

Supervisor: Dr P Holliger

8 December 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

Circuit basis of learning and action-selection

Medical Research Council (Cambridge)

Laboratory of Molecular Biology

The overall goal of our research is to discover the circuit implementation of learning and action selection. Read more

Supervisor: Dr M Zlatic

8 December 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

Transforming Thoughts into Actions

Medical Research Council (Cambridge)

Laboratory of Molecular Biology

How does the brain transform what we perceive into what we do? Even a simple action, such as stopping at a red light and moving again when it turns green, requires the brain to select relevant sensory information, form an intention, prepare an appropriate movement and execute it at the right moment. Read more

Supervisor: Dr M Tripodi

8 December 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

Neuropeptide networks in worms and octopus

Medical Research Council (Cambridge)

Laboratory of Molecular Biology

In recent years, great efforts have been made to map the synaptic wiring diagrams of simple and complex nervous systems. However, chemical synapses, the connections used in most connectomics research, represent only one type of functionally important signalling between neurons. Read more

Supervisor: Dr W Schafer

8 December 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

Pathological protein assembly in neurodegenerative diseases

Medical Research Council (Cambridge)

Laboratory of Molecular Biology

Neurodegenerative diseases are one of the greatest health challenges facing our society. This large group of diseases is characterised by the pathological assembly of specific proteins into amyloid filaments in the central nervous system. Read more

Supervisor: Dr B Falcon

8 December 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

Connectomics across sexes, species and states

Medical Research Council (Cambridge)

Laboratory of Molecular Biology

Neuroscience in the fly and beyond is being transformed by the availability of connectomes, synaptic resolution wiring diagrams. We have played leading roles in two large collaborations that have recently generated and analysed separate (female) brain and (male) nerve cord connectomes for the fly. Read more

Supervisor: Dr G Jefferis

8 December 2026 PhD Research Project Competition Funded PhD Project (Students Worldwide)

Unitary quantum gravity and the fate of black holes

University of Sheffield

School of Mathematical and Physical Sciences

Research Group: Applied Mathematics

Black holes have now been observed in detail via astrophysical observations, detections of gravitational waves and pictures of the event horizon. Read more

Supervisor: Dr S Gielen

Year round applications PhD Research Project Self-Funded PhD Students Only

Synchronization of turbulent channel flow

University of Sheffield

School of Mathematical and Physical Sciences

Research Group: Applied Mathematics

Chaos may seem like complete disorder, but even chaotic systems can sometimes fall into step — a phenomenon called chaos synchronisation. Read more

Supervisors: Dr Y Li, Dr A P Willis

Year round applications PhD Research Project Self-Funded PhD Students Only

Stereoselective Synthesis of Atropisomers. Application to Natural Products and Drug-like Intermediates

University of Sheffield

School of Mathematical and Physical Sciences

Research Group: Chemical Biology

Atropisomers represent an important class of chiral molecules whereby stereoisomerism is determined by ease of rotation about a single bond. Read more

Supervisor: Prof JPA Harrity

Year round applications PhD Research Project Self-Funded PhD Students Only

Spin and superradiance in General Relativity

University of Sheffield

School of Mathematical and Physical Sciences

Research Group: Applied Mathematics

In General Relativity, bodies in freefall follow geodesics in spacetime. For example, the Earth follows a geodesic in the spacetime of the Sun, to a good approximation. Read more

Supervisor: Dr S Dolan

Year round applications PhD Research Project Self-Funded PhD Students Only

Spacetime emergence and cosmological dynamics in group field theory

University of Sheffield

School of Mathematical and Physical Sciences

Research Group: Applied Mathematics

Many theories of quantum gravity agree that the spacetime geometry of Einstein’s general relativity needs to be replaced by a different underlying structure. Read more

Supervisor: Dr S Gielen

Year round applications PhD Research Project Self-Funded PhD Students Only

Silicon Sensor Particle Detectors for the Upgrade of the ATLAS Experiment and other Detectors at the CERN LHC

University of Sheffield

School of Mathematical and Physical Sciences

Research Group: Particle Physics and Particle Astrophysics

A position is open for an enthusiastic particle physics PhD student to conduct research in developing silicon sensor technologies in use at the energy frontier at the ATLAS experiment. Read more

Supervisors: Dr T Vickey, Dr K Lohwasser

Year round applications PhD Research Project Self-Funded PhD Students Only

Searching for Triple Higgs Boson Production with the ATLAS Experiment at the CERN LHC

University of Sheffield

School of Mathematical and Physical Sciences

Research Group: Particle Physics and Particle Astrophysics

It's widely believed that the Standard Model (SM) of particle physics is an incomplete theory. The 125 GeV Higgs boson, discovered by the CERN ATLAS and CMS Experiments, is a crucial probe for physics Beyond the Standard Model (BSM) of particle physics. Read more

Supervisors: Dr T Vickey, Dr C Anastopoulos

Year round applications PhD Research Project Self-Funded PhD Students Only

Searching for Sterile Neutrinos and other Beyond the Standard Model phenomena with SBND

University of Sheffield

School of Mathematical and Physical Sciences

Research Group: Particle Physics and Particle Astrophysics

The SBND (Short-Baseline Near Detector) experiment is part of the multi-detector Short Baseline Neutrino (SBN) programme located along the Booster Neutrino Beamline at Fermilab, USA. Read more

Supervisors: Dr R S Jones, Prof E Daw

Year round applications PhD Research Project Self-Funded PhD Students Only

Physics-Informed Data Assimilation in Wall-Bounded Turbulence

University of Sheffield

School of Mathematical and Physical Sciences

Research Group: Applied Mathematics

Data assimilation combines physical models with experimental or numerical data to produce dynamically consistent flow reconstructions. Read more

Supervisors: Dr Y Li, Dr A P Willis

Year round applications PhD Research Project Self-Funded PhD Students Only

Novel materials and catalytic processes for the clean-up of organic pollutants in water

University of Sheffield

School of Mathematical and Physical Sciences

Research Group: Materials Chemistry

Clean water is one of the most pressing global challenges of our time, with major implications for health, sustainability, and industry. Read more

Supervisor: Dr M Conte

Year round applications PhD Research Project Self-Funded PhD Students Only

Asymmetric Synthesis of Boronic Ester Heterocycles

University of Sheffield

School of Mathematical and Physical Sciences

Research Group: Chemical Biology

Boron containing molecules are of high value, as they have many applications in chemical synthesis, materials science, and catalysis. Read more

Supervisor: Dr BM Partridge

Year round applications PhD Research Project Self-Funded PhD Students Only

Backreaction of quantum fields on black hole space-times

University of Sheffield

School of Mathematical and Physical Sciences

Research Group: Applied Mathematics

In classical general relativity, Einstein’s equations involve the curvature of space-time on the left-hand-side, and the stress-energy tensor of matter on the right-hand-side. Read more

Supervisor: Prof E Winstanley

Year round applications PhD Research Project Self-Funded PhD Students Only

Bayesian Index Tracking: optimisation by sampling

University of Sheffield

School of Mathematical and Physical Sciences

Research Group: Mathematical and Statistical Modelling

Index trackers (ETFs, index funds, index mutual funds) aim to replicate the return of a reference equity index while keeping implementation frictions---notably turnover and trading costs---under control. Read more

Supervisors: Dr K Triantafyllopoulos, Dr D Roxanas

Year round applications PhD Research Project Self-Funded PhD Students Only

Beyond ΛCDM: Testing New Physics with the CMB and Large-Scale Structure

University of Sheffield

School of Mathematical and Physical Sciences

Research Group: Applied Mathematics

Precision measurements of the Cosmic Microwave Background (CMB) from Planck have established ΛCDM as the standard cosmological model. Read more

Supervisor: Dr E Divalentino

Year round applications PhD Research Project Self-Funded PhD Students Only

Black hole perturbation theory for gravitational-wave astronomy

University of Sheffield

School of Mathematical and Physical Sciences

Research Group: Applied Mathematics

Pairs of black holes generate distinctive 'chirp' signals as they coalesce. These signals have been successfully detected at gravitational-wave observatories since 2015. Read more

Supervisor: Dr S Dolan

Year round applications PhD Research Project Self-Funded PhD Students Only

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