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PhD Projects, Programmes & Scholarships

We have 5,813 PhD Projects, Programmes & Scholarships

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Uncovering the molecular mechanisms of PIKfyve complex regulation

How cells control how they process intracellular compartments is key to maintain normal function and defective trafficking is often the main cause of diseases such as neurodegeneration and cancer. Read more
 Supervisors: Prof J King, Dr D Humphreys
 6 January 2027  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Unravelling membrane-supported proton diffusion in synaptic vesicle bioenergetics

Brain function relies on fast, precise communication between neurons, mediated by the release of chemical messengers called neurotransmitters. Read more
 Supervisors: Prof N Amdursky, Dr M De Felice
 6 January 2027  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Multi-wavelength Raman spectroscopy for non-invasive differentiation of ageing and metabolic risk signatures in blood plasma and saliva

Project Description. Could a simple saliva sample one day replace a blood test for health screening? This PhD project uses a laser-based technique called Raman spectroscopy, which reveals a chemical "fingerprint" of a biological sample without needles, chemical labels or lengthy lab processing. Read more
 Supervisors: Dr R Mughal, Dr A R Pallipurath, Dr JS Stephenson, Dr HV Viswhambharan, Dr K Riches-Suman
 6 January 2027  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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RNA-binding protein secretion by aging neurons: the key to spreading proteotoxicity?

This PhD project investigates the fundamental cell biology of neuronal aging, focusing on how cellular senescence rewires proteostasis and non-cell-autonomous communication in the central nervous system. Read more
 Supervisors: Dr T Shelkovnikova, Dr J Cooper-Knock, Prof JR Boyne, Dr Rahul S Samant
 6 January 2027  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Bioactive Edible Films as Delivery Systems for Sea Buckthorn Phenolics: Gastrointestinal Fate, Microbial Biotransformation and Gut Microbiome Modulation

Project Description. Sea buckthorn (Hippophae rhamnoides L.) is rich in phenolic compounds with antioxidant and antimicrobial activity, but their biological effects depend strongly on how they are released, transformed and metabolised during digestion. Read more
 Supervisors: Dr A Angelis-Dimakis, Dr MD Dimopoulou, Dr E Karunakaran
 6 January 2027  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Should I stay or should I go? How do immune cells know when to leave sites of tissue damage?

Cancer, neurodegeneration and COPD are all associated with chronic inflammation, leading to tissue damage and disease. However, failures of immune cells to respond or remain at injuries leaves patients exposed to infection and compromises regeneration. Read more
 Supervisors: Dr I Evans, Dr P Elks, Prof S Johnston
 6 January 2027  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Development of a quantitative multi-parametric in ovo bioscreening platform for comparative evaluation of engineered viral biotherapeutics in complex tissue microenvironments.

Project Description. Engineered viral biotherapeutics, including gene-delivery vectors and emerging cancer therapies, are transforming biotechnology and medicine. Read more
 Supervisors: Dr S Allison, Dr N McCaul, Prof E Blair
 6 January 2027  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Coordination cages for sensing and catalytic decomposition of chemical warfare agents

Supervisors. Dr Richard Knighton R.C.Knighton@soton.ac.uk. Dr Adrian Nightingale A.Nightingale@soton.ac.uk. Project title. Coordination cages for sensing and catalytic decomposition of chemical warfare agents. Read more
 Supervisor: Dr RK Knighton
 18 December 2026  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Nanophotonic environmental sensor

Clean water is an essential need that we take for granted. Nevertheless, many people in the developing world only have access to potentially contaminated water yet they have no simple and reliable way of testing it. Read more
 Supervisor: Prof T Krauss
 31 January 2027  PhD Research Project  Funded PhD Project (UK Students Only)
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DNA demethylation during seed development and germination

Are you an ambitious undergraduate eager to tackle fundamental questions in plant biology and epigenetics? Join our cutting-edge research groups to investigate how dynamic DNA demethylation shapes plant reproduction, seed development, and germination. Read more
 Supervisors: Dr L Smith, Prof J Ton, Dr M Collins
 6 January 2027  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Innovative DPhil (PhD) Programme in Zero-Carbon Energy at Oxford University

Innovative DPhil (PhD) Programme in Zero-Carbon Energy at Oxford University. Thinking about a PhD researching the energy transition? We’ve got you covered. Read more
 Supervisor: Prof PS Shearing
 2 December 2026  PhD Research Project  Self-Funded PhD Students Only
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Control and inhibition of virus replication

The Tuplin group explores how RNA viruses regulate replication and translation of their genomes through dynamic interactions between structured viral RNA, host and viral proteins and host-cell non-coding RNAs (including siRNAs, lncRNAs, and circRNAs). Read more
 Supervisor: Dr A.K Tuplin
 31 May 2027  PhD Research Project  Self-Funded PhD Students Only
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Intelligent Battery Management for Grid-Scale Energy Storage Systems

The increasing integration of renewable energy and the growing demand for flexible, reliable electricity networks are driving the development of advanced battery energy storage systems. Read more
 Supervisor: Dr E Hosseinzadeh
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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A modular adhiron-VLP platform for targeted molecular delivery

Project Description. A central challenge in targeted delivery is the lack of a truly modular platform in which the targeting molecule, the display scaffold and the payload can each be varied independently. Read more
 Supervisors: Dr N McCaul, Dr S Allison, Prof D Tomlinson
 6 January 2027  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Laser focused on drought stress - using biosensors to decipher crop stomatal responses to drought

We welcome applicants for a plant science competitively funded PhD studentship in Jim Rowe, Julie Gray, and Pallavi Singh’s groups. Read more
 Supervisors: Dr J Rowe, Prof J Gray, Dr PS Singh
 6 January 2027  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Establishing structure-function relationships and economic and environmental merits of arabinoxylan materials from integrated biorefineries

Project Description. Arabinoxylans (AX) are a class of novel and functional hemicellulose fibre materials well matched to co-production with bioethanol in an integrated biorefinery, with potential to become a multi-billion pound market. Read more
 Supervisors: Prof G Campbell, Dr A Angelis-Dimakis, Dr L Gomez
 6 January 2027  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Development of a High-Power Nuclear Electric Propulsion System for Rapid Space Transportation

Supervisors. Prof Minkwan Kim m.k.kim@soton.ac.uk. Prof Matthew Middleton M.J.Middleton@soton.ac.uk. Project title. Development of a High-Power Nuclear Electric Propulsion System for Rapid Space Transportation. Read more
 Supervisor: Prof M K Kim
 18 December 2026  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Quantum and many-body effects in quantum thermodynamic devices

Fabrication and operation of devices for quantum technologies will be subject to limits imposed by thermodynamics. However, these devices’ components are often so small that can be described by a relatively small number of degrees of freedom, so that conventional thermodynamics cannot describe them properly. Read more
 Supervisor: Prof ID D'Amico
 30 September 2027  PhD Research Project  Self-Funded PhD Students Only
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Understanding how keratin filaments enable cells to withstand mechanical forces

Tissues within the body are frequently exposed to mechanical forces such as stretch and compression. In proliferating epithelial tissue, cells need to be able to protect their nucleus from physical damage during tissue deformations. Read more
 Supervisors: Dr H Matthews, Prof C Toseland, Dr R Peters
 6 January 2027  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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A materials science approach to the design of peptide formulations for parenteral administration

Project Description. Biopharmaceuticals, also known as biologics, are an ever-growing segment of the pharmaceutical industry. The vast majority of these large molecules are administered through injection in the form of aqueous solutions. Read more
 Supervisors: Prof L Waters, Dr JB Booth, Prof D B Brockwell
 6 January 2027  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Portable microfluidic cell function diagnostics for measuring health status.

Supervisors. Associate Professor Jonathan West J.J.West@soton.ac.uk. Associate Professor Al Edwards A.D.Edwards@soton.ac.uk. Dr Ernesto Elias Vidal Rosas E.E.Vidal-Rosas@soton.ac.uk. Read more
 Supervisor: Dr J West
 18 December 2026  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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EPSRC CDT in Inorganic Materials for Advanced Manufacturing (IMAT) - fully funded studentships

The Inorganic Materials for Advanced Manufacturing Centre for Doctoral Training (IMAT CDT) is an EPSRC-funded multi-disciplinary programme. Read more
 Funded PhD Programme (Students Worldwide)  EPSRC Centre for Doctoral Training
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Mechanisms and exploitation of phage host hijacking

By the year 2050, it is estimated that antimicrobial resistance will generate 10 million excess deaths per year. There is a major threat from the so-called ESKAPE pathogens, including vancomycin-resistant enterococci (VRE), due to failing of front-line drugs. Read more
 Supervisors: Prof P A Bullough, Dr Jason Wilson
 6 January 2027  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Distributed in-situ phytoplankton monitoring instruments for the study of estuarine plankton dynamics

Project description. River estuaries are host to critical biogeochemical processes, which play a key role in plankton biodiversity and, by extension, the coastal food web. Read more
 Supervisors: Dr J Beuchert, Dr J Lawson, Dr E García-Martin, Dr NP Pham
 7 January 2027  PhD Research Project  Funded PhD Project (Students Worldwide)
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Who Pulls the Strings? Unravelling the Non-Coding Regulators of Cellular Dormancy in Breast Cancer

Why do some breast cancer cells lie dormant for years before suddenly reawakening to cause incurable metastatic relapse? This project investigates one of the most poorly understood aspects of cancer biology. Read more
 Supervisors: Dr Lewis Quayle, Prof P Ottewell, Prof C Toseland, Prof D Lambert
 6 January 2027  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Development of economical, sustainable and scalable fluorination technologies

Background. Fluorinated compounds are vital to modern society they are ubiquitous across the pharmaceutical and materials sectors due to the interesting chemical and physical properties that incorporation of fluorine atoms can impart. Read more
 Supervisor: Dr WB Brittain
 Year round applications  PhD Research Project  Funded PhD Project (UK Students Only)
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The integrated stress response (ATF4) in ageing

Societal ageing presents a major challenge to healthcare systems. Geroscience offers a solution, proposing that targeting the biological drivers of ageing can simultaneously delay multiple age-related diseases. Read more
 Supervisors: Dr M J P Simons, Dr A Lin, Prof J Ton
 6 January 2027  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Designing de novo protein biomaterials for solar energy capture and quantum sensing

Photosynthesis is one of nature’s most successful processes, efficiently capturing sunlight and converting it into useful energy. Read more
 Supervisors: Prof J Clark, Dr A Hitchcock
 6 January 2027  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Modelling the Mouth: Enamel Remineralisation Strategies for Oral Health

Project Description. Haleon is committed to creating a diverse, equitable and inclusive workplace where all colleagues are treated with dignity and respect and have the opportunity to fulfil their potential. Read more
 Supervisors: Dr H Chappell, Dr J Smith
 6 January 2027  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Nuclear Myosin VI supports DNA repair and is a potential therapeutic target

This fully funded PhD project offers the opportunity to investigate how the molecular motor myosin VI (MVI) contributes to DNA repair processes and cancer therapy. Read more
 Supervisors: Prof C Toseland, Dr M Newton, Prof K Pors
 6 January 2027  PhD Research Project  Competition Funded PhD Project (Students Worldwide)