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We have 23 Microbiology (antibiotic resistance) PhD Research Projects PhD Projects, Programmes & Scholarships

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Microbiology (antibiotic resistance) PhD Research Projects PhD Projects, Programmes & Scholarships

We have 23 Microbiology (antibiotic resistance) PhD Research Projects PhD Projects, Programmes & Scholarships

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Dissecting the molecular mechanisms of antibiotic resistance in bacterial pathogens

  Research Group: School of Molecular and Cellular Biology
Antibiotics make possible the treatment and cure of life-threatening bacterial infections. Since their introduction in the middle years of the 20th Century, they have added ~10 years to the human lifespan, and have become a cornerstone of modern medicine. Read more
 Supervisor: Prof A O'Neill
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The role of Efflux in Antibiotic Resistance of Clinically Relevant Pathogens

Antibiotics underpin all of modern medicine; they are used to treat bacterial infections, and to prevent infections after surgery and in patients with a suppressed immune system such as those undergoing cancer chemotherapy or organ transplantation. Read more
 Supervisor: Prof J Blair
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Molecular characterization of suicidal phage-resistance mechanisms in bacteria

Importance. The proliferation of antibiotic resistance (AMR) through horizontal-gene-transfer (HGT) is a formidable health challenge, accounting for 700,000 deaths annually1. Read more
 Supervisors: Dr A Koyamangalath Vadakkepat , Dr M Clokie
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Bioinformatics analyses of microbial communities and their genetic contents to understand the transmission dynamics and selection of antimicrobial resistance

Project Overview. Antimicrobial Resistance (AMR) is one of the topics that we cannot ignore. Bacterial infections unsuccessfully treated due to AMR claim at least 700 000 lives per year worldwide and are projected to be associated with the deaths of 10 million people per year by 2050. Read more
 Supervisor: Dr S Gweon
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Revolutionising antimicrobial susceptibility testing to optimise treatment of bacterial infection and overcome AMR

  Research Group: School of Molecular and Cellular Biology
Antimicrobial susceptibility testing (AST) is an essential component of the diagnostic workflow in the clinical microbiology laboratory, since it is able to define which antibiotics have the potential to treat bacterial infection in a given patient. Read more
 Supervisor: Prof A O'Neill
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Developing adjuvants to improve the antibacterial efficacy of fusidic acid: a novel approach to Antimicrobial Resistance?

Background. The antibiotic fusidic acid (FA) blocks bacterial protein synthesis by interacting with Elongation-factor G (EF-G). Resistance to FA is caused by FusB, which interacts with EF-G, altering its motion. Read more
 Supervisors: Dr K Simmons, Dr M McPhillie, Dr J.H. Tomlinson
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Turning bacterial metabolism against antimicrobial resistance

  Research Group: Pletzer lab
Background. Antibiotic-resistant infections are becoming increasingly difficult to treat, particularly those caused by Gram-negative bacteria such as Pseudomonas aeruginosa. Read more
 Supervisor: Dr D Pletzer
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Revolutionising Infection Diagnosis Through Targeted Radiometal Imaging

Please read the Funding note before contacting/applying. Background of the Project. People with conditions like heart disease, diabetes, cancer, organ transplants, or immunodeficiencies face higher risks of infection, complications, and death. Read more
 Supervisor: Dr V Abbate
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Investigating pathogenicity in zoonotic Streptococcus suis

This project offers an exciting opportunity to join a large European consortia and make a tangible impact on a global animal and human health issue. Read more
 Supervisor: Dr L Weinert
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Identification of novel mechanisms of Pseudomonas aeruginosa carbapenem resistance using adaptive laboratory evolution studies.

Pseudomonas aeruginosa was designated a “critical priority pathogen” by the WHO reflecting its ubiquity in the built environment, arsenal of virulence factors, and resistance to multiple antibiotics. Read more
 Supervisor: Dr C Walker
 1 July 2026  PhD Research Project  Funded PhD Project (Students Worldwide)
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The consequences of influenza a virus infection on macrophage host defence functions against bacterial infection

Uncovering How Influenza Turns Bacterial Infections Deadly. Why do influenza pandemics claim so many lives? The answer often isn’t the virus alone, but the lethal synergy between Influenza A Virus (IAV) and secondary bacterial pneumonia. Read more
 Supervisors: Dr H Marriott, Dr J Cole
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Fully Funded PhD Studentship in Molecular Microbiology, Bacterial Metabolism and Antimicrobial Resistance

Applications are invited from suitably qualified candidates for a full-time funded PhD scholarship starting in September/October 2026. Read more
 Supervisor: Dr MS Zeden
 7 July 2026  PhD Research Project  Funded PhD Project (Students Worldwide)
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Develop Cutting-Edge Peptide Therapies to Fight Antimicrobial Resistance in Eye Infections

The cornea, a dome-shaped, transparent tissue at the front of the eye, is crucial for vision. Corneal infections, such as bacterial keratitis (BK), are among the leading causes of unilateral blindness worldwide. Read more
 Supervisors: Dr I Mohammed, Prof A Jones
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Accelerating the clinical introduction of novel antibiotic combinations effective against Gram-negative pathogens

Strathclyde Minor Groove Binders (S-MGB) lead compounds have in vivo activity (MIC 0.2 µg/mL) against Gram-positive bacteria.[1-5] In 2015 our commercial partner, MGB Biopharma, completed the successful Phase I Clinical Trial (NCT02518607) of our lead candidate MGB-BP-3 for the treatment of Clostridium difficile infections. Read more
 Supervisor: Dr FS Scott
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Engineering Nitric Oxide Delivery Platforms for the Treatment of Multidrug-Resistant Infections

This project develops nitric-oxide-releasing polymer platforms to tackle drug-resistant infections. The student will design electrospun and 3D-printed materials that deliver controlled NO doses directly to infection sites and test their antimicrobial performance against clinically relevant pathogens. Read more
 Supervisors: Prof RA D'Sa, Dr J Hanson
 Year round applications  PhD Research Project  Self-Funded PhD Students Only

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