We have 233 MRC PhD Projects, Programmes & Scholarships

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MRC PhD Projects, Programmes & Scholarships

We have 233 MRC PhD Projects, Programmes & Scholarships

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MRC NW-DMS DLA programme: From variant to phenotype: decoding calmodulin dysfunction in cardiac arrhythmia

How can a change in a single protein disrupt the electrical rhythm of the heart and cause life-threatening arrhythmia?. Calmodulin (CaM) is a highly conserved calcium sensing protein that controls key ion channels responsible for cardiac electrical activity and calcium homeostasis. Read more
 Supervisors: Dr N Helassa, Dr R Rainbow
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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MRC NW-DMS DLA programme: How pollution drives brain ageing: understanding its contribution to neurodegenerative pathologies

Diseases like Alzheimer’s, Parkinson’s, and Amyotrophic Lateral Sclerosis are devastating conditions that cause our brain cells to progressively decay. Read more
 Supervisors: Dr N Sanchez-Soriano, Prof H Ashe, Prof S Cruickshank
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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MRC NW-DMS DLA programme: State-selective dependence on SMOC-regulated extracellular signalling in hepatocellular carcinoma

How do liver tumours become dependent on their extracellular environment?. Hepatocellular carcinoma (HCC) is the most common primary liver cancer and a leading cause of cancer death worldwide. Read more
 Supervisors: Dr MM Merino, Prof D Palmer
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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MRC NW-DMS DLA programme: Closing the loop: an AI guided approach to prioritise competence experimentation of emerging arbovirus risk

Mosquitoes and the viruses they carry are on the move. Climate change, land use change and global trade are expanding the ranges of both, bringing vectors and viruses into contact in places that have never had to consider them before. Read more
 Supervisors: Dr M Blagrove, Dr M Wardeh, Dr J Pilgrim
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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MRC NW-DMS DLA programme: Restoring Anti Tumour Immunity by Disrupting Myeloid Driven Immunosuppressive Pathways in Cholangiocarcinoma

Cholangiocarcinoma (CCA) is an aggressive cancer of the bile ducts with a survival rate below 10% over five years. This project focuses on understanding why immune checkpoint blockade therapies, such as durvalumab, have limited success in treating CCA. Read more
 Supervisors: Dr L Randle, Prof N Liptrott, Mr HM Malik
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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MRC NW-DMS DLA programme: Endosomal Trafficking of Dopamine Receptors: Mechanisms, Health, and Disease

Summary. Dysregulation of dopamine receptor trafficking and expression is increasingly recognised as a fundamental contributor to major neurological and neuropsychiatric disorders, including Parkinson’s disease, schizophrenia, addiction and ADHD. Read more
 Supervisors: Dr K McMillan, Prof M Clague, Prof P McCormick
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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MRC NW-DMS DLA programme: Antibiotic taxis during host infection and antibiotic treatment

Background. Pseudomonas aeruginosa is a globally significant “priority” bacterial pathogen (WHO) that causes biofilm-associated, antibiotic-resistant infections. Read more
 Supervisors: Dr J Wheeler, Dr S.K. Khandaker, Dr RT Tank
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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MRC NW-DMS DLA programme: A digital portal incorporating patient-reported outcome measures to improve the equity and effectiveness of outpatient epilepsy care

How can digital tools make specialist epilepsy care fairer, more efficient, and better matched to what matters to patients?. Read more
 Supervisors: Dr J Mitchell, Dr A Noble, Prof T Marson
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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MRC NW-DMS DLA programme: Synthetic Teixobactins for Drug-Resistant Pneumonia Caused by S. pneumoniae and S. aureus

Pneumonia remains a major global cause of death, and antimicrobial resistance is making serious bacterial infections increasingly difficult to treat. Read more
 Supervisors: Dr I Singh, Dr CJ Harding, Dr D Wootton, Dr I Pritchard
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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MRC NW-DMS DLA programme: Longitudinal Ultrasound AI for Identifying High-Risk Fetal Growth Trajectories

Ultrasound is routinely used to monitor fetal growth throughout pregnancy. Clinical concern is usually greatest when a fetus becomes very small, but a more difficult problem occurs when a fetus remains above conventional thresholds while its growth gradually slows across repeated scans. Read more
 Supervisors: Dr HZ Zhao, Dr A Sharp
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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MRC NW-DMS DLA programme: Defining the role of Complement glycosylation during Neisseria gonorrhoeae infection

The Project. Understanding how N.gonorrhoeae exploits complement. Gonorrhoea, caused by Neisseria gonorrhoeae, is a major global health challenge, with more than 80 million infections occurring annually. Read more
 Supervisors: Dr H Lavender, Dr A Chetwynd
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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MRC NW-DMS DLA programme: Automated discovery of inhibitors targeting DNA gyrase to combat antimicrobial resistance

Background and research gap. DNA gyrase is an essential bacterial enzyme that maintains homeostatic control of DNA supercoiling and the target of successful antibacterial compounds. Read more
 Supervisors: Dr HSA Saqib Ali, Prof P O'Neill, Dr G Nixon
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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MRC NW-DMS DLA programme: A novel mechanism linking DNA damage response signalling to neuronal cytoskeletal dysfunction in neurodegeneration

Neurons in the brain communicate through highly interconnected signalling networks that control how we think, move and respond to our environment. Read more
 Supervisors: Dr DB Byrne, Dr N Sanchez-Soriano, Dr K McMillan
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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MRC NW-DMS DLA programme: Towards Mitigating Severe Neurotoxicity in T-cell Immunotherapy

Are you ready to tackle one of the most pressing safety challenges in immuno-oncology?. This NW-DMS CASE PhD studentship offers a translational project at the interface of neuroscience, immunology and drug safety. Read more
 Supervisors: Dr D Dickens, Prof M Pirmohamed, Prof A Dinkova-Kostova
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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MRC NW-DMS DLA programme: In ovo organoid xenografts to accelerate gastric cancer drug and biomarker development

We are looking for a motivated, curious, and ambitious student to join a dynamic research team focused on transforming how we understand and treat gastric cancer. Read more
 Supervisors: Dr C Duckworth, Prof M Pritchard, Prof LG Yu
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)