We have 233 MRC PhD Projects, Programmes & Scholarships

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MRC PhD Projects, Programmes & Scholarships

We have 233 MRC PhD Projects, Programmes & Scholarships

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(MRC NW-DMS) The effects of female reproductive cycles on lung inflammation

The University of Manchester
Division of Integrative Physiology
Summary of research topic. Women spend 25% more of their life in poorer health than men. Inflammation in the lung affects women disproportionately, yet women are under-represented in research, clinical trials and current treatment strategies are not stratified by sex. Read more
 Supervisors: Dr E Mann, Dr L Pearmain, Dr J Grainger
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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(MRC NW-DMS) Resolving enhancer dynamics underlying cell fate decisions during early embryogenesis

The University of Manchester
Division of Developmental Biology and Medicine
  Research Group: Division of Developmental Biology and Medicine
How do embryonic cells choose who they will become? This project tackles this fundamental question in the Neural Plate Border (NPB), a transient embryonic territory where multipotent cells are directed towards Neural Crest (NC) or sensory placode fates, which respectively give rise to peripheral neurons/glia and cranial sensory organs. Read more
 Supervisors: Dr RW Williams, Prof N Bobola, Dr R Das
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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(MRC NW-DMS) Artificial Intelligence versus standard Genome-Wide Association Studies to identify molecular pathways in autoimmune diseases for precision medicine.

The University of Manchester
Division of Musculoskeletal and Dermatological Sciences
Background. Genome-Wide Association Studies (GWAS) were successful in identifying 100s of genetic variants associated with autoimmune disease susceptibility, however, their relevance across ethnicities and their use in clinical medicine in general is limited. Read more
 Supervisors: Dr S Viatte, Dr H Guo, Dr J Bowes, Dr J Lamb, Prof S Bulfone-Paus
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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(MRC NW-DMS) Radiation remodelling of cardiac muscle to suppress arrhythmias – establishing a novel therapy for lamin heart disease

The University of Manchester
Division of Cardiovascular Sciences
  Research Group: Division of Cardiovascular Sciences
Lamin heart disease (LHD) is a devastating genetic condition of the nuclear envelope causing cardiac contractile dysfunction and lethal heart rhythms (arrhythmias). Read more
 Supervisors: Dr D.H. Hutcings, Prof A Trafford, Prof K Williams
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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(MRC NW-DMS) Bioengineering patient-derived retinal models to investigate tissue interaction mechanisms in albinism

The University of Manchester
Division of Developmental Biology and Medicine
  Research Group: Division of Developmental Biology and Medicine
Albinism is an inherited condition that affects pigmentation and can disrupt how the eye develops before birth. It is an important cause of childhood visual impairment. Read more
 Supervisors: Dr Cerys Manning, Dr PS Sergouniotis , Dr M Domingos
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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(MRC NW-DMS CASE) Investigating serum protein biomarkers of breast cancer risk associated with high mammographic density and high-risk mammographic patterns

The University of Manchester
Division of Cancer Sciences
Mammographic density is one of the strongest predictors of breast cancer risk, yet little is known about the biological mechanisms linking dense breast tissue to tumour development. Read more
 Supervisors: Dr B Simoes, Dr SH Howell, Prof R Clarke, Dr J Swift, Prof S Astley
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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(MRC NW-DMS) Lung cell surface glycocalyx regulation of the immune response to the exposome

The University of Manchester
Division of Immunology, Immunity to Infection and Respiratory Medicine
  Research Group: Division of Immunology, Immunity to Infection and Respiratory Medicine
The lung airspace is a key interface between the body and the outside world, optimised to facilitate oxygen transfer into the body whilst limiting damage from external factors. Read more
 Supervisors: Prof D Thornton, Dr DD Dyer, Dr M Menon
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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(MRC NW-DMS) Harnessing Visible-Light Catalysis for RNA Drug Target Discovery

The University of Manchester
Department of Chemistry
There is increasing evidence that small molecules regulate cellular processes by targeting nucleic acids far more extensively than appreciated, opening up largely untapped therapeutic target space. Read more
 Supervisors: Dr A Trowbridge, Dr JD Worboys
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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(MRC NW-DMS) Developing and testing personalised approaches to understand and reduce indoor environmental exposures during pregnancy

The University of Manchester
Division of Developmental Biology and Medicine
  Research Group: Division of Developmental Biology and Medicine
Air pollution is a major environmental threat to health, especially during pregnancy linking to millions of babies globally being born too small or too soon each year. Read more
 Supervisors: Dr L Higgins, Dr T Bannan, Dr MG Gittins, Dr S Omeara
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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(MRC NW-DMS CASE) Transcutaneous auricular vagal nerve stimulation for anxiety in autism spectrum conditions

The University of Manchester
Division of Psychology and Mental Health
Are you interested in translating neuroscience discoveries into treatments that has the potential to change lives? This CASE PhD offers a unique opportunity to investigate a novel brain stimulation intervention for anxiety in autistic young people, combining academic research with a 3-month industrial placement with our partner company. Read more
 Supervisors: Dr S Garg, Dr A Kafkas, Dr C Lea-Carnall
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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(MRC NW-DMS) Exploring the interplay between blood flow, cell shape and division orientation in endothelial cells

The University of Manchester
Division of Cardiovascular Sciences
Proliferation of adult endothelial cells is known to be induced in vascular tissues in numerous disease states, including cardiovascular disease and cancer. Read more
 Supervisors: Dr H Lovegrove, Dr AM Miller, Dr T Finegan, Dr D Bergstralh, Dr S Herbert
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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(MRC NW-DMS CASE) Biomarkers in Human Osteochondral Donor and Recipients; Biomarkers Predictive of Disease Pathway and Clinical Outcome

The University of Manchester
Division of Cell Matrix Biology and Regenerative Medicine
Effective osteoarthritis treatment is one of the biggest unmet needs in society. This PhD directly translates into improvements in patient outcomes, with the aim to halt or delay progress of early osteoarthritis. Read more
 Supervisors: Ms L Biant, Dr G Orozco, Prof S Eyre, Prof MM McNicholas
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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(MRC NW-DMS) Integrating single cell transcriptomics and computational modelling to discover genetic drivers of age-related macular degeneration

The University of Manchester
Division of Evolution, Infection and Genomics
  Research Group: Division of Evolution, Infection and Genomics
Why do some people develop age-related macular degeneration (AMD) while others remain unaffected? Can genetics and artificial intelligence help uncover the earliest biological changes that lead to vision loss?. Read more
 Supervisors: Dr J Ellingford, Prof A Morris, Dr PS Sergouniotis
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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(MRC NW-DMS) Inflammation and immunity in post-stroke neurodegeneration and cognitive decline

The University of Manchester
Division of Cardiovascular Sciences
  Research Group: Division of Cardiovascular Sciences
Stroke is the leading cause of disability worldwide and at least one third of people surviving a stroke develop dementia. There are currently no available treatments to prevent post-stroke dementia. Read more
 Supervisors: Prof C J Smith, Dr J Grainger, Prof S Allan
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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(MRC NW-DMS) Sustainable drug manufacture for next-generation medical imaging

The University of Manchester
Department of Chemistry
  Research Group: Department of Chemistry
Magnetic resonance imaging (MRI) is widely used to diagnose and monitor disease, but often gives limited information about how tissues use nutrients and produce energy. Read more
 Supervisors: Dr J Rowbotham, Dr B Dickie
 27 November 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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