We have 178 MRC PhD Projects, Programmes & Scholarships

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MRC PhD Projects, Programmes & Scholarships

We have 178 MRC PhD Projects, Programmes & Scholarships

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Funded project GW4 BioMed3 MRC DTP - Alternative fates of PINK1 and its role in mitochondrial quality control, energy production and Parkinson’s Disease

BACKGROUND. Mitochondria are organelles of eukaryotic cells critical for energy production (ATP), metabolic regulation and biosynthesis. Read more
 Supervisors: Prof I Collinson, Dr RC Corey
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Funded project GW4 BioMed3 MRC DTP - Overcoming β-lactamase-mediated antibiotic resistance by combining biomolecular simulation and experiment

Rising antibiotic resistance is a major problem for human health. Resistance to β-lactams, the single most important antibiotic class, usually arises through their breakdown by β-lactamases (BLs). Read more
 Supervisors: Dr M van der Kamp, Dr J Spencer, Dr CT Tooke
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Funded project GW4 BioMed3 MRC DTP - Understanding beta-lactam antibiotic targets to improve melioidosis treatment

Melioidosis, caused by the soil-borne Gram-negative bacterium Burkholderia pseudomallei, is an under-recognised tropical disease, with mortality rates that can exceed 40 % for respiratory infections, that causes c. Read more
 Supervisors: Dr J Spencer, Prof A J Mulholland, Dr CT Tooke
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Funded project GW4 BioMed3 MRC DTP - You snooze, you win: harnessing hibernation biology for organ protection

Ever wondered how animals hibernate? How they tolerate near freezing body temperatures and a barely beating heart?Whether one day we might be able to mimic it in critically ill patients?. Read more
 Supervisors: Dr M Ambler, Prof A E Pickering, Dr SM Mastitskaya
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Funded project GW4 BioMed3 MRC DTP - When immune memory becomes corrupted

BACKGROUND. The immune system protects the body from infections and diseases. Some immune cells can remember past threats and respond more effectively if they encounter them again. Read more
 Supervisors: Dr S Koh, Prof C Wuelfing, Prof A Clayton, Dr N Owens
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Funded project GW4 BioMed3 MRC DTP - Cardiac glia: gatekeepers of the stressed heart?

In the brain, astrocytes are active partners of neurons buffering ions, releasing metabolites and signalling molecules (lactate, ATP, glutamate) at "tripartite synapses", and switching to a reactive state under stress that reshapes circuit function. Read more
 Supervisors: Dr V Mosienko, Dr SM Mastitskaya
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Funded project GW4 BioMed3 MRC DTP - How the Golgi Feels Force: Uncovering a Hidden Driver of Osteoarthritis

Osteoarthritis (OA) affects an estimated 10 million people in the UK and is characterised by the progressive breakdown of articular cartilage leading to joint pain, stiffness, and reduced mobility. Read more
 Supervisors: Prof C Hammond, Dr N Stevenson, Dr B Faber, Dr E Blain
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Funded project GW4 BioMed3 MRC DTP - Understanding the link between lipid droplet biology and bone health

Cells require a constant, and tightly regulated supply of nutrients to sustain metabolism and growth. Lipids are particularly important. Read more
 Supervisors: Dr B Carroll, Prof C Hammond, Dr RC Corey, Dr MS Shchepinova
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Investigating Pathogenic Mechanisms And Therapeutic Approaches For mtDNA Mutations In Cellular Models And Patients

Mutations in mitochondrial DNA (mtDNA) are the most common cause of inherited mitochondrial disease and are increasingly implicated in common age-related conditions including neurodegeneration. Read more
 Supervisors: Prof R Horvath, Prof M Minczuk, Dr J van den Ameele
 8 December 2026  PhD Research Project  Funded PhD Project (UK Students Only)
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Investigating Pathogenic Mechanisms And Therapeutic Approaches For mtDNA Mutations In Cellular Models And Patients

Mutations in mitochondrial DNA (mtDNA) are the most common cause of inherited mitochondrial disease and are increasingly implicated in common age-related conditions including neurodegeneration. Read more
 Supervisors: Prof R Horvath, Prof M Minczuk, Dr J van den Ameele
 8 December 2026  PhD Research Project  Funded PhD Project (UK Students Only)
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FULLY FUNDED - Project DC13: AI-driven surveillance for respiratory infections

Background. The threat of a high-impact respiratory pandemic is growing, underscoring the urgent need for advanced surveillance systems. Read more
 Supervisor: Dr A Ho
 8 October 2026  PhD Research Project  Funded PhD Project (Students Worldwide)
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FULLY FUNDED - Project DC12: Virome dynamics in wastewater across urban, rural, and high-risk settings: molecular detection, mutational impact and host risk

To apply, please click institution website. Background. Emerging and re-emerging viruses continue to pose major threats to global health. Read more
 Supervisor: Dr A daSilva Filipe
 8 October 2026  PhD Research Project  Funded PhD Project (Students Worldwide)
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Deciphering the Molecular Mechanisms Underlying the Pathogenicity of mtDNA Mutations

Applications are invited for a fully funded PhD studentship in Professor Hansong Ma's laboratory within the School of Biosciences, University of Birmingham. Read more
 Supervisor: Dr HM Ma
 Year round applications  PhD Research Project  Funded PhD Project (UK Students Only)
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Medication adherence in young people with first episode psychosis: a longitudinal mixed-methods biopsychosocial study of decision making.

Antipsychotic medication can reduce or resolve psychotic symptoms and help prevent relapse, but adherence remains challenging, particularly for young people with first episode psychosis. Read more
 Supervisors: Dr S Roberts, Dr N Bennett, Dr S Sullivan
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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From Multi-OMICs to mechanism: understanding the links between protein turnover and therapy resistance in glioblastoma stem cells

  Research Group: Biomedicine
How do glioblastoma stem cells evade therapy and drive tumour recurrence? This project will address this question by investigating how FGF2-FGFR1 signalling regulates protein homeostasis in these highly aggressive cells. Read more
 Supervisors: Dr F Siebzehnrubl, Dr J Licchesi
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)