We have 178 MRC PhD Projects, Programmes & Scholarships

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MRC PhD Projects, Programmes & Scholarships

We have 178 MRC PhD Projects, Programmes & Scholarships

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Developing Precise Mitochondrial DNA Base Editors For Genome Therapy

Medical Research Council (Cambridge)
Mitochondrial Biology Unit
Background. Mutations in mitochondrial DNA (mtDNA) are the most common cause of inherited mitochondrial disease and are increasingly implicated in common age-related conditions including neurodegeneration. Read more
 Supervisor: Prof M Minczuk
 8 December 2026  PhD Research Project  Funded PhD Project (UK Students Only)
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Developing Precise Mitochondrial DNA Base Editors For Genome Therapy

University of Cambridge
MRC Mitochondrial Biology Unit
Background. Mutations in mitochondrial DNA (mtDNA) are the most common cause of inherited mitochondrial disease and are increasingly implicated in common age-related conditions including neurodegeneration. Read more
 Supervisor: Prof M Minczuk
 8 December 2026  PhD Research Project  Funded PhD Project (UK Students Only)
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Investigating Pathogenic Mechanisms And Therapeutic Targets For mtDNA Mutations

Medical Research Council (Cambridge)
Mitochondrial Biology Unit
Mutations in mitochondrial DNA (mtDNA) are the most common cause of inherited mitochondrial disease and are increasingly implicated in common age-related conditions including neurodegeneration. Read more
 Supervisor: Dr A J Whitworth
 8 December 2026  PhD Research Project  Funded PhD Project (UK Students Only)
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Investigating Pathogenic Mechanisms And Therapeutic Targets For mtDNA Mutations

University of Cambridge
MRC Mitochondrial Biology Unit
Mutations in mitochondrial DNA (mtDNA) are the most common cause of inherited mitochondrial disease and are increasingly implicated in common age-related conditions including neurodegeneration. Read more
 Supervisor: Dr A J Whitworth
 8 December 2026  PhD Research Project  Funded PhD Project (UK Students Only)
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Funded project GW4 BioMed3 MRC DTP - Artificial intelligence to identify fungal susceptibility in the clinical diagnostic laboratory

University of Bristol
MRC GW4 BioMed Doctoral Training Partnership
Fungal infections have become a major and growing global health crisis, causing an estimated 3.8 million deaths each year—surpassing the toll of diseases like tuberculosis and malaria. Read more
 Supervisor: Prof A Dowsey
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Funded project GW4 BioMed3 MRC DTP - Gatekeepers of GPCR Signalling: Degradation Pathways in Health and Diseas

University of Bristol
School of Biochemistry and Biomedical Sciences
G protein-coupled receptors (GPCRs) are the largest family of cellsurface signalling proteins and mediate communication between cells throughout the body and brain. Read more
 Supervisors: Dr A Grieve, Prof I Collinson
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Funded project GW4 BioMed3 MRC DTP - Quantifying the impact of heatwaves on cognition, neuroanatomy, and mitochondrial function

University of Bristol
School of Biological Sciences
Climate change is increasing the frequency, duration, and severity of heatwaves worldwide. In the UK, extreme heat events are becoming increasingly common and are projected to intensify over coming decades. Read more
 Supervisor: Dr H Siviter
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Funded project GW4 BioMed3 MRC DTP - Optimising uptake and personalisation of digital health interventions for under-served groups: a case study with the Drink Less app

University of Bristol
School of Psychology and Neuroscience
Digital health interventions can be effective at changing behaviours and can overcome lots of barriers to receiving face-to-face interventions such as stigma and accessibility. Read more
 Supervisors: Dr C Garnett, Assoc Prof O Maynard, Prof A Attwood
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Funded project GW4 BioMed3 MRC DTP - Quietly healing trauma: enhancing emotional processing during sleep with targeted memory reactivation

University of Bristol
School of Psychology and Neuroscience
Over 80% of people experience a traumatic event during their lifetime; of these, up to ~10% develop post-traumatic stress disorder (PTSD). Read more
 Supervisors: Dr R Purple, Prof M Jones
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Funded project GW4 BioMed3 MRC DTP - Linking neuronal function to mental health: How genetic risk factors impair cognitive flexibility and neural plasticity in schizophrenia.

University of Bristol
School of Psychology and Neuroscience
Genetic risk factors are highly significant in determining susceptibility to a range of psychiatric disorders including anxiety, depression and schizophrenia. Read more
 Supervisor: Prof J Mellor
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Funded project GW4 BioMed3 MRC DTP - Using human genomics, AI and fly disease modelling to study the relationship between sleep and Alzheimer’s disease

University of Bristol
School of Psychology and Neuroscience
Background. Our 24-hour body clock or circadian rhythms controls sleep-wake cycles timing. We helped show rhythms become weaker and sleep fragmented in old age (https://circadiageing.org.uk). Read more
 Supervisor: Prof J Hodge
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Funded project GW4 BioMed3 MRC DTP - Developing brain-activity based non-invasive stimulation techniques for movement disorders

University of Bristol
School of Psychology and Neuroscience
Parkinson’s disease and dystonia are neurological disorders that cause disabling movement impairments. The effectiveness of current treatments varies substantially between individuals, and approximately 20–35% of people with dystonia are dissatisfied with their treatment. Read more
 Supervisors: Dr P Fischer, Prof M Jones
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Funded project GW4 BioMed3 MRC DTP - What drives the pain? Exploring the peripheral component in models of central sensitisation.

University of Bristol
School of Psychology and Neuroscience
Chronic primary pain is pain for more than three months without an identified underlying injury or disease that explains its severity. Read more
 Supervisor: Dr J Dunham
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Funded project GW4 BioMed3 MRC DTP - Molecular basis of CASK mutations and their role in neural development

University of Bristol
School of Psychology and Neuroscience
CASK is a highly conserved, multi-domain scaffolding protein that plays essential roles in synaptic development, neuronal communication, and brain formation. Read more
 Supervisors: Dr RC Corey, Prof J Hodge, Dr A Knapp-Wilson
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Funded project GW4 BioMed3 MRC DTP - Timing is Everything: Aligning Mealtime and Drug Treatment with the Body Clock to Fight Obesity

University of Bristol
School of Psychology and Neuroscience
Life on Earth is subordinate to periodic alterations in the environment, with most notable changes seen from day to night. To adapt to these cyclic changes, living organisms evolved endogenous 24h timekeeping mechanisms named circadian clocks. Read more
 Supervisors: Dr LC Chrobok, Prof HP Piggins
 21 October 2026  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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